U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    IFT70B intraflagellar transport 70B [ Homo sapiens (human) ]

    Gene ID: 150737, updated on 7-Apr-2024

    Summary

    Official Symbol
    IFT70Bprovided by HGNC
    Official Full Name
    intraflagellar transport 70Bprovided by HGNC
    Primary source
    HGNC:HGNC:26425
    See related
    Ensembl:ENSG00000196659 MIM:620742; AllianceGenome:HGNC:26425
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    IFT70; fleer; TTC30B
    Summary
    Predicted to enable intraciliary transport particle B binding activity. Predicted to be involved in intraciliary transport. Predicted to be located in ciliary tip. Predicted to be part of intraciliary transport particle B. Predicted to be active in axonemal microtubule and ciliary basal body. [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See IFT70B in Genome Data Viewer
    Location:
    2q31.2
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (177548998..177552796, complement)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (178031273..178035071, complement)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (178413726..178417524, complement)

    Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene Putative uncharacterized protein FLJ44553 Neighboring gene small nucleolar RNA U13 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12146 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12147 Neighboring gene Sharpr-MPRA regulatory region 2066 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr2:178261250-178261750 Neighboring gene ReSE screen-validated silencer GRCh37_chr2:178275762-178275927 Neighboring gene alkylglycerone phosphate synthase Neighboring gene MPRA-validated peak3947 silencer Neighboring gene uncharacterized LOC105373762 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr2:178338764-178339963 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:178416524-178417328 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr2:178417329-178418132 Neighboring gene uncharacterized LOC124906098 Neighboring gene intraflagellar transport 70A

    Genomic regions, transcripts, and products

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • FLJ30990

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables intraciliary transport particle B binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in cilium assembly NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in intraciliary anterograde transport NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in intraciliary transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in axonemal microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in ciliary tip TAS
    Traceable Author Statement
    more info
     
    located_in cilium NAS
    Non-traceable Author Statement
    more info
    PubMed 
    located_in cilium TAS
    Traceable Author Statement
    more info
     
    part_of intraciliary transport particle B IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of intraciliary transport particle B IPI
    Inferred from Physical Interaction
    more info
    PubMed 

    General protein information

    Preferred Names
    intraflagellar transport protein 70B
    Names
    TPR repeat protein 30B
    tetratricopeptide repeat domain 30B
    tetratricopeptide repeat protein 30B

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_152517.3NP_689730.2  intraflagellar transport protein 70B

      See identical proteins and their annotated locations for NP_689730.2

      Status: VALIDATED

      Source sequence(s)
      AC073834, AI498353, AW007843, BC033795, DA260391, DA557876
      Consensus CDS
      CCDS42784.1
      UniProtKB/Swiss-Prot
      Q63HQ1, Q8N4P2, Q96NE6
      UniProtKB/TrEMBL
      B4DL36
      Related
      ENSP00000386181.2, ENST00000408939.4
      Conserved Domains (2) summary
      TIGR02917
      Location:26217
      PEP_TPR_lipo; putative PEP-CTERM system TPR-repeat lipoprotein
      sd00006
      Location:158182
      TPR; TPR repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

      Range
      177548998..177552796 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060926.1 Alternate T2T-CHM13v2.0

      Range
      178031273..178035071 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)