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    Gsta4 glutathione S-transferase, alpha 4 [ Mus musculus (house mouse) ]

    Gene ID: 14860, updated on 5-Sep-2021

    Summary

    Official Symbol
    Gsta4provided by MGI
    Official Full Name
    glutathione S-transferase, alpha 4provided by MGI
    Primary source
    MGI:MGI:1309515
    See related
    Ensembl:ENSMUSG00000032348
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    mGst; GST5.7; mGsta4
    Expression
    Biased expression in bladder adult (RPKM 693.7), stomach adult (RPKM 118.2) and 1 other tissue See more
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    Genomic context

    See Gsta4 in Genome Data Viewer
    Location:
    9; 9 E1
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (78099248..78116631)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (78191966..78209349)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (78039773..78057156)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA C920006O11 gene Neighboring gene RNA, 7SK, nuclear Neighboring gene preferentially expressed antigen in melanoma like 6 pseudogene Neighboring gene glutathione S-transferase, alpha 1 (Ya)

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables fatty acid binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables glutathione peroxidase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables glutathione transferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables glutathione transferase activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    enables glutathione transferase activity TAS
    Traceable Author Statement
    more info
    PubMed 
    enables organic cyclic compound binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables steroid delta-isomerase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables toxic substance binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in glutathione metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in xenobiotic metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    glutathione S-transferase A4
    Names
    GST A4-4
    GST class-alpha member 4
    GSTA4-4
    glutathione S-transferase 5.7
    NP_034487.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_010357.3NP_034487.2  glutathione S-transferase A4

      See identical proteins and their annotated locations for NP_034487.2

      Status: VALIDATED

      Source sequence(s)
      AI043064, AK008400, AK010098, AK019271, BU953110
      Consensus CDS
      CCDS23357.1
      UniProtKB/Swiss-Prot
      P24472
      Related
      ENSMUSP00000034903.6, ENSMUST00000034903.7
      Conserved Domains (3) summary
      PTZ00057
      Location:1198
      PTZ00057; glutathione s-transferase; Provisional
      cd03208
      Location:86220
      GST_C_Alpha; C-terminal, alpha helical domain of Class Alpha Glutathione S-transferases
      cd03077
      Location:482
      GST_N_Alpha; GST_N family, Class Alpha subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens, ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      78099248..78116631
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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