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    E2f5 E2F transcription factor 5 [ Mus musculus (house mouse) ]

    Gene ID: 13559, updated on 23-Jun-2021

    Summary

    Official Symbol
    E2f5provided by MGI
    Official Full Name
    E2F transcription factor 5provided by MGI
    Primary source
    MGI:MGI:105091
    See related
    Ensembl:ENSMUSG00000027552
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    E2F-5; AU024671
    Expression
    Ubiquitous expression in ovary adult (RPKM 13.0), CNS E11.5 (RPKM 11.8) and 28 other tissues See more
    Orthologs
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    Genomic context

    See E2f5 in Genome Data Viewer
    Location:
    3; 3 A1
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (14638370..14671369)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (14578602..14606309)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (14578671..14606309)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene leucine rich repeat and coiled-coil domain containing 1 Neighboring gene ribosomal biogenesis factor Neighboring gene predicted gene, 54191 Neighboring gene carbonic anhydrase 13

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA-binding transcription activator activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables DNA-binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables transcription factor binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of RNA polymerase II transcription regulator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in fibrillar center ISO
    Inferred from Sequence Orthology
    more info
     
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear envelope TAS
    Traceable Author Statement
    more info
    PubMed 
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in sarcoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    part_of transcription regulator complex IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_007892.2NP_031918.2  transcription factor E2F5

      See identical proteins and their annotated locations for NP_031918.2

      Status: PROVISIONAL

      Source sequence(s)
      BC003220
      Consensus CDS
      CCDS38391.1
      UniProtKB/Swiss-Prot
      Q61502
      Related
      ENSMUSP00000029069.7, ENSMUST00000029069.13
      Conserved Domains (3) summary
      cd14660
      Location:118222
      E2F_DD; Dimerization domain of E2F transcription factors
      pfam02319
      Location:42106
      E2F_TDP; E2F/DP family winged-helix DNA-binding domain
      pfam12764
      Location:760
      Gly-rich_Ago1; Glycine-rich region of argonaut

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      14638370..14671369
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006530051.4XP_006530114.1  transcription factor E2F5 isoform X1

      Conserved Domains (1) summary
      cd14660
      Location:171
      E2F_DD; Dimerization domain of E2F transcription factors
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