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    Dnm2 dynamin 2 [ Mus musculus (house mouse) ]

    Gene ID: 13430, updated on 18-Sep-2018

    Summary

    Official Symbol
    Dnm2provided by MGI
    Official Full Name
    dynamin 2provided by MGI
    Primary source
    MGI:MGI:109547
    See related
    Ensembl:ENSMUSG00000033335 Vega:OTTMUSG00000038087
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Dyn2; Udnm; b2b2159Clo
    Expression
    Ubiquitous expression in duodenum adult (RPKM 68.5), colon adult (RPKM 65.8) and 28 other tissues See more
    Orthologs

    Genomic context

    See Dnm2 in Genome Data Viewer
    Location:
    9 A3; 9 7.79 cM
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 9 NC_000075.6 (21424908..21507759)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (21229389..21311568)

    Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 36198 Neighboring gene interleukin enhancer binding factor 3 Neighboring gene predicted gene, 16853 Neighboring gene queuine tRNA-ribosyltransferase catalytic subunit 1 Neighboring gene predicted gene, 46104 Neighboring gene microRNA 199a-1 Neighboring gene transmembrane p24 trafficking protein 1 Neighboring gene cDNA sequence AB124611 Neighboring gene coactivator-associated arginine methyltransferase 1 Neighboring gene Yip1 domain family, member 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (2) 
    • Targeted (5)  1 citation
    • Chemically induced (ENU) (1) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    D2 dopamine receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    GTP binding IEA
    Inferred from Electronic Annotation
    more info
     
    GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    GTPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    SH3 domain binding ISO
    Inferred from Sequence Orthology
    more info
     
    WW domain binding ISO
    Inferred from Sequence Orthology
    more info
     
    hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nitric-oxide synthase binding ISO
    Inferred from Sequence Orthology
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    phosphatidylinositol 3-kinase regulatory subunit binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein-containing complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    G protein-coupled receptor internalization ISO
    Inferred from Sequence Orthology
    more info
     
    Golgi to plasma membrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    aorta development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cellular response to dopamine ISO
    Inferred from Sequence Orthology
    more info
     
    coronary vasculature development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    endocytosis IEA
    Inferred from Electronic Annotation
    more info
     
    macropinocytosis ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of membrane tubulation ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of non-motile cilium assembly ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of transforming growth factor beta receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    neuron projection morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    phagocytosis IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of clathrin-dependent endocytosis ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of endocytosis ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of lamellipodium assembly ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of nitric oxide biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of phagocytosis ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of sodium:potassium-exchanging ATPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of substrate adhesion-dependent cell spreading ISO
    Inferred from Sequence Orthology
    more info
     
    postsynaptic neurotransmitter receptor internalization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    receptor internalization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    receptor internalization ISO
    Inferred from Sequence Orthology
    more info
     
    receptor-mediated endocytosis ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of Golgi organization ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of Rac protein signal transduction ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of axon extension ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of synapse structure or activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    synaptic vesicle budding from presynaptic endocytic zone membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    synaptic vesicle endocytosis IDA
    Inferred from Direct Assay
    more info
    PubMed 
    synaptic vesicle endocytosis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    transferrin transport ISO
    Inferred from Sequence Orthology
    more info
     
    ventricular septum development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    Golgi membrane ISO
    Inferred from Sequence Orthology
    more info
     
    axon IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cell junction ISO
    Inferred from Sequence Orthology
    more info
     
    cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    clathrin-coated endocytic vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    clathrin-coated pit ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasmic vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    dendritic spine IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    dendritic spine head IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    endosome ISO
    Inferred from Sequence Orthology
    more info
     
    glutamatergic synapse ISO
    Inferred from Sequence Orthology
    more info
     
    colocalizes_with growth cone ISO
    Inferred from Sequence Orthology
    more info
     
