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    SCP2D1 SCP2 sterol binding domain containing 1 [ Homo sapiens (human) ]

    Gene ID: 140856, updated on 5-Mar-2024

    Summary

    Official Symbol
    SCP2D1provided by HGNC
    Official Full Name
    SCP2 sterol binding domain containing 1provided by HGNC
    Primary source
    HGNC:HGNC:16211
    See related
    Ensembl:ENSG00000132631 AllianceGenome:HGNC:16211
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    HSD22; C20orf79; dJ1068E13.2
    Summary
    Predicted to enable sterol binding activity. Predicted to be involved in phospholipid transport; positive regulation of intracellular cholesterol transport; and steroid biosynthetic process. [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    NEW
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    Genomic context

    Location:
    20p11.23
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 20 NC_000020.11 (18813783..18814378)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 20 NC_060944.1 (18865625..18866220)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (18794427..18795022)

    Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:18774369-18774908 Neighboring gene eukaryotic translation elongation factor 1 alpha 1 pseudogene 34 Neighboring gene long intergenic non-protein coding RNA 652 Neighboring gene SCP2D1 antisense RNA 1 Neighboring gene lysosome cell death regulator Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr20:18897388-18898587 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17594 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17595 Neighboring gene uncharacterized LOC102724734 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr20:19028509-19029708 Neighboring gene uncharacterized LOC107985442 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr20:19077722-19078921 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12704 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr20:19188093-19188651 Neighboring gene uncharacterized LOC101929547

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    SCP2 sterol-binding domain-containing protein 1
    Names
    sterol carrier protein 2-like protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_178483.3NP_848578.1  SCP2 sterol-binding domain-containing protein 1

      See identical proteins and their annotated locations for NP_848578.1

      Status: VALIDATED

      Source sequence(s)
      AF418570
      Consensus CDS
      CCDS13139.1
      UniProtKB/Swiss-Prot
      Q548A4, Q9UJQ7
      UniProtKB/TrEMBL
      Q6X959
      Related
      ENSP00000366645.2, ENST00000377428.4
      Conserved Domains (1) summary
      pfam02036
      Location:60151
      SCP2; SCP-2 sterol transfer family

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000020.11 Reference GRCh38.p14 Primary Assembly

      Range
      18813783..18814378
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060944.1 Alternate T2T-CHM13v2.0

      Range
      18865625..18866220
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)