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    Ankrd6 ankyrin repeat domain 6 [ Mus musculus (house mouse) ]

    Gene ID: 140577, updated on 23-Jun-2021

    Summary

    Official Symbol
    Ankrd6provided by MGI
    Official Full Name
    ankyrin repeat domain 6provided by MGI
    Primary source
    MGI:MGI:2154278
    See related
    Ensembl:ENSMUSG00000040183
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    di
    Summary
    This gene encodes a protein which is thought to be involved in the Wnt signaling pathway and embryonic axis formation. Similar genes have been found in human, rhesus macaque, and zebrafish. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
    Expression
    Biased expression in frontal lobe adult (RPKM 5.9), CNS E14 (RPKM 4.0) and 12 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Ankrd6 in Genome Data Viewer
    Location:
    4; 4 A5
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (32804027..32950884, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (32804027..32950885, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (32891010..33037801, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene midasin AAA ATPase 1 Neighboring gene LYR motif containing 2 Neighboring gene enoyl-CoA hydratase domain-containing protein 2, mitochondrial pseudogene Neighboring gene ribosomal protein, large, P1 pseudogene Neighboring gene Ras-related GTP binding D

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    ankyrin repeat domain-containing protein 6
    Names
    diversin

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001012450.1NP_001012453.1  ankyrin repeat domain-containing protein 6

      See identical proteins and their annotated locations for NP_001012453.1

      Status: REVIEWED

      Description
      Transcript Variant: This transcript represents variant 1. Variants 1-4 all encode the same protein.
      Source sequence(s)
      AV290829, BC065177, CF531081
      Consensus CDS
      CCDS18018.1
      UniProtKB/Swiss-Prot
      Q69ZU8
      Related
      ENSMUSP00000041300.5, ENSMUST00000035719.11
      Conserved Domains (3) summary
      PHA03095
      Location:29265
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:4172
      ANK; ANK repeat [structural motif]
      pfam11179
      Location:520643
      DUF2967; Protein of unknown function (DUF2967)
    2. NM_001012451.1NP_001012454.1  ankyrin repeat domain-containing protein 6

      See identical proteins and their annotated locations for NP_001012454.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1-4 all encode the same protein.
      Source sequence(s)
      AV290829, BC065177, CF533090
      Consensus CDS
      CCDS18018.1
      UniProtKB/Swiss-Prot
      Q69ZU8
      Related
      ENSMUSP00000081802.2, ENSMUST00000084750.8
      Conserved Domains (3) summary
      PHA03095
      Location:29265
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:4172
      ANK; ANK repeat [structural motif]
      pfam11179
      Location:520643
      DUF2967; Protein of unknown function (DUF2967)
    3. NM_001355587.1NP_001342516.1  ankyrin repeat domain-containing protein 6

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1-4 all encode the same protein.
      Source sequence(s)
      AV290829, BC065177, CJ057243
      Consensus CDS
      CCDS18018.1
      Conserved Domains (3) summary
      PHA03095
      Location:29265
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:4172
      ANK; ANK repeat [structural motif]
      pfam11179
      Location:520643
      DUF2967; Protein of unknown function (DUF2967)
    4. NM_080471.3NP_536719.2  ankyrin repeat domain-containing protein 6

      See identical proteins and their annotated locations for NP_536719.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1-4 all encode the same protein.
      Source sequence(s)
      AV290829, BC065177, CF531081
      Consensus CDS
      CCDS18018.1
      UniProtKB/Swiss-Prot
      Q69ZU8
      Related
      ENSMUSP00000081801.2, ENSMUST00000084749.8
      Conserved Domains (3) summary
      PHA03095
      Location:29265
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:4172
      ANK; ANK repeat [structural motif]
      pfam11179
      Location:520643
      DUF2967; Protein of unknown function (DUF2967)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      32804027..32950884 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036163674.1XP_036019567.1  ankyrin repeat domain-containing protein 6 isoform X4

      Conserved Domains (2) summary
      PHA03095
      Location:19232
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:107138
      ANK; ANK repeat [structural motif]
    2. XM_036163672.1XP_036019565.1  ankyrin repeat domain-containing protein 6 isoform X2

      Conserved Domains (2) summary
      PHA03095
      Location:19232
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:107138
      ANK; ANK repeat [structural motif]
    3. XM_036163673.1XP_036019566.1  ankyrin repeat domain-containing protein 6 isoform X3

      Conserved Domains (2) summary
      PHA03095
      Location:29265
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:4172
      ANK; ANK repeat [structural motif]
    4. XM_036163675.1XP_036019568.1  ankyrin repeat domain-containing protein 6 isoform X5

      Conserved Domains (2) summary
      sd00045
      Location:1848
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:22114
      Ank_2; Ankyrin repeats (3 copies)
    5. XM_011249919.4XP_011248221.1  ankyrin repeat domain-containing protein 6 isoform X1

      See identical proteins and their annotated locations for XP_011248221.1

      UniProtKB/Swiss-Prot
      Q69ZU8
      Conserved Domains (3) summary
      PHA03095
      Location:29265
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:4172
      ANK; ANK repeat [structural motif]
      pfam11179
      Location:520643
      DUF2967; Protein of unknown function (DUF2967)
    6. XM_011249921.4XP_011248223.1  ankyrin repeat domain-containing protein 6 isoform X1

      See identical proteins and their annotated locations for XP_011248223.1

      UniProtKB/Swiss-Prot
      Q69ZU8
      Conserved Domains (3) summary
      PHA03095
      Location:29265
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:4172
      ANK; ANK repeat [structural motif]
      pfam11179
      Location:520643
      DUF2967; Protein of unknown function (DUF2967)
    7. XM_011249920.4XP_011248222.1  ankyrin repeat domain-containing protein 6 isoform X1

      See identical proteins and their annotated locations for XP_011248222.1

      UniProtKB/Swiss-Prot
      Q69ZU8
      Conserved Domains (3) summary
      PHA03095
      Location:29265
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:4172
      ANK; ANK repeat [structural motif]
      pfam11179
      Location:520643
      DUF2967; Protein of unknown function (DUF2967)
    8. XM_011249924.4XP_011248226.1  ankyrin repeat domain-containing protein 6 isoform X1

      See identical proteins and their annotated locations for XP_011248226.1

      UniProtKB/Swiss-Prot
      Q69ZU8
      Conserved Domains (3) summary
      PHA03095
      Location:29265
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:4172
      ANK; ANK repeat [structural motif]
      pfam11179
      Location:520643
      DUF2967; Protein of unknown function (DUF2967)
    9. XM_011249922.4XP_011248224.1  ankyrin repeat domain-containing protein 6 isoform X1

      See identical proteins and their annotated locations for XP_011248224.1

      UniProtKB/Swiss-Prot
      Q69ZU8
      Conserved Domains (3) summary
      PHA03095
      Location:29265
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:4172
      ANK; ANK repeat [structural motif]
      pfam11179
      Location:520643
      DUF2967; Protein of unknown function (DUF2967)
    10. XM_011249923.4XP_011248225.1  ankyrin repeat domain-containing protein 6 isoform X1

      See identical proteins and their annotated locations for XP_011248225.1

      UniProtKB/Swiss-Prot
      Q69ZU8
      Conserved Domains (3) summary
      PHA03095
      Location:29265
      PHA03095; ankyrin-like protein; Provisional
      sd00045
      Location:4172
      ANK; ANK repeat [structural motif]
      pfam11179
      Location:520643
      DUF2967; Protein of unknown function (DUF2967)
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