U.S. flag

An official website of the United States government


Send to:

Choose Destination
    • Showing Current items.

    Ddx19a DEAD box helicase 19a [ Mus musculus (house mouse) ]

    Gene ID: 13680, updated on 23-Nov-2023


    Official Symbol
    Ddx19aprovided by MGI
    Official Full Name
    DEAD box helicase 19aprovided by MGI
    Primary source
    See related
    Ensembl:ENSMUSG00000015023 AllianceGenome:MGI:99526
    Gene type
    protein coding
    RefSeq status
    Mus musculus
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    DBP5; Ddx19; Eif4a-rs1
    Predicted to enable RNA binding activity and RNA helicase activity. Predicted to be involved in poly(A)+ mRNA export from nucleus. Predicted to be located in cytoplasm. Predicted to be active in cytoplasmic stress granule and nucleus. Is expressed in several structures, including central nervous system and sensory organ. Orthologous to human DDX19A (DEAD-box helicase 19A). [provided by Alliance of Genome Resources, Apr 2022]
    Ubiquitous expression in CNS E11.5 (RPKM 23.6), liver E14 (RPKM 17.2) and 28 other tissues See more
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Ddx19a in Genome Data Viewer
    8 E1; 8 57.86 cM
    Exon count:
    Annotation release Status Assembly Chr Location
    RS_2023_04 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (111701623..111724456, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (110974991..110997823, complement)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene ST3 beta-galactoside alpha-2,3-sialyltransferase 2 Neighboring gene predicted gene, 46052 Neighboring gene predicted gene, 39251 Neighboring gene predicted gene, 51551 Neighboring gene DEAD box helicase 19b Neighboring gene microRNA 3473d Neighboring gene alanyl-tRNA synthetase 1 Neighboring gene exosome component 6

    Genomic regions, transcripts, and products


    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a


    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?



    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Endonuclease-mediated (1)  1 citation

    Pathways from PubChem


    Products Interactant Other Gene Complex Source Pubs Description

    General gene information


    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    enables RNA helicase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    enables helicase activity IEA
    Inferred from Electronic Annotation
    more info
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    Process Evidence Code Pubs
    involved_in poly(A)+ mRNA export from nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    is_active_in cytoplasmic stress granule IBA
    Inferred from Biological aspect of Ancestor
    more info
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info

    General protein information

    Preferred Names
    ATP-dependent RNA helicase DDX19A
    DEAD (Asp-Glu-Ala-Asp) box polypeptide 19a
    DEAD box RNA helicase DEAD5
    DEAD box protein 19A
    DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 19
    Ddx19-like protein
    eukaryotic translation initiation factor 4A-related sequence 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001417182.1NP_001404111.1  ATP-dependent RNA helicase DDX19A isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC093451, AC132945
    2. NM_007916.2NP_031942.2  ATP-dependent RNA helicase DDX19A isoform 1

      See identical proteins and their annotated locations for NP_031942.2

      Status: VALIDATED

      Source sequence(s)
      AK146548, BG094410, BY302446
      Consensus CDS
      Q543M2, Q61655, Q921R0
      ENSMUSP00000047898.8, ENSMUST00000040416.8
      Conserved Domains (3) summary
      PTZ00424; helicase 45; Provisional
      HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2023_04

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J


    1. NC_000074.7 Reference GRCm39 C57BL/6J

      111701623..111724456 complement
      GenBank, FASTA, Sequence Viewer (Graphics)