Format

Send to:

Choose Destination
    • Showing Current items.

    Dnm2 dynamin 2 [ Mus musculus (house mouse) ]

    Gene ID: 13430, updated on 5-Sep-2021

    Summary

    Official Symbol
    Dnm2provided by MGI
    Official Full Name
    dynamin 2provided by MGI
    Primary source
    MGI:MGI:109547
    See related
    Ensembl:ENSMUSG00000033335
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Dyn; Dyn2; Udnm; b2b2159C; b2b2159Clo
    Expression
    Ubiquitous expression in duodenum adult (RPKM 68.5), colon adult (RPKM 65.8) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Dnm2 in Genome Data Viewer
    Location:
    9 A3; 9 7.79 cM
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (21336167..21419055)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (21424908..21507759)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (21229389..21311568)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene interleukin enhancer binding factor 3 Neighboring gene predicted gene, 16853 Neighboring gene queuine tRNA-ribosyltransferase catalytic subunit 1 Neighboring gene predicted gene, 46104 Neighboring gene uncharacterized LOC118567667 Neighboring gene microRNA 199a-1 Neighboring gene transmembrane p24 trafficking protein 1 Neighboring gene cDNA sequence AB124611 Neighboring gene coactivator-associated arginine methyltransferase 1 Neighboring gene predicted gene, 39303

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (2) 
    • Targeted (8)  1 citation
    • Chemically induced (ENU) (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables D2 dopamine receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables GTPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables SH3 domain binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables WW domain binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables nitric-oxide synthase binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables phosphatidylinositol 3-kinase regulatory subunit binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein-containing complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor internalization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in Golgi to plasma membrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within aorta development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in cellular response to dopamine ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within coronary vasculature development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in endocytosis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in macropinocytosis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of membrane tubulation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of non-motile cilium assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of transforming growth factor beta receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in neuron projection morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within phagocytosis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of P-type sodium:potassium-exchanging transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of clathrin-dependent endocytosis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of endocytosis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of lamellipodium assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of nitric oxide biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of phagocytosis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of substrate adhesion-dependent cell spreading ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in receptor internalization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in receptor internalization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in receptor-mediated endocytosis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of Golgi organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of Rac protein signal transduction ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of axon extension ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in synaptic vesicle endocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in synaptic vesicle endocytosis IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in synaptic vesicle endocytosis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in transferrin transport ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within ventricular septum development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in Golgi membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cell junction ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in clathrin-coated endocytic vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in clathrin-coated pit IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in clathrin-coated pit ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endosome ISO
    Inferred from Sequence Orthology
    more info
     
    colocalizes_with growth cone ISO
    Inferred from Sequence Orthology
    more info
     
    located_in lamellipodium ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    is_active_in microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in microtubule ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in perinuclear region of cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in phagocytic cup ISO
    Inferred from Sequence Orthology
    more info
     
    located_in photoreceptor inner segment IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in postsynaptic membrane ISO
    Inferred from Sequence Orthology
    more info
     
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in ruffle membrane ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in synapse IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in trans-Golgi network ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    dynamin-2
    NP_001034609.1
    NP_001240822.1
    NP_001240823.1
    NP_001344647.1
    NP_001344648.1
    NP_001344650.1
    NP_031897.2
    XP_006510036.1
    XP_006510037.1
    XP_006510039.1
    XP_006510042.1
    XP_006510043.1
    XP_006510044.1
    XP_017168616.1
    XP_017168617.1
    XP_030099903.1
    XP_030099904.1
    XP_030099905.1
    XP_030099906.1
    XP_036010492.1
    XP_036010493.1
    XP_036010494.1
    XP_036010495.1
    XP_036010496.1
    XP_036010497.1
    XP_036010498.1
    XP_036010499.1
    XP_036010500.1
    XP_036010501.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001039520.2NP_001034609.1  dynamin-2 isoform 2