    lamellipodium ISO
    Inferred from Sequence Orthology
    more info
     
    membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    microtubule ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    perinuclear region of cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    phagocytic cup ISO
    Inferred from Sequence Orthology
    more info
     
    photoreceptor inner segment IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    postsynaptic density IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    postsynaptic density, intracellular component ISO
    Inferred from Sequence Orthology
    more info
     
    postsynaptic endocytic zone membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    postsynaptic membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    postsynaptic membrane ISO
    Inferred from Sequence Orthology
    more info
     
    protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     
    ruffle membrane ISO
    Inferred from Sequence Orthology
    more info
     
    synapse IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    trans-Golgi network ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    dynamin-2
    NP_001034609.1
    NP_001240822.1
    NP_001240823.1
    NP_031897.2
    XP_006510036.1
    XP_006510037.1
    XP_006510038.1
    XP_006510039.1
    XP_006510040.1
    XP_006510041.1
    XP_006510042.1
    XP_006510043.1
    XP_006510044.1
    XP_006510045.1
    XP_006510046.1
    XP_006510047.1
    XP_006510048.1
    XP_017168614.1
    XP_017168615.1
    XP_017168616.1
    XP_017168617.1
    XP_017168618.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001039520.2NP_001034609.1  dynamin-2 isoform 2

      See identical proteins and their annotated locations for NP_001034609.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate splice site in the 3' coding region compared to variant 1. The resulting protein (isoform 2) is shorter but has the same N- and C-termini compared to isoform 1.
      Source sequence(s)
      AA221527, AK157844, AK171566, BY275016
      Consensus CDS
      CCDS57660.1
      UniProtKB/TrEMBL
      Q3TCR7
      Related
      ENSMUSP00000134243.1, OTTMUSP00000055074, ENSMUST00000173397.7, OTTMUST00000098110
      Conserved Domains (5) summary
      smart00053
      Location:6245
      DYNc; Dynamin, GTPase
      cd01256
      Location:520629
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:216501
      Dynamin_M; Dynamin central region
      pfam02212
      Location:651739
      GED; Dynamin GTPase effector domain
      cl26386
      Location:745865
      DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
    2. NM_001253893.1NP_001240822.1  dynamin-2 isoform 1

      See identical proteins and their annotated locations for NP_001240822.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest variant and it encodes the longest protein (isoform 1).
      Source sequence(s)
      AA221527, AK005012, AK150046, AK157844, BY275016, BY549643
      Consensus CDS
      CCDS57657.1
      UniProtKB/Swiss-Prot
      P39054
      Related
      ENSMUSP00000133564.1, OTTMUSP00000055080, ENSMUST00000172482.7, OTTMUST00000098121
      Conserved Domains (5) summary
      smart00053
      Location:6245
      DYNc; Dynamin, GTPase
      cd01256
      Location:520629
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:216501
      Dynamin_M; Dynamin central region
      pfam02212
      Location:651739
      GED; Dynamin GTPase effector domain
      cl26464
      Location:737868
      Atrophin-1; Atrophin-1 family
    3. NM_001253894.1NP_001240823.1  dynamin-2 isoform 4

      See identical proteins and their annotated locations for NP_001240823.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) contains an alternate 3' terminal exon compared to variant 1. The resulting protein (isoform 4) has a shorter and distinct C-terminus compared to isoform 1.
      Source sequence(s)
      AK005012, BQ031151, BY275016, CD540553
      Consensus CDS
      CCDS57658.1
      UniProtKB/Swiss-Prot
      P39054
      UniProtKB/TrEMBL
      Q3T9X3
      Related
      ENSMUSP00000128961.2, OTTMUSP00000055073, ENSMUST00000165766.8, OTTMUST00000098109
      Conserved Domains (5) summary
      smart00053
      Location:6245
      DYNc; Dynamin, GTPase
      cd01256
      Location:520629
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:216501
      Dynamin_M; Dynamin central region
      pfam02212
      Location:651739
      GED; Dynamin GTPase effector domain
      cl26464
      Location:737836
      Atrophin-1; Atrophin-1 family
    4. NM_001357718.1NP_001344647.1  dynamin-2 isoform 5

