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    Fem1b feminization 1 homolog b (C. elegans) [ Mus musculus (house mouse) ]

    Gene ID: 14155, updated on 31-Jan-2019

    Summary

    Official Symbol
    Fem1bprovided by MGI
    Official Full Name
    feminization 1 homolog b (C. elegans)provided by MGI
    Primary source
    MGI:MGI:1335087
    See related
    Ensembl:ENSMUSG00000032244
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    mKIAA0396
    Expression
    Broad expression in testis adult (RPKM 35.7), placenta adult (RPKM 32.6) and 24 other tissues See more
    Orthologs

    Genomic context

    See Fem1b in Genome Data Viewer
    Location:
    9 B; 9 33.87 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 9 NC_000075.6 (62791824..62811648, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (62639631..62659455, complement)

    Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene integrin alpha 11 Neighboring gene dCTP pyrophosphatase 1 pseudogene Neighboring gene ribsomal protein S2 pseudogene Neighboring gene ceroid-lipofuscinosis, neuronal 6 Neighboring gene calmodulin-like 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    death receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    ubiquitin-protein transferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    protein fem-1 homolog B
    Names
    F1A-alpha
    FEM1-beta
    fem-1-like death receptor-binding protein alpha
    fem-1-like in apoptotic pathway protein alpha
    mt-Fem

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_010193.4NP_034323.1  protein fem-1 homolog B

      See identical proteins and their annotated locations for NP_034323.1

      Status: VALIDATED

      Source sequence(s)
      AI854655, AK122272, AK149329, AK160393, CJ047815
      Consensus CDS
      CCDS23266.1
      UniProtKB/Swiss-Prot
      Q9Z2G0
      Related
      ENSMUSP00000034775.8, ENSMUST00000034775.9
      Conserved Domains (4) summary
      cd00204
      Location:87207
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      sd00045
      Location:87118
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:11117
      Ank_2; Ankyrin repeats (3 copies)
      cl26073
      Location:101366
      Ank_2; Ankyrin repeats (3 copies)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000075.6 Reference GRCm38.p4 C57BL/6J

      Range
      62791824..62811648 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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