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    Ppm1g protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform [ Mus musculus (house mouse) ]

    Gene ID: 14208, updated on 5-Aug-2018

    Summary

    Official Symbol
    Ppm1gprovided by MGI
    Official Full Name
    protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoformprovided by MGI
    Primary source
    MGI:MGI:106065
    See related
    Ensembl:ENSMUSG00000029147 Vega:OTTMUSG00000055347
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Fin13; AI385652
    Expression
    Ubiquitous expression in testis adult (RPKM 177.4), liver E14 (RPKM 82.5) and 28 other tissues See more
    Orthologs

    Genomic context

    See Ppm1g in Genome Data Viewer
    Location:
    5 B1; 5 17.27 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 5 NC_000071.6 (31202668..31220545, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (31505041..31522918, complement)

    Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene sorting nexin 17 Neighboring gene zinc finger protein 513 Neighboring gene predicted gene, 46908 Neighboring gene predicted gene 9970 Neighboring gene nuclear receptor binding protein 1 Neighboring gene predicted gene, 46909 Neighboring gene keratinocyte associated protein 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Pathways from BioSystems

    • mRNA processing, organism-specific biosystem (from WikiPathways)
      mRNA processing, organism-specific biosystemAdapted from Reactome, see: [http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_1675.1 REACT 1675.1] This process describes the conversion of precursor messenger RNA into mature messenge...

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    catalytic activity IEA
    Inferred from Electronic Annotation
    more info
     
    cation binding IEA
    Inferred from Electronic Annotation
    more info
     
    hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    phosphoprotein phosphatase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein serine/threonine phosphatase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    cell cycle arrest IDA
    Inferred from Direct Assay
    more info
    PubMed 
    peptidyl-threonine dephosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    protein dephosphorylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    protein phosphatase 1G
    Names
    PP2C-gamma
    fibroblast growth factor inducible 13
    fibroblast growth factor-inducible protein 13
    protein phosphatase 1C
    protein phosphatase 2C isoform gamma
    protein phosphatase magnesium-dependent 1 gamma
    NP_032040.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_008014.3NP_032040.1  protein phosphatase 1G

      See identical proteins and their annotated locations for NP_032040.1

      Status: PROVISIONAL

      Source sequence(s)
      AC114619
      Consensus CDS
      CCDS19179.1
      UniProtKB/Swiss-Prot
      Q61074
      Related
      ENSMUSP00000031032.7, OTTMUSP00000072215, ENSMUST00000031032.10, OTTMUST00000137018
      Conserved Domains (2) summary
      smart00332
      Location:25110
      PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain
      cd00143
      Location:321502
      PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000071.6 Reference GRCm38.p4 C57BL/6J

      Range
      31202668..31220545 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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