      See identical proteins and their annotated locations for NP_001034609.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate splice site in the 3' coding region compared to variant 1. The resulting protein (isoform 2) is shorter but has the same N- and C-termini compared to isoform 1.
      Source sequence(s)
      AA221527, AK157844, AK171566, BY275016
      Consensus CDS
      CCDS57660.1
      UniProtKB/TrEMBL
      Q3TCR7
      Related
      ENSMUSP00000134243.2, ENSMUST00000173397.8
      Conserved Domains (5) summary
      smart00053
      Location:6245
      DYNc; Dynamin, GTPase
      PRK14951
      Location:745865
      PRK14951; DNA polymerase III subunits gamma and tau; Provisional
      cd01256
      Location:520629
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:216502
      Dynamin_M; Dynamin central region
      pfam02212
      Location:650739
      GED; Dynamin GTPase effector domain
    2. NM_001253893.1NP_001240822.1  dynamin-2 isoform 1

      See identical proteins and their annotated locations for NP_001240822.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest variant and it encodes the longest protein (isoform 1).
      Source sequence(s)
      AA221527, AK005012, AK150046, AK157844, BY275016, BY549643
      Consensus CDS
      CCDS57657.1
      UniProtKB/Swiss-Prot
      P39054
      Related
      ENSMUSP00000133564.2, ENSMUST00000172482.8
      Conserved Domains (5) summary
      smart00053
      Location:6245
      DYNc; Dynamin, GTPase
      PHA03247
      Location:737868
      PHA03247; large tegument protein UL36; Provisional
      cd01256
      Location:520629
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:216502
      Dynamin_M; Dynamin central region
      pfam02212
      Location:650739
      GED; Dynamin GTPase effector domain
    3. NM_001253894.1NP_001240823.1  dynamin-2 isoform 4

      See identical proteins and their annotated locations for NP_001240823.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) contains an alternate 3' terminal exon compared to variant 1. The resulting protein (isoform 4) has a shorter and distinct C-terminus compared to isoform 1.
      Source sequence(s)
      AK005012, BQ031151, BY275016, CD540553
      Consensus CDS
      CCDS57658.1
      UniProtKB/Swiss-Prot
      P39054
      UniProtKB/TrEMBL
      Q3T9X3
      Related
      ENSMUSP00000128961.3, ENSMUST00000165766.9
      Conserved Domains (5) summary
      smart00053
      Location:6245
      DYNc; Dynamin, GTPase
      PHA03247
      Location:737836
      PHA03247; large tegument protein UL36; Provisional
      cd01256
      Location:520629
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:216502
      Dynamin_M; Dynamin central region
      pfam02212
      Location:650739
      GED; Dynamin GTPase effector domain
    4. NM_001357718.1NP_001344647.1  dynamin-2 isoform 5

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) lacks an alternate exon and contains another alternate exon compared to variant 1. The resulting isoform (5) has the same N- and C-termini and the same length but differs in an internal segment compared to isoform 1.
      Source sequence(s)
      AC163748
      Consensus CDS
      CCDS90515.1
      Related
      ENSMUSP00000072199.8, ENSMUST00000072362.14
      Conserved Domains (5) summary
      smart00053
      Location:6245
      DYNc; Dynamin, GTPase
      PHA03247
      Location:737868
      PHA03247; large tegument protein UL36; Provisional
      cd01256
      Location:520629
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:216502
      Dynamin_M; Dynamin central region
      pfam02212
      Location:650739
      GED; Dynamin GTPase effector domain
    5. NM_001357719.1NP_001344648.1  dynamin-2 isoform 6

