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    GOLT1A golgi transport 1A [ Homo sapiens (human) ]

    Gene ID: 127845, updated on 5