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    CFAP90 cilia and flagella associated protein 90 [ Homo sapiens (human) ]

    Gene ID: 134121, updated on 17-Jun-2024

    Summary

    Official Symbol
    CFAP90provided by HGNC
    Official Full Name
    cilia and flagella associated protein 90provided by HGNC
    Primary source
    HGNC:HGNC:27028
    See related
    Ensembl:ENSG00000215217 AllianceGenome:HGNC:27028
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    C5orf49
    Summary
    Located in ciliary basal body. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in testis (RPKM 8.1), lung (RPKM 2.5) and 5 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See CFAP90 in Genome Data Viewer
    Location:
    5p15.31
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (7830378..7851133, complement)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (7769514..7790256, complement)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (7830491..7851246, complement)

    Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107986403 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:7394801-7395566 Neighboring gene long intergenic non-protein coding RNA 2142 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:7395567-7396332 Neighboring gene uncharacterized LOC105374646 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:7420020-7420743 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:7420744-7421468 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr5:7422307-7423176 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:7424665-7425194 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:7425195-7425722 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr5:7427184-7427875 Neighboring gene adenylate cyclase 2 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:7480982-7481482 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:7481483-7481983 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:7515349-7515849 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:7526205-7526704 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:7596934-7597448 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:7597449-7597963 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr5:7663263-7663836 Neighboring gene OCT4-NANOG-H3K4me1 hESC enhancer GRCh37_chr5:7663837-7664409 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr5:7667125-7668324 Neighboring gene ReSE screen-validated silencer GRCh37_chr5:7683613-7683799 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22344 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22345 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22346 Neighboring gene Sharpr-MPRA regulatory region 1766 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:7815313-7815850 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:7816087-7816815 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:7816816-7817543 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15904 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15905 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15906 Neighboring gene FAST kinase domains 3 Neighboring gene uncharacterized LOC124900936 Neighboring gene 5-methyltetrahydrofolate-homocysteine methyltransferase reductase

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    cilia- and flagella-associated protein 90
    Names
    uncharacterized protein C5orf49

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001089584.3NP_001083053.1  cilia- and flagella-associated protein 90

      See identical proteins and their annotated locations for NP_001083053.1

      Status: VALIDATED

      Source sequence(s)
      AC010346, BC062569
      Consensus CDS
      CCDS43300.1
      UniProtKB/Swiss-Prot
      A4QMS7
      UniProtKB/TrEMBL
      D6RHK3
      Related
      ENSP00000382708.2, ENST00000399810.7
      Conserved Domains (1) summary
      pfam15074
      Location:42131
      DUF4541; Domain of unknown function (DUF4541)

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

      Range
      7830378..7851133 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011513963.3XP_011512265.1  cilia- and flagella-associated protein 90 isoform X1

      Conserved Domains (1) summary
      pfam15074
      Location:1899
      DUF4541; Domain of unknown function (DUF4541)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060929.1 Alternate T2T-CHM13v2.0

      Range
      7769514..7790256 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054351610.1XP_054207585.1  cilia- and flagella-associated protein 90 isoform X1