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    Elf1 E74 like ETS transcription factor 1 [ Mus musculus (house mouse) ]

    Gene ID: 13709, updated on 23-Jun-2021

    Summary

    Official Symbol
    Elf1provided by MGI
    Official Full Name
    E74 like ETS transcription factor 1provided by MGI
    Primary source
    MGI:MGI:107180
    See related
    Ensembl:ENSMUSG00000036461
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    p70; Elf-; Sts1; Elf-1; mElf-1
    Expression
    Ubiquitous expression in thymus adult (RPKM 22.3), bladder adult (RPKM 13.4) and 26 other tissues See more
    Orthologs
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    Genomic context

    See Elf1 in Genome Data Viewer
    Location:
    14; 14 D3
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (79718632..79819931)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (79481174..79582491)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (79881001..79982283)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene mitochondrial translational release factor 1 Neighboring gene kelch repeat and BTB (POZ) domain containing 7 Neighboring gene kelch repeat and BTB (POZ) domain containing 6 Neighboring gene WW domain binding protein 4 Neighboring gene nuclear encoded tRNA glutamic acid 4 (anticodon TTC) Neighboring gene claspin homolog pseudogene Neighboring gene SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) Neighboring gene chondromodulin

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1)  1 citation
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    ETS-related transcription factor Elf-1
    Names
    E74-like factor 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001286411.1NP_001273340.1  ETS-related transcription factor Elf-1 isoform 1

      See identical proteins and their annotated locations for NP_001273340.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein (isoform 1).
      Source sequence(s)
      AK132456, AK142807
      Consensus CDS
      CCDS27301.1
      UniProtKB/Swiss-Prot
      Q60775
      UniProtKB/TrEMBL
      Q3UQ47, Q3V1H4
      Related
      ENSMUSP00000106459.2, ENSMUST00000110835.3
      Conserved Domains (2) summary
      smart00413
      Location:207289
      ETS; erythroblast transformation specific domain
      pfam12310
      Location:2111
      Elf-1_N; Transcription factor protein N terminal
    2. NM_001286412.1NP_001273341.1  ETS-related transcription factor Elf-1 isoform 2

      See identical proteins and their annotated locations for NP_001273341.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR and lacks an alternate, in-frame exon in the coding region compared to variant 1. The resulting protein (isoform 2) is shorter but has the same N- and C-termini compared to isoform 1.
      Source sequence(s)
      AK132456, AK142807
      Consensus CDS
      CCDS88722.1
      UniProtKB/TrEMBL
      Q3UQ47, Q3V1H4
      Related
      ENSMUSP00000153956.2, ENSMUST00000227192.2
      Conserved Domains (2) summary
      smart00413
      Location:170252
      ETS; erythroblast transformation specific domain
      pfam12310
      Location:269
      Elf-1_N; Transcription factor protein N terminal
    3. NM_007920.4NP_031946.1  ETS-related transcription factor Elf-1 isoform 1

      See identical proteins and their annotated locations for NP_031946.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longer protein (isoform 1). Variants 1 and 2 encode the same protein.
      Source sequence(s)
      AK132456, AK142807, BC057134
      Consensus CDS
      CCDS27301.1
      UniProtKB/Swiss-Prot
      Q60775
      UniProtKB/TrEMBL
      Q3UQ47, Q3V1H4
      Related
      ENSMUSP00000046515.6, ENSMUST00000040131.13
      Conserved Domains (2) summary
      smart00413
      Location:207289
      ETS; erythroblast transformation specific domain
      pfam12310
      Location:2111
      Elf-1_N; Transcription factor protein N terminal

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      79718632..79819931
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011244948.4XP_011243250.1  ETS-related transcription factor Elf-1 isoform X1

      See identical proteins and their annotated locations for XP_011243250.1

      Conserved Domains (2) summary
      smart00413
      Location:170252
      ETS; erythroblast transformation specific domain
      pfam12310
      Location:269
      Elf-1_N; Transcription factor protein N terminal
    2. XM_030247642.2XP_030103502.1  ETS-related transcription factor Elf-1 isoform X2

      Conserved Domains (3) summary
      PLN02226
      Location:92192
      PLN02226; 2-oxoglutarate dehydrogenase E2 component
      smart00413
      Location:207289
      ETS; erythroblast transformation specific domain
      pfam12310
      Location:2111
      Elf-1_N; Transcription factor protein N terminal
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