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    Got2 glutamatic-oxaloacetic transaminase 2, mitochondrial [ Mus musculus (house mouse) ]

    Gene ID: 14719, updated on 23-Jun-2021

    Summary

    Official Symbol
    Got2provided by MGI
    Official Full Name
    glutamatic-oxaloacetic transaminase 2, mitochondrialprovided by MGI
    Primary source
    MGI:MGI:95792
    See related
    Ensembl:ENSMUSG00000031672
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    mA; FABP; Kyat; Got-2; Kyat4; mAspAT; FABP-pm; AL022787
    Expression
    Ubiquitous expression in heart adult (RPKM 277.4), liver adult (RPKM 151.9) and 26 other tissues See more
    Orthologs
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    Genomic context

    See Got2 in Genome Data Viewer
    Location:
    8 D1; 8 47.79 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (96590761..96615029, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (95864133..95888401, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (98388037..98412265, complement)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 31805 Neighboring gene solute carrier family 38, member 7 Neighboring gene predicted gene, 51586 Neighboring gene predicted gene 8637

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC102129, MGC115763

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables L-aspartate:2-oxoglutarate aminotransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables L-aspartate:2-oxoglutarate aminotransferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables L-aspartate:2-oxoglutarate aminotransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables amino acid binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables carboxylic acid binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables enzyme binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables kynurenine-oxoglutarate transaminase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables phospholipid binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables pyridoxal phosphate binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables transaminase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in T-tubule ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cell surface ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrial inner membrane HDA PubMed 
    located_in mitochondrial inner membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    located_in myelin sheath HDA PubMed 
    located_in perikaryon ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in sarcolemma ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    aspartate aminotransferase, mitochondrial
    Names
    FABP-1
    FABPpm
    fatty acid-binding protein
    glutamate oxaloacetate transaminase 2, mitochondrial
    kynurenine aminotransferase 4
    kynurenine aminotransferase IV
    kynurenine--oxoglutarate transaminase 4
    kynurenine--oxoglutarate transaminase IV
    mitochondrial aspartate aminotransferase
    plasma membrane fatty acid binding protein
    plasma membrane-associated fatty acid-binding protein
    transaminase A
    NP_034455.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_010325.3NP_034455.1  aspartate aminotransferase, mitochondrial

      See identical proteins and their annotated locations for NP_034455.1

      Status: VALIDATED

      Source sequence(s)
      AC127300
      Consensus CDS
      CCDS22568.1
      UniProtKB/Swiss-Prot
      P05202
      Related
      ENSMUSP00000034097.8, ENSMUST00000034097.8
      Conserved Domains (2) summary
      PLN02397
      Location:32430
      PLN02397; aspartate transaminase
      pfam00155
      Location:57425
      Aminotran_1_2; Aminotransferase class I and II

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      96590761..96615029 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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