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    Ppm1g protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform [ Mus musculus (house mouse) ]

    Gene ID: 14208, updated on 23-Jun-2021

    Summary

    Official Symbol
    Ppm1gprovided by MGI
    Official Full Name
    protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoformprovided by MGI
    Primary source
    MGI:MGI:106065
    See related
    Ensembl:ENSMUSG00000029147
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Fin; Fin13; AI385652
    Expression
    Ubiquitous expression in testis adult (RPKM 177.4), liver E14 (RPKM 82.5) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Ppm1g in Genome Data Viewer
    Location:
    5 B1; 5 17.27 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (31360012..31377889, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (31202668..31220545, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (31505041..31522918, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene sorting nexin 17 Neighboring gene zinc finger protein 513 Neighboring gene nuclear receptor binding protein 1 Neighboring gene keratinocyte associated protein 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables cation binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables phosphoprotein phosphatase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein serine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine/threonine phosphatase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein threonine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in peptidyl-threonine dephosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein dephosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within protein dephosphorylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within regulation of cell cycle IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    protein phosphatase 1G
    Names
    PP2C-gamma
    fibroblast growth factor inducible 13
    fibroblast growth factor-inducible protein 13
    protein phosphatase 1C
    protein phosphatase magnesium-dependent 1 gamma
    NP_032040.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_008014.3NP_032040.1  protein phosphatase 1G

      See identical proteins and their annotated locations for NP_032040.1

      Status: PROVISIONAL

      Source sequence(s)
      AC114619
      Consensus CDS
      CCDS19179.1
      UniProtKB/Swiss-Prot
      Q61074
      Related
      ENSMUSP00000031032.8, ENSMUST00000031032.11
      Conserved Domains (2) summary
      smart00332
      Location:25110
      PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain
      cd00143
      Location:321502
      PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      31360012..31377889 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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