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) lacks an alternate in-frame exon and differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (6) lacks an alternate internal segment and has a shorter and distinct C-terminus compared to isoform 1.
      Source sequence(s)
      AC163748
      Related
      ENSMUSP00000134696.2, ENSMUST00000174050.8
      Conserved Domains (5) summary
      smart00053
      Location:6245
      DYNc; Dynamin, GTPase
      PHA03247
      Location:733832
      PHA03247; large tegument protein UL36; Provisional
      cd01256
      Location:514625
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:216502
      Dynamin_M; Dynamin central region
      pfam02212
      Location:646735
      GED; Dynamin GTPase effector domain
    6. NM_001357721.1NP_001344650.1  dynamin-2 isoform 7

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7) lacks two alternate exons, contains another alternate exon, and differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (7) lacks an alternate internal segment, differs in another internal segment, and has a shorter and distinct C-terminus compared to isoform 1.
      Source sequence(s)
      AC163748
      Conserved Domains (5) summary
      smart00053
      Location:6245
      DYNc; Dynamin, GTPase
      PHA03247
      Location:733832
      PHA03247; large tegument protein UL36; Provisional
      cd01256
      Location:514625
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:216502
      Dynamin_M; Dynamin central region
      pfam02212
      Location:646735
      GED; Dynamin GTPase effector domain
    7. NM_007871.2NP_031897.2  dynamin-2 isoform 3

      See identical proteins and their annotated locations for NP_031897.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks an alternate exon in the coding region compared to variant 1. The resulting protein (isoform 3) is shorter but has the same N- and C-termini compared to isoform 1.
      Source sequence(s)
      AA221527, AK005012, AK157844, BY275016, BY549643
      Consensus CDS
      CCDS57659.1
      UniProtKB/Swiss-Prot
      P39054
      Related
      ENSMUSP00000088616.7, ENSMUST00000091087.13
      Conserved Domains (5) summary
      smart00053
      Location:6245
      DYNc; Dynamin, GTPase
      PHA03247
      Location:733864
      PHA03247; large tegument protein UL36; Provisional
      cd01256
      Location:514625
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:216502
      Dynamin_M; Dynamin central region
      pfam02212
      Location:646735
      GED; Dynamin GTPase effector domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      21336167..21419055
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036154602.1XP_036010495.1  dynamin-2 isoform X7

      Conserved Domains (5) summary
      smart00053
      Location:6245
      DYNc; Dynamin, GTPase
      PHA03247
      Location:747846
      PHA03247; large tegument protein UL36; Provisional
      cd01256
      Location:530639
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:216498
      Dynamin_M; Dynamin central region
      pfam02212
      Location:661749
      GED; Dynamin GTPase effector domain
    2. XM_036154603.1XP_036010496.1  dynamin-2 isoform X10

      Conserved Domains (5) summary
      smart00053
      Location:6245
      DYNc; Dynamin, GTPase
      PHA03247
      Location:743842
      PHA03247; large tegument protein UL36; Provisional
      cd01256
      Location:524635
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:216498
      Dynamin_M; Dynamin central region
      pfam02212
      Location:657745
      GED; Dynamin GTPase effector domain
    3. XM_006509981.4XP_006510044.1  dynamin-2 isoform X13

      Conserved Domains (5) summary
      smart00053
      Location:6245
      DYNc; Dynamin, GTPase
      PHA03247
      Location:737836
      PHA03247; large tegument protein UL36; Provisional
      cd01256
      Location:520629
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:216502
      Dynamin_M; Dynamin central region
      pfam02212
      Location:650739
      GED; Dynamin GTPase effector domain
    4. XM_006509976.4XP_006510039.1  dynamin-2 isoform X5

      Conserved Domains (5) summary
      smart00053
      Location:6245
      DYNc; Dynamin, GTPase
      PHA03247
      Location:743874
      PHA03247; large tegument protein UL36; Provisional
      cd01256
      Location:524635
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:216498
      Dynamin_M; Dynamin central region
      pfam02212
      Location:656745
      GED; Dynamin GTPase effector domain
    5. XM_017313127.3XP_017168616.1  dynamin-2 isoform X12