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) lacks an alternate exon and contains another alternate exon compared to variant 1. The resulting isoform (5) has the same N- and C-termini and the same length but differs in an internal segment compared to isoform 1.
      Source sequence(s)
      AC163748
      Conserved Domains (5) summary
      smart00053
      Location:6245
      DYNc; Dynamin, GTPase
      cd01256
      Location:520629
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:216501
      Dynamin_M; Dynamin central region
      pfam02212
      Location:651739
      GED; Dynamin GTPase effector domain
      cl26464
      Location:737868
      Atrophin-1; Atrophin-1 family
    5. NM_001357719.1NP_001344648.1  dynamin-2 isoform 6

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) lacks an alternate in-frame exon and differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (6) lacks an alternate internal segment and has a shorter and distinct C-terminus compared to isoform 1.
      Source sequence(s)
      AC163748
      Conserved Domains (5) summary
      smart00053
      Location:6245
      DYNc; Dynamin, GTPase
      cd01256
      Location:514625
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:216501
      Dynamin_M; Dynamin central region
      pfam02212
      Location:647735
      GED; Dynamin GTPase effector domain
      cl26464
      Location:733832
      Atrophin-1; Atrophin-1 family
    6. NM_001357721.1NP_001344650.1  dynamin-2 isoform 7

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7) lacks two alternate exons, contains another alternate exon, and differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (7) lacks an alternate internal segment, differs in another internal segment, and has a shorter and distinct C-terminus compared to isoform 1.
      Source sequence(s)
      AC163748
      Conserved Domains (5) summary
      smart00053
      Location:6245
      DYNc; Dynamin, GTPase
      cd01256
      Location:514625
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:216501
      Dynamin_M; Dynamin central region
      pfam02212
      Location:647735
      GED; Dynamin GTPase effector domain
      cl26464
      Location:733832
      Atrophin-1; Atrophin-1 family
    7. NM_007871.2NP_031897.2  dynamin-2 isoform 3

      See identical proteins and their annotated locations for NP_031897.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks an alternate exon in the coding region compared to variant 1. The resulting protein (isoform 3) is shorter but has the same N- and C-termini compared to isoform 1.
      Source sequence(s)
      AA221527, AK005012, AK157844, BY275016, BY549643
      Consensus CDS
      CCDS57659.1
      UniProtKB/Swiss-Prot
      P39054
      Related
      ENSMUSP00000088616.6, OTTMUSP00000055076, ENSMUST00000091087.12, OTTMUST00000098112
      Conserved Domains (5) summary
      smart00053
      Location:6245
      DYNc; Dynamin, GTPase
      cd01256
      Location:514625
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:216501
      Dynamin_M; Dynamin central region
      pfam02212
      Location:647735
      GED; Dynamin GTPase effector domain
      cl26464
      Location:733864
      Atrophin-1; Atrophin-1 family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000075.6 Reference GRCm38.p4 C57BL/6J

      Range
      21424908..21507759
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006509984.3XP_006510047.1  dynamin-2 isoform X17

      Conserved Domains (3) summary
      smart00053
      Location:6245
      DYNc; Dynamin, GTPase
      COG0699
      Location:78498
      CrfC; Replication fork clamp-binding protein CrfC (dynamin-like GTPase family) [Replication, recombination and repair]
      pfam01031
      Location:217498
      Dynamin_M; Dynamin central region
    2. XM_006509978.2XP_006510041.1  dynamin-2 isoform X7

