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    Drg2 developmentally regulated GTP binding protein 2 [ Mus musculus (house mouse) ]

    Gene ID: 13495, updated on 3-Feb-2019

    Summary

    Official Symbol
    Drg2provided by MGI
    Official Full Name
    developmentally regulated GTP binding protein 2provided by MGI
    Primary source
    MGI:MGI:1342307
    See related
    Ensembl:ENSMUSG00000020537
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    DRG-2; AI255295; AI461605
    Expression
    Ubiquitous expression in limb E14.5 (RPKM 26.9), ovary adult (RPKM 25.2) and 28 other tissues See more
    Orthologs

    Genomic context

    See Drg2 in Genome Data Viewer
    Location:
    11 B2; 11 37.81 cM
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 11 NC_000077.6 (60454617..60468752)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (60268119..60282207)

    Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene predicted gene 12268 Neighboring gene ribosomal protein S4, X-linked pseudogene Neighboring gene myosin XV Neighboring gene alkB homolog 5, RNA demethylase

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    GTP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    GTPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    RNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    cytoplasmic translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrion HDA PubMed 
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    developmentally-regulated GTP-binding protein 2
    Names
    TRAFAC GTPase DRG2
    translation factor GTPase DRG2

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_021354.2NP_067329.1  developmentally-regulated GTP-binding protein 2

      See identical proteins and their annotated locations for NP_067329.1

      Status: VALIDATED

      Source sequence(s)
      AL596090
      Consensus CDS
      CCDS24791.1
      UniProtKB/Swiss-Prot
      Q9QXB9
      Related
      ENSMUSP00000018568.3, ENSMUST00000018568.3
      Conserved Domains (1) summary
      COG1163
      Location:1364
      Rbg1; Ribosome-interacting GTPase 1 [Translation, ribosomal structure and biogenesis]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000077.6 Reference GRCm38.p4 C57BL/6J

      Range
      60454617..60468752
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006532153.3XP_006532216.1  developmentally-regulated GTP-binding protein 2 isoform X1

      Conserved Domains (3) summary
      cd01666
      Location:208282
      TGS_DRG_C; TGS_DRG_C: DRG (developmentally regulated GTP-binding protein) represents a family of GTP-binding proteins that includes two members, DRG1 and DRG2. DRG1 and DRG2 have a C-terminal TGS domain (named after the ThrRS, GTPase, and SpoT proteins where it ...
      cd01896
      Location:1214
      DRG; Developmentally Regulated GTP-binding protein (DRG)
      PRK09602
      Location:7281
      PRK09602; translation-associated GTPase; Reviewed
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