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    Dmwd dystrophia myotonica-containing WD repeat motif [ Mus musculus (house mouse) ]

    Gene ID: 13401, updated on 26-Sep-2022

    Summary

    Official Symbol
    Dmwdprovided by MGI
    Official Full Name
    dystrophia myotonica-containing WD repeat motifprovided by MGI
    Primary source
    MGI:MGI:94907
    See related
    Ensembl:ENSMUSG00000030410 AllianceGenome:MGI:94907
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Dm9; DMR-N9
    Summary
    Predicted to be located in cell projection and nucleus. Is expressed in several structures, including brain; sensory organ; skeletal muscle; testis; and trophectoderm. Orthologous to human DMWD (DM1 locus, WD repeat containing). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in ovary adult (RPKM 66.7), adrenal adult (RPKM 65.5) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Dmwd in Genome Data Viewer
    Location:
    7 A3; 7 9.46 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (18810002..18816701)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (19076112..19082778)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene symplekin Neighboring gene radial spoke head 6 homolog A (Chlamydomonas) Neighboring gene microRNA 3100 Neighboring gene dystrophia myotonica-protein kinase Neighboring gene meiosis initiator Neighboring gene sine oculis-related homeobox 5

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC37679, MGC115779

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cellular_component ND
    No biological Data available
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    dystrophia myotonica WD repeat-containing protein
    Names
    dystrophia myotonica linked gene, N9
    dystrophia myotonica-containing WD repeat motif protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001374607.1NP_001361536.1  dystrophia myotonica WD repeat-containing protein isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC170864
      Consensus CDS
      CCDS90169.1
      UniProtKB/TrEMBL
      E9Q6J8
      Related
      ENSMUSP00000104119.2, ENSMUST00000108479.2
    2. NM_010058.2NP_034188.2  dystrophia myotonica WD repeat-containing protein isoform 1

      See identical proteins and their annotated locations for NP_034188.2

      Status: VALIDATED

      Source sequence(s)
      AC170864, AK086899, BC089027, CF169673
      Consensus CDS
      CCDS20888.2
      UniProtKB/Swiss-Prot
      E9QLY4, Q08274
      UniProtKB/TrEMBL
      Q5HZG7
      Related
      ENSMUSP00000032570.8, ENSMUST00000032570.14
      Conserved Domains (3) summary
      COG2319
      Location:98376
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:214254
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:281375
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      18810002..18816701
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006539524.5XP_006539587.1  dystrophia myotonica WD repeat-containing protein isoform X1

      Conserved Domains (2) summary
      sd00039
      Location:190230
      7WD40; WD40 repeat [structural motif]
      cl29593
      Location:257351
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...