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    ACTRT1 actin related protein T1 [ Homo sapiens (human) ]

    Gene ID: 139741, updated on 27-Nov-2024

    Summary

    Official Symbol
    ACTRT1provided by HGNC
    Official Full Name
    actin related protein T1provided by HGNC
    Primary source
    HGNC:HGNC:24027
    See related
    Ensembl:ENSG00000123165 MIM:300487; AllianceGenome:HGNC:24027
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    AIP1; ARIP1; ARPT1; HSD27
    Summary
    This gene encodes a protein related to the cytoskeletal protein beta-actin. This protein is a major component of the calyx in the perinuclear theca of mammalian sperm heads, and it therefore likely functions in spermatid formation. This gene is intronless and is similar to a related gene located on chromosome 1. A related pseudogene has also been identified approximately 75 kb downstream of this gene on chromosome X. [provided by RefSeq, May 2010]
    Orthologs
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    Genomic context

    See ACTRT1 in Genome Data Viewer
    Location:
    Xq25
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (128050962..128052403, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (126364457..126365898, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (127184941..127186382, complement)

    Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene kinesin family member 2A pseudogene Neighboring gene NANOG hESC enhancer GRCh37_chrX:126884520-126885021 Neighboring gene uncharacterized LOC105373333 Neighboring gene zinc finger protein 674 pseudogene Neighboring gene BTG anti-proliferation factor 3 pseudogene 1

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Clone Names

    • KIAA0705, MGC26590

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables chromatin binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in actin cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_021358.1 RefSeqGene

      Range
      5001..6442
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_138289.4NP_612146.1  actin-related protein T1

      See identical proteins and their annotated locations for NP_612146.1

      Status: REVIEWED

      Source sequence(s)
      BC014597, DB452140, DB510229
      Consensus CDS
      CCDS14611.1
      UniProtKB/Swiss-Prot
      Q6X7C1, Q8TDG2, Q96L10
      Related
      ENSP00000360165.3, ENST00000371124.5
      Conserved Domains (1) summary
      smart00268
      Location:9376
      ACTIN; Actin

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

      Range
      128050962..128052403 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060947.1 Alternate T2T-CHM13v2.0

      Range
      126364457..126365898 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)