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    Gpr3 G-protein coupled receptor 3 [ Mus musculus (house mouse) ]

    Gene ID: 14748, updated on 5-Jan-2023

    Summary

    Official Symbol
    Gpr3provided by MGI
    Official Full Name
    G-protein coupled receptor 3provided by MGI
    Primary source
    MGI:MGI:101908
    See related
    Ensembl:ENSMUSG00000049649 AllianceGenome:MGI:101908
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gpcr3; Gpcr20; Gpcr21
    Summary
    Predicted to enable G protein-coupled receptor activity. Involved in positive regulation of cold-induced thermogenesis. Acts upstream of or within regulation of meiotic nuclear division. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in cytoplasm and plasma membrane. Is expressed in central nervous system; eye; gonad; and salivary gland. Orthologous to human GPR3 (G protein-coupled receptor 3). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in cortex adult (RPKM 2.5), testis adult (RPKM 2.4) and 10 other tissues See more
    Orthologs
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    Genomic context

    See Gpr3 in Genome Data Viewer
    Location:
    4; 4 D2.3
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (132936651..132939847, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (133209340..133212536, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene nuclear encoded tRNA glycine 1 (anticodon GCC) Neighboring gene WASP family, member 2 Neighboring gene microRNA 7017 Neighboring gene CD164 sialomucin-like 2 Neighboring gene ficolin C pseudogene Neighboring gene mitogen-activated protein kinase kinase kinase 6

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    G-protein coupled receptor 3

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_008154.3NP_032180.1  G-protein coupled receptor 3

      See identical proteins and their annotated locations for NP_032180.1

      Status: VALIDATED

      Source sequence(s)
      AI854631, AK140302, BB851645
      Consensus CDS
      CCDS18743.1
      UniProtKB/Swiss-Prot
      P35413, Q3USD4
      Related
      ENSMUSP00000062083.9, ENSMUST00000052090.9
      Conserved Domains (2) summary
      pfam00001
      Location:57297
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:58162
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      132936651..132939847 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)