      Conserved Domains (5) summary
      smart00053
      Location:6245
      DYNc; Dynamin, GTPase
      PRK14951
      Location:741861
      PRK14951; DNA polymerase III subunits gamma and tau; Provisional
      cd01256
      Location:514625
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:216502
      Dynamin_M; Dynamin central region
      pfam02212
      Location:646735
      GED; Dynamin GTPase effector domain
    6. XM_036154600.1XP_036010493.1  dynamin-2 isoform X4

      Conserved Domains (5) summary
      smart00053
      Location:6245
      DYNc; Dynamin, GTPase
      PHA03247
      Location:743874
      PHA03247; large tegument protein UL36; Provisional
      cd01256
      Location:524635
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:216498
      Dynamin_M; Dynamin central region
      pfam02212
      Location:657745
      GED; Dynamin GTPase effector domain
    7. XM_036154601.1XP_036010494.1  dynamin-2 isoform X6

      Conserved Domains (5) summary
      smart00053
      Location:6245
      DYNc; Dynamin, GTPase
      PRK14951
      Location:751871
      PRK14951; DNA polymerase III subunits gamma and tau; Provisional
      cd01256
      Location:524635
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:216498
      Dynamin_M; Dynamin central region
      pfam02212
      Location:657745
      GED; Dynamin GTPase effector domain
    8. XM_006509980.4XP_006510043.1  dynamin-2 isoform X9

      Conserved Domains (5) summary
      smart00053
      Location:6245
      DYNc; Dynamin, GTPase
      PHA03247
      Location:733864
      PHA03247; large tegument protein UL36; Provisional
      cd01256
      Location:514625
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:216502
      Dynamin_M; Dynamin central region
      pfam02212
      Location:646735
      GED; Dynamin GTPase effector domain
    9. XM_017313128.3XP_017168617.1  dynamin-2 isoform X11

      Conserved Domains (5) summary
      smart00053
      Location:6245
      DYNc; Dynamin, GTPase
      PRK14951
      Location:741861
      PRK14951; DNA polymerase III subunits gamma and tau; Provisional
      cd01256
      Location:514625
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:216502
      Dynamin_M; Dynamin central region
      pfam02212
      Location:646735
      GED; Dynamin GTPase effector domain
    10. XM_006509973.3XP_006510036.1  dynamin-2 isoform X2

      Conserved Domains (5) summary
      smart00053
      Location:6245
      DYNc; Dynamin, GTPase
      PHA03247
      Location:747878
      PHA03247; large tegument protein UL36; Provisional
      cd01256
      Location:530639
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:216498
      Dynamin_M; Dynamin central region
      pfam02212
      Location:660749
      GED; Dynamin GTPase effector domain
    11. XM_006509979.3XP_006510042.1  dynamin-2 isoform X8

      Conserved Domains (5) summary
      smart00053
      Location:6245
      DYNc; Dynamin, GTPase
      PRK14951
      Location:745865
      PRK14951; DNA polymerase III subunits gamma and tau; Provisional
      cd01256
      Location:520629
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:216502
      Dynamin_M; Dynamin central region
      pfam02212
      Location:650739
      GED; Dynamin GTPase effector domain
    12. XM_006509974.3XP_006510037.1  dynamin-2 isoform X1

      Conserved Domains (5) summary
      smart00053
      Location:6245
      DYNc; Dynamin, GTPase
      PHA03247
      Location:747878
      PHA03247; large tegument protein UL36; Provisional
      cd01256
      Location:530639
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:216498
      Dynamin_M; Dynamin central region
      pfam02212
      Location:660749
      GED; Dynamin GTPase effector domain
    13. XM_036154599.1XP_036010492.1  dynamin-2 isoform X3

