Format

Send to:

Choose Destination
    • Showing Current items.

    Haspin histone H3 associated protein kinase [ Mus musculus (house mouse) ]

    Gene ID: 14841, updated on 31-Jan-2019

    Summary

    Official Symbol
    Haspinprovided by MGI
    Official Full Name
    histone H3 associated protein kinaseprovided by MGI
    Primary source
    MGI:MGI:1194498
    See related
    Ensembl:ENSMUSG00000050107
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gsg2
    Orthologs

    Genomic context

    See Haspin in Genome Data Viewer
    Location:
    11 B4; 11 45.25 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 11 NC_000077.6 (73135484..73138294, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (72948986..72951796, complement)

    Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4732414G09 gene Neighboring gene calcium/calmodulin-dependent protein kinase kinase 1, alpha Neighboring gene nuclear cap binding subunit 3 Neighboring gene integrin alpha E, epithelial-associated Neighboring gene predicted gene, 35001 Neighboring gene purinergic receptor P2X, ligand-gated ion channel, 5 Neighboring gene ER membrane protein complex subunit 6

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Homology

    Clone Names

    • MGC130563

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    ATP binding ISO
    Inferred from Sequence Orthology
    more info
     
    DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    histone kinase activity (H3-T3 specific) IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    histone kinase activity (H3-T3 specific) ISO
    Inferred from Sequence Orthology
    more info
     
    kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein serine/threonine kinase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    chromatin organization IEA
    Inferred from Electronic Annotation
    more info
     
    histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore ISO
    Inferred from Sequence Orthology
    more info
     
    intracellular signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    intracellular signal transduction IDA
    Inferred from Direct Assay
    more info
    PubMed 
    intracellular signal transduction ISO
    Inferred from Sequence Orthology
    more info
     
    mitotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mitotic sister chromatid cohesion ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of G1/S transition of mitotic cell cycle IDA
    Inferred from Direct Assay
    more info
    PubMed 
    phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    protein localization to chromosome, centromeric region ISO
    Inferred from Sequence Orthology
    more info
     
    protein phosphorylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    spindle ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    serine/threonine-protein kinase haspin
    Names
    germ cell associated 2, haspin
    germ cell-specific gene 2 protein
    haploid germ cell-specific nuclear protein kinase
    NP_034483.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_010353.2NP_034483.1  serine/threonine-protein kinase haspin

      See identical proteins and their annotated locations for NP_034483.1

      Status: VALIDATED

      Source sequence(s)
      AI450094, AV143145, D87326
      Consensus CDS
      CCDS24997.1
      UniProtKB/Swiss-Prot
      Q9Z0R0
      UniProtKB/TrEMBL
      A0A0R4J0P2
      Related
      ENSMUSP00000055806.2, ENSMUST00000052140.2
      Conserved Domains (2) summary
      pfam12330
      Location:666746
      DUF3635; Domain of unknown function (DUF3635)
      cl21453
      Location:439613
      PKc_like; Protein Kinases, catalytic domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000077.6 Reference GRCm38.p4 C57BL/6J

      Range
      73135484..73138294 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCm38.p4 NOD/MrkTac

    Genomic

    1. NT_166317.2 Reference GRCm38.p4 NOD/MrkTac

      Range
      227379..230187 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center