      Conserved Domains (7) summary
      smart00053
      Location:6245
      DYNc; Dynamin, GTPase
      COG0699
      Location:78498
      CrfC; Replication fork clamp-binding protein CrfC (dynamin-like GTPase family) [Replication, recombination and repair]
      cd01256
      Location:530639
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam00169
      Location:530633
      PH; PH domain
      pfam01031
      Location:217498
      Dynamin_M; Dynamin central region
      pfam02212
      Location:661749
      GED; Dynamin GTPase effector domain
      pfam16666
      Location:768830
      MAGI_u5; Unstructured region on MAGI
    3. XM_017313126.1XP_017168615.1  dynamin-2 isoform X10

    4. XM_006509982.2XP_006510045.1  dynamin-2 isoform X14

      Related
      ENSMUSP00000134696.1, OTTMUSP00000055077, ENSMUST00000174050.7, OTTMUST00000098113
      Conserved Domains (5) summary
      smart00053
      Location:6245
      DYNc; Dynamin, GTPase
      cd01256
      Location:514625
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:216501
      Dynamin_M; Dynamin central region
      pfam02212
      Location:647735
      GED; Dynamin GTPase effector domain
      cl26464
      Location:733832
      Atrophin-1; Atrophin-1 family
    5. XM_006509981.2XP_006510044.1  dynamin-2 isoform X13

      Conserved Domains (5) summary
      smart00053
      Location:6245
      DYNc; Dynamin, GTPase
      cd01256
      Location:520629
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:216501
      Dynamin_M; Dynamin central region
      pfam02212
      Location:651739
      GED; Dynamin GTPase effector domain
      cl26464
      Location:737836
      Atrophin-1; Atrophin-1 family
    6. XM_017313129.1XP_017168618.1  dynamin-2 isoform X15

      Conserved Domains (5) summary
      smart00053
      Location:6245
      DYNc; Dynamin, GTPase
      cd01256
      Location:514625
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:216501
      Dynamin_M; Dynamin central region
      pfam02212
      Location:647735
      GED; Dynamin GTPase effector domain
      cl26464
      Location:733832
      Atrophin-1; Atrophin-1 family
    7. XM_006509976.2XP_006510039.1  dynamin-2 isoform X4

      Conserved Domains (7) summary
      smart00053
      Location:6245
      DYNc; Dynamin, GTPase
      COG0699
      Location:78498
      CrfC; Replication fork clamp-binding protein CrfC (dynamin-like GTPase family) [Replication, recombination and repair]
      cd01256
      Location:524635
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam00169
      Location:526629
      PH; PH domain
      pfam01031
      Location:217498
      Dynamin_M; Dynamin central region
      pfam02212
      Location:657745
      GED; Dynamin GTPase effector domain
      pfam16666
      Location:764826
      MAGI_u5; Unstructured region on MAGI
    8. XM_017313125.1XP_017168614.1  dynamin-2 isoform X5

    9. XM_017313127.1XP_017168616.1  dynamin-2 isoform X11

    10. XM_006509980.2XP_006510043.1  dynamin-2 isoform X9

      Conserved Domains (5) summary
      smart00053
      Location:6245
      DYNc; Dynamin, GTPase
      cd01256
      Location:514625
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:216501
      Dynamin_M; Dynamin central region
      pfam02212
      Location:647735
      GED; Dynamin GTPase effector domain
      cl26464
      Location:733864
      Atrophin-1; Atrophin-1 family
    11. XM_017313128.1XP_017168617.1  dynamin-2 isoform X12

      Conserved Domains (5) summary
      smart00053
      Location:6245
      DYNc; Dynamin, GTPase
      cd01256
      Location:514625
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:216501
      Dynamin_M; Dynamin central region
      pfam02212
      Location:647735
      GED; Dynamin GTPase effector domain
      cl26386
      Location:741861
      DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
    12. XM_006509973.1XP_006510036.1  dynamin-2 isoform X1