      Conserved Domains (5) summary
      smart00053
      Location:6245
      DYNc; Dynamin, GTPase
      PRK14951
      Location:755875
      PRK14951; DNA polymerase III subunits gamma and tau; Provisional
      cd01256
      Location:530639
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:216498
      Dynamin_M; Dynamin central region
      pfam02212
      Location:661749
      GED; Dynamin GTPase effector domain
    14. XM_036154604.1XP_036010497.1  dynamin-2 isoform X18

      Conserved Domains (2) summary
      smart00053
      Location:6245
      DYNc; Dynamin, GTPase
      pfam01031
      Location:216498
      Dynamin_M; Dynamin central region
    15. XM_030244046.2XP_030099906.1  dynamin-2 isoform X17

      Conserved Domains (5) summary
      PHA03247
      Location:575674
      PHA03247; large tegument protein UL36; Provisional
      cd01256
      Location:356467
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:58344
      Dynamin_M; Dynamin central region
      pfam02212
      Location:488577
      GED; Dynamin GTPase effector domain
      cl38985
      Location:187
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    16. XM_030244045.2XP_030099905.1  dynamin-2 isoform X16

      Conserved Domains (5) summary
      PHA03247
      Location:575706
      PHA03247; large tegument protein UL36; Provisional
      cd01256
      Location:356467
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:58344
      Dynamin_M; Dynamin central region
      pfam02212
      Location:488577
      GED; Dynamin GTPase effector domain
      cl38985
      Location:187
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    17. XM_030244043.2XP_030099903.1  dynamin-2 isoform X14

      Conserved Domains (5) summary
      PHA03247
      Location:589720
      PHA03247; large tegument protein UL36; Provisional
      cd01256
      Location:372481
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:58340
      Dynamin_M; Dynamin central region
      pfam02212
      Location:502591
      GED; Dynamin GTPase effector domain
      cl38985
      Location:187
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    18. XM_030244044.2XP_030099904.1  dynamin-2 isoform X15

      Conserved Domains (5) summary
      PHA03247
      Location:579710
      PHA03247; large tegument protein UL36; Provisional
      cd01256
      Location:362471
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:58344
      Dynamin_M; Dynamin central region
      pfam02212
      Location:492581
      GED; Dynamin GTPase effector domain
      cl38985
      Location:187
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    19. XM_036154605.1XP_036010498.1  dynamin-2 isoform X19

      Conserved Domains (4) summary
      PHA03247
      Location:341472
      PHA03247; large tegument protein UL36; Provisional
      cd01256
      Location:124233
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:192
      Dynamin_M; Dynamin central region
      pfam02212
      Location:255343
      GED; Dynamin GTPase effector domain
    20. XM_036154607.1XP_036010500.1  dynamin-2 isoform X21

      Conserved Domains (4) summary
      PRK14951
      Location:335455
      PRK14951; DNA polymerase III subunits gamma and tau; Provisional
      cd01256
      Location:108219
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:196
      Dynamin_M; Dynamin central region
      pfam02212
      Location:241329
      GED; Dynamin GTPase effector domain
    21. XM_036154606.1XP_036010499.1  dynamin-2 isoform X20

      Conserved Domains (4) summary
      PHA03247
      Location:331462
      PHA03247; large tegument protein UL36; Provisional
      cd01256
      Location:114223
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:196
      Dynamin_M; Dynamin central region
      pfam02212
      Location:245333
      GED; Dynamin GTPase effector domain
    22. XM_036154608.1XP_036010501.1  dynamin-2 isoform X22

      Conserved Domains (4) summary
      PHA03247
      Location:341440
      PHA03247; large tegument protein UL36; Provisional
      cd01256
      Location:124233
      PH_dynamin; Dynamin pleckstrin homology (PH) domain
      pfam01031
      Location:2106
      Dynamin_M; Dynamin central region
      pfam02212
      Location:255343
      GED; Dynamin GTPase effector domain

    RNA

    1. XR_001778793.3 RNA Sequence

    2. XR_003947776.2 RNA Sequence

    Support Center