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    Thumpd3 THUMP domain containing 3 [ Mus musculus (house mouse) ]

    Gene ID: 14911, updated on 23-Jun-2021

    Summary

    Official Symbol
    Thumpd3provided by MGI
    Official Full Name
    THUMP domain containing 3provided by MGI
    Primary source
    MGI:MGI:1277973
    See related
    Ensembl:ENSMUSG00000030264
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gtro; AW556087; Gtrosa26as; Gt(ROSA)26asSor
    Expression
    Ubiquitous expression in testis adult (RPKM 10.3), placenta adult (RPKM 8.3) and 25 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Thumpd3 in Genome Data Viewer
    Location:
    6 E3; 6 52.73 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (113023263..113045239)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (113046302..113068278)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (112996321..113018267)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 23244 Neighboring gene predicted gene, 43868 Neighboring gene gene trap ROSA 26, Philippe Soriano Neighboring gene predicted gene, 22591 Neighboring gene SET domain containing 5 Neighboring gene lipoma HMGIC fusion partner-like protein 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables tRNA (guanine) methyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within methylation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in tRNA methylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    THUMP domain-containing protein 3
    Names
    gene trap ROSA 26 antisense, Philippe Soriano
    gtROSA26asSor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001355266.1NP_001342195.1  THUMP domain-containing protein 3

      Status: VALIDATED

      Source sequence(s)
      AC155722
      Consensus CDS
      CCDS20410.1
      Conserved Domains (2) summary
      cd11715
      Location:42288
      THUMP_AdoMetMT; THUMP domain associated with S-adenosylmethionine-dependent methyltransferases
      pfam01170
      Location:295480
      UPF0020; Putative RNA methylase family UPF0020
    2. NM_008188.3NP_032214.1  THUMP domain-containing protein 3

      See identical proteins and their annotated locations for NP_032214.1

      Status: VALIDATED

      Source sequence(s)
      AC155722
      Consensus CDS
      CCDS20410.1
      UniProtKB/Swiss-Prot
      P97770
      Related
      ENSMUSP00000032398.9, ENSMUST00000032398.15
      Conserved Domains (2) summary
      cd11715
      Location:42288
      THUMP_AdoMetMT; THUMP domain associated with S-adenosylmethionine-dependent methyltransferases
      pfam01170
      Location:295480
      UPF0020; Putative RNA methylase family UPF0020

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      113023263..113045239
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006505579.3XP_006505642.1  THUMP domain-containing protein 3 isoform X1

      See identical proteins and their annotated locations for XP_006505642.1

      UniProtKB/Swiss-Prot
      P97770
      Conserved Domains (2) summary
      cd11715
      Location:42288
      THUMP_AdoMetMT; THUMP domain associated with S-adenosylmethionine-dependent methyltransferases
      pfam01170
      Location:295480
      UPF0020; Putative RNA methylase family UPF0020
    2. XM_006505578.4XP_006505641.1  THUMP domain-containing protein 3 isoform X1

      See identical proteins and their annotated locations for XP_006505641.1

      UniProtKB/Swiss-Prot
      P97770
      Conserved Domains (2) summary
      cd11715
      Location:42288
      THUMP_AdoMetMT; THUMP domain associated with S-adenosylmethionine-dependent methyltransferases
      pfam01170
      Location:295480
      UPF0020; Putative RNA methylase family UPF0020
    3. XM_036165865.1XP_036021758.1  THUMP domain-containing protein 3 isoform X1

      Conserved Domains (2) summary
      cd11715
      Location:42288
      THUMP_AdoMetMT; THUMP domain associated with S-adenosylmethionine-dependent methyltransferases
      pfam01170
      Location:295480
      UPF0020; Putative RNA methylase family UPF0020
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