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    Gdap2 ganglioside-induced differentiation-associated-protein 2 [ Mus musculus (house mouse) ]

    Gene ID: 14547, updated on 31-Jan-2019

    Summary

    Official Symbol
    Gdap2provided by MGI
    Official Full Name
    ganglioside-induced differentiation-associated-protein 2provided by MGI
    Primary source
    MGI:MGI:1338001
    See related
    Ensembl:ENSMUSG00000027865
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C77050; D3Ertd801e
    Expression
    Ubiquitous expression in placenta adult (RPKM 7.1), testis adult (RPKM 6.6) and 28 other tissues See more
    Orthologs

    Genomic context

    See Gdap2 in Genome Data Viewer
    Location:
    3; 3 F2.2
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 3 NC_000069.6 (100162463..100206989)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (99966441..100010904)

    Chromosome 3 - NC_000069.6Genomic Context describing neighboring genes Neighboring gene sperm associated antigen 17 Neighboring gene ribosomal protein L36, pseudogene 7 Neighboring gene WD repeat domain 3 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene predicted gene, 32471

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    response to retinoic acid IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    ganglioside-induced differentiation-associated protein 2

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_010269.3NP_034399.1  ganglioside-induced differentiation-associated protein 2

      See identical proteins and their annotated locations for NP_034399.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript.
      Source sequence(s)
      AK004887, AL606742, BY084929
      Consensus CDS
      CCDS17675.1
      UniProtKB/Swiss-Prot
      Q9DBL2
      Related
      ENSMUSP00000029459.3, ENSMUST00000029459.9
      Conserved Domains (3) summary
      COG2110
      Location:56222
      YmdB; O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain [Translation, ribosomal structure and biogenesis]
      cd02905
      Location:54193
      Macro_GDAP2_like; Macro domain, GDAP2_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose ...
      pfam13716
      Location:350471
      CRAL_TRIO_2; Divergent CRAL/TRIO domain

    RNA

    1. NR_104341.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate splice site in an internal exon compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AK004887, AK161122, AL606742, BY084929

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000069.6 Reference GRCm38.p4 C57BL/6J

      Range
      100162463..100206989
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006501001.2XP_006501064.1  ganglioside-induced differentiation-associated protein 2 isoform X1

      See identical proteins and their annotated locations for XP_006501064.1

      UniProtKB/Swiss-Prot
      Q9DBL2
      Conserved Domains (3) summary
      COG2110
      Location:56222
      YmdB; O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain [Translation, ribosomal structure and biogenesis]
      cd02905
      Location:54193
      Macro_GDAP2_like; Macro domain, GDAP2_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose ...
      pfam13716
      Location:350471
      CRAL_TRIO_2; Divergent CRAL/TRIO domain

    RNA

    1. XR_001783651.1 RNA Sequence

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