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    SLX4IP SLX4 interacting protein [ Homo sapiens (human) ]

    Gene ID: 128710, updated on 17-Jun-2024

    Summary

    Official Symbol
    SLX4IPprovided by HGNC
    Official Full Name
    SLX4 interacting proteinprovided by HGNC
    Primary source
    HGNC:HGNC:16225
    See related
    Ensembl:ENSG00000149346 MIM:615958; AllianceGenome:HGNC:16225
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    C20orf94; bA204H22.1; bA254M13.1; dJ1099D15.3
    Expression
    Ubiquitous expression in skin (RPKM 1.0), testis (RPKM 0.9) and 25 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See SLX4IP in Genome Data Viewer
    Location:
    20p12.2
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 20 NC_000020.11 (10435305..10628030)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 20 NC_060944.1 (10478114..10671152)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (10415953..10608678)

    Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene SDA1 domain containing 1 pseudogene 2 Neighboring gene uncharacterized LOC128706665 Neighboring gene uncharacterized LOC128706666 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr20:10399946-10401145 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12671 Neighboring gene NANOG hESC enhancer GRCh37_chr20:10412265-10412766 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17542 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17543 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17544 Neighboring gene MKKS centrosomal shuttling protein Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr20:10447220-10447919 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17545 Neighboring gene Sharpr-MPRA regulatory region 2397 Neighboring gene Sharpr-MPRA regulatory region 8388 Neighboring gene Sharpr-MPRA regulatory region 5326 Neighboring gene H3K27ac hESC enhancer GRCh37_chr20:10529678-10530178 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17547 Neighboring gene Sharpr-MPRA regulatory region 6934 Neighboring gene Sharpr-MPRA regulatory region 11569 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr20:10578661-10579860 Neighboring gene DNAJC9 pseudogene 1 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:10617378-10618174 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:10618175-10618971 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:10621299-10622074 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:10622075-10622850 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12672 Neighboring gene Sharpr-MPRA regulatory region 15707 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12673 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12674 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12675 Neighboring gene microRNA 6870 Neighboring gene jagged canonical Notch ligand 1 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr20:10686119-10687318 Neighboring gene long intergenic non-protein coding RNA 1752

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    HIV-1 interactions

    Protein interactions

    Protein Gene Interaction Pubs
    Vpr vpr HIV-1 Vpr interacts with TSPYL1 and C20orf94 subunits of the SLX4 complex in Vpr-expressing THP-1 cells PubMed

    Go to the HIV-1, Human Interaction Database

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001009608.3NP_001009608.1  protein SLX4IP

      See identical proteins and their annotated locations for NP_001009608.1

      Status: VALIDATED

      Source sequence(s)
      AL035456, BC026094, CA416447
      Consensus CDS
      CCDS33439.1
      UniProtKB/Swiss-Prot
      Q05CG2, Q05CT9, Q5VYV7
      Related
      ENSP00000335557.5, ENST00000334534.10
      Conserved Domains (1) summary
      pfam15744
      Location:10366
      UPF0492; Uncharacterized protein family UPF0492

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000020.11 Reference GRCh38.p14 Primary Assembly

      Range
      10435305..10628030
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060944.1 Alternate T2T-CHM13v2.0

      Range
      10478114..10671152
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054322966.1XP_054178941.1  protein SLX4IP isoform X1

    2. XM_054322967.1XP_054178942.1  protein SLX4IP isoform X2