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    Ddx19a DEAD box helicase 19a [ Mus musculus (house mouse) ]

    Gene ID: 13680, updated on 23-Jun-2021

    Summary

    Official Symbol
    Ddx19aprovided by MGI
    Official Full Name
    DEAD box helicase 19aprovided by MGI
    Primary source
    MGI:MGI:99526
    See related
    Ensembl:ENSMUSG00000015023
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    DBP; DBP5; Ddx19; Eif4a; Eif4a-rs1
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 23.6), liver E14 (RPKM 17.2) and 28 other tissues See more
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    Genomic context

    See Ddx19a in Genome Data Viewer
    Location:
    8; 8 E1
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (111701183..111724474, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (110974991..110997823, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (113498891..113521723, complement)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene ST3 beta-galactoside alpha-2,3-sialyltransferase 2 Neighboring gene predicted gene, 46052 Neighboring gene predicted gene, 39251 Neighboring gene predicted gene, 51551 Neighboring gene DEAD box helicase 19b Neighboring gene microRNA 3473d Neighboring gene alanyl-tRNA synthetase Neighboring gene exosome component 6

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Endonuclease-mediated (1)  1 citation

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    • Homologs of the Ddx19a gene: The Ddx19a gene is conserved in human, chimpanzee, dog, cow, rat, zebrafish, C.elegans, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, and A.thaliana.
    • Orthologs

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables RNA helicase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables helicase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in poly(A)+ mRNA export from nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytoplasmic stress granule IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    ATP-dependent RNA helicase DDX19A
    Names
    DEAD (Asp-Glu-Ala-Asp) box polypeptide 19a
    DEAD box RNA helicase DEAD5
    DEAD box protein 19A
    DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 19
    Ddx19-like protein
    eukaryotic translation initiation factor 4A-related sequence 1
    mDEAD5
    NP_031942.2
    XP_036009643.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_007916.2NP_031942.2  ATP-dependent RNA helicase DDX19A

      See identical proteins and their annotated locations for NP_031942.2

      Status: VALIDATED

      Source sequence(s)
      AK146548, BG094410, BY302446
      Consensus CDS
      CCDS22668.1
      UniProtKB/Swiss-Prot
      Q61655
      Related
      ENSMUSP00000047898.8, ENSMUST00000040416.8
      Conserved Domains (3) summary
      PTZ00424
      Location:90468
      PTZ00424; helicase 45; Provisional
      cd00079
      Location:306441
      HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
      cl21455
      Location:93295
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      111701183..111724474 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036153750.1XP_036009643.1  ATP-dependent RNA helicase DDX19A isoform X1

      Conserved Domains (2) summary
      cd18787
      Location:216352
      SF2_C_DEAD; C-terminal helicase domain of the DEAD box helicases
      cl28899
      Location:9212
      DEAD-like_helicase_N; N-terminal helicase domain of the DEAD-box helicase superfamily
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