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    Drg1 developmentally regulated GTP binding protein 1 [ Mus musculus (house mouse) ]

    Gene ID: 13494, updated on 23-Jun-2021

    Summary

    Official Symbol
    Drg1provided by MGI
    Official Full Name
    developmentally regulated GTP binding protein 1provided by MGI
    Primary source
    MGI:MGI:1343297
    See related
    Ensembl:ENSMUSG00000020457
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Nedd; DRG-1; Nedd3; NEDD-3; AA408859; AI132520
    Expression
    Ubiquitous expression in placenta adult (RPKM 29.0), CNS E11.5 (RPKM 28.8) and 27 other tissues See more
    Orthologs
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    Genomic context

    See Drg1 in Genome Data Viewer
    Location:
    11; 11 A1
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (3199907..3221882, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (3249907..3266464, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (3149925..3166389, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene Sfi1 homolog, spindle assembly associated (yeast) Neighboring gene Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived), pseudogene 2 Neighboring gene eukaryotic translation initiation factor 4E nuclear import factor 1 Neighboring gene predicted gene, 51877 Neighboring gene POZ (BTB) and AT hook containing zinc finger 1 Neighboring gene predicted gene 12592 Neighboring gene predicted gene 11944 Neighboring gene phosphoinositide-3-kinase interacting protein 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables GTP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables GTPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables microtubule binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables potassium ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in positive regulation of microtubule polymerization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of mitotic spindle assembly ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    part_of polysome ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    developmentally-regulated GTP-binding protein 1
    Names
    GTP-binding protein
    TRAFAC GTPase DRG1
    neural precursor cell expressed developmentally down-regulated protein 3
    translation factor GTPase DRG1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_007879.2NP_031905.1  developmentally-regulated GTP-binding protein 1

      See identical proteins and their annotated locations for NP_031905.1

      Status: VALIDATED

      Source sequence(s)
      AL671968
      Consensus CDS
      CCDS24355.1
      UniProtKB/Swiss-Prot
      P32233
      UniProtKB/TrEMBL
      Q5NBZ3
      Related
      ENSMUSP00000020741.6, ENSMUST00000020741.12
      Conserved Domains (1) summary
      COG1163
      Location:1367
      Rbg1; Ribosome-interacting GTPase 1 [Translation, ribosomal structure and biogenesis]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      3199907..3221882 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017314249.3XP_017169738.1  developmentally-regulated GTP-binding protein 1 isoform X1

      Conserved Domains (1) summary
      COG1163
      Location:1334
      Rbg1; Ribosome-interacting GTPase 1 [Translation, ribosomal structure and biogenesis]
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