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    Cnbp cellular nucleic acid binding protein [ Mus musculus (house mouse) ]

    Gene ID: 12785, updated on 31-Jan-2019

    Summary

    Official Symbol
    Cnbpprovided by MGI
    Official Full Name
    cellular nucleic acid binding proteinprovided by MGI
    Primary source
    MGI:MGI:88431
    See related
    Ensembl:ENSMUSG00000030057
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Znf9; Cnbp1; AA408710
    Expression
    Ubiquitous expression in placenta adult (RPKM 105.5), liver E14 (RPKM 104.7) and 28 other tissues See more
    Orthologs

    Genomic context

    See Cnbp in Genome Data Viewer
    Location:
    6; 6 D1
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 6 NC_000072.6 (87842615..87851106, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (87792609..87801100, complement)

    Chromosome 6 - NC_000072.6Genomic Context describing neighboring genes Neighboring gene RAB43, member RAS oncogene family Neighboring gene ISY1 splicing factor homolog Neighboring gene coatomer protein complex, subunit gamma 1 Neighboring gene 5-hydroxymethylcytosine (hmC) binding, ES cell specific Neighboring gene eukaryotic translation elongation factor 1 alpha 1 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    DNA-binding transcription repressor activity, RNA polymerase II-specific ISO
    Inferred from Sequence Orthology
    more info
     
    RNA polymerase II regulatory region sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    single-stranded DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    single-stranded RNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    NOT nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    cellular nucleic acid-binding protein
    Names
    cellular nucleic acid binding protein 1
    zinc finger protein 9

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109745.1NP_001103215.1  cellular nucleic acid-binding protein isoform 2

      See identical proteins and their annotated locations for NP_001103215.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) has an alternate splice site in the CDS, as compared to variant 1. The resulting isoform (2) lacks an internal segment and has identical N- and C-termini, as compared to isoform 1.
      Source sequence(s)
      AK078427, AK144740, AK159810, CJ088264
      UniProtKB/Swiss-Prot
      P53996
      UniProtKB/TrEMBL
      Q3U5V2, Q5QJQ9
      Conserved Domains (1) summary
      cl26705
      Location:47165
      AIR1; Arginine methyltransferase-interacting protein, contains RING Zn-finger [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]
    2. NM_001109746.1NP_001103216.1  cellular nucleic acid-binding protein isoform 3

      See identical proteins and their annotated locations for NP_001103216.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) has two alternate splice sites in the CDS, as compared to variant 1. The resulting isoform (3) differs in the middle region and has identical N- and C-termini, as compared to isoform 1.
      Source sequence(s)
      AK144740, AK151961, CJ088264
      Consensus CDS
      CCDS85092.1
      UniProtKB/TrEMBL
      Q3U935, Q5QJQ9
      Related
      ENSMUSP00000109249.2, ENSMUST00000113619.7
      Conserved Domains (1) summary
      cl26705
      Location:47164
      AIR1; Arginine methyltransferase-interacting protein, contains RING Zn-finger [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]
    3. NM_001347325.1NP_001334254.1  cellular nucleic acid-binding protein isoform 4

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) has an alternate splice site in the CDS, as compared to variant 1. The resulting isoform (4) lacks one amino acid, as compared to isoform 1.
      Source sequence(s)
      AK075760, AK144740, AK147157, CJ088264
      Consensus CDS
      CCDS85091.1
      UniProtKB/Swiss-Prot
      P53996
      UniProtKB/TrEMBL
      Q3ULK8, Q5QJQ9
      Conserved Domains (1) summary
      cl26705
      Location:54171
      AIR1; Arginine methyltransferase-interacting protein, contains RING Zn-finger [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]
    4. NM_001355195.1NP_001342124.1  cellular nucleic acid-binding protein isoform 5

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) has multiple alternate splice sites in the CDS, as compared to variant 1. The resulting isoform (5) lacks an internal segment and has identical N- and C-termini, as compared to isoform 1. Isoforms 2 and 5 are the same length but have distinct sequences.
      Source sequence(s)
      AK144740, AK147157, CJ088264
      Conserved Domains (1) summary
      cl26705
      Location:48165
      AIR1; Arginine methyltransferase-interacting protein, contains RING Zn-finger [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]
    5. NM_013493.3NP_038521.1  cellular nucleic acid-binding protein isoform 1

      See identical proteins and their annotated locations for NP_038521.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (1).
      Source sequence(s)
      AK144740, BC058723, CJ088264
      Consensus CDS
      CCDS51841.1
      UniProtKB/Swiss-Prot
      P53996
      UniProtKB/TrEMBL
      Q5QJQ9
      Related
      ENSMUSP00000032138.8, ENSMUST00000032138.14
      Conserved Domains (1) summary
      cl26705
      Location:54172
      AIR1; Arginine methyltransferase-interacting protein, contains RING Zn-finger [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000072.6 Reference GRCm38.p4 C57BL/6J

      Range
      87842615..87851106 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006505479.1XP_006505542.1  cellular nucleic acid-binding protein isoform X1

      Related
      ENSMUSP00000145274.1, ENSMUST00000204653.2
      Conserved Domains (1) summary
      cl26705
      Location:54171
      AIR1; Arginine methyltransferase-interacting protein, contains RING Zn-finger [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]
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