      Conserved Domains (7) summary
      smart00053
      Location:6245
      DYNc; Dynamin, GTPase
      COG0699
      Location:78498
      CrfC; Replication fork clamp-binding protein CrfC (dynamin-like GTPase family) [Replication, recombination and repair]
      cd01256
      Location:530639
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam00169
      Location:530633
      PH; PH domain
      pfam01031
      Location:217498
      Dynamin_M; Dynamin central region
      pfam02212
      Location:661749
      GED; Dynamin GTPase effector domain
      pfam16666
      Location:768830
      MAGI_u5; Unstructured region on MAGI
    13. XM_006509975.1XP_006510038.1  dynamin-2 isoform X3

      Conserved Domains (7) summary
      smart00053
      Location:6245
      DYNc; Dynamin, GTPase
      COG0699
      Location:78498
      CrfC; Replication fork clamp-binding protein CrfC (dynamin-like GTPase family) [Replication, recombination and repair]
      cd01256
      Location:530639
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam00169
      Location:530633
      PH; PH domain
      pfam01031
      Location:217498
      Dynamin_M; Dynamin central region
      pfam02212
      Location:661749
      GED; Dynamin GTPase effector domain
      pfam16666
      Location:768830
      MAGI_u5; Unstructured region on MAGI
    14. XM_006509979.1XP_006510042.1  dynamin-2 isoform X8

      Conserved Domains (5) summary
      smart00053
      Location:6245
      DYNc; Dynamin, GTPase
      cd01256
      Location:520629
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:216501
      Dynamin_M; Dynamin central region
      pfam02212
      Location:651739
      GED; Dynamin GTPase effector domain
      cl26386
      Location:745865
      DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
    15. XM_006509974.1XP_006510037.1  dynamin-2 isoform X2

      Conserved Domains (7) summary
      smart00053
      Location:6245
      DYNc; Dynamin, GTPase
      COG0699
      Location:78498
      CrfC; Replication fork clamp-binding protein CrfC (dynamin-like GTPase family) [Replication, recombination and repair]
      cd01256
      Location:530639
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam00169
      Location:530633
      PH; PH domain
      pfam01031
      Location:217498
      Dynamin_M; Dynamin central region
      pfam02212
      Location:661749
      GED; Dynamin GTPase effector domain
      pfam16666
      Location:768830
      MAGI_u5; Unstructured region on MAGI
    16. XM_006509977.1XP_006510040.1  dynamin-2 isoform X6

      UniProtKB/TrEMBL
      G3X9G4
      Related
      ENSMUSP00000072199.7, OTTMUSP00000055075, ENSMUST00000072362.13, OTTMUST00000098111
      Conserved Domains (5) summary
      smart00053
      Location:6245
      DYNc; Dynamin, GTPase
      cd01256
      Location:520629
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:216501
      Dynamin_M; Dynamin central region
      pfam02212
      Location:651739
      GED; Dynamin GTPase effector domain
      cl26464
      Location:737868
      Atrophin-1; Atrophin-1 family
    17. XM_006509983.1XP_006510046.1  dynamin-2 isoform X16

      Conserved Domains (7) summary
      COG0699
      Location:1340
      CrfC; Replication fork clamp-binding protein CrfC (dynamin-like GTPase family) [Replication, recombination and repair]
      cd01256
      Location:372481
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam00169
      Location:372475
      PH; PH domain
      pfam01031
      Location:59340
      Dynamin_M; Dynamin central region
      pfam02212
      Location:503591
      GED; Dynamin GTPase effector domain
      pfam16666
      Location:610672
      MAGI_u5; Unstructured region on MAGI
      cl21455
      Location:187
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    18. XM_006509985.3XP_006510048.1  dynamin-2 isoform X18

      Conserved Domains (5) summary
      cd01256
      Location:124233
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam00169
      Location:124227
      PH; PH domain
      pfam01031
      Location:192
      Dynamin_M; Dynamin central region
      pfam02212
      Location:255343
      GED; Dynamin GTPase effector domain
      pfam16666
      Location:362424
      MAGI_u5; Unstructured region on MAGI

    RNA

    1. XR_001778793.1 RNA Sequence

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