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    Ftl1 ferritin light polypeptide 1 [ Mus musculus (house mouse) ]

    Gene ID: 14325, updated on 23-Jun-2021

    Summary

    Official Symbol
    Ftl1provided by MGI
    Official Full Name
    ferritin light polypeptide 1provided by MGI
    Primary source
    MGI:MGI:95589
    See related
    Ensembl:ENSMUSG00000050708
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ft; Ftl; L-fe; Ftl-1; L-ferritin
    Expression
    Ubiquitous expression in liver adult (RPKM 4436.7), adrenal adult (RPKM 2649.8) and 23 other tissues See more
    Orthologs
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    Genomic context

    See Ftl1 in Genome Data Viewer
    Location:
    7; 7 B3
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (45107368..45109310, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (45457944..45459886, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (52713314..52715256, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene luteinizing hormone beta Neighboring gene RuvB-like protein 2 Neighboring gene glycogen synthase 1, muscle Neighboring gene BCL2-associated X protein Neighboring gene dihydrodiol dehydrogenase (dimeric) Neighboring gene tubby-like protein 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2)  1 citation
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC102130, MGC102131, MGC118079, MGC118080

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ferric iron binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables ferrous iron binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables iron ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in intracellular sequestering of iron ion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in autolysosome ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in endocytic vesicle lumen TAS
    Traceable Author Statement
    more info
     
    located_in extracellular region TAS
    Traceable Author Statement
    more info
     
    part_of intracellular ferritin complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    ferritin light chain 1
    Names
    ferritin L subunit 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_010240.2NP_034370.2  ferritin light chain 1

      See identical proteins and their annotated locations for NP_034370.2

      Status: VALIDATED

      Source sequence(s)
      AK169159, BC081462, BY134899
      Consensus CDS
      CCDS39952.1
      UniProtKB/TrEMBL
      Q9CPX4
      Related
      ENSMUSP00000092002.5, ENSMUST00000094434.13
      Conserved Domains (1) summary
      cd00904
      Location:10177
      Ferritin; Ferritin iron storage proteins

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      45107368..45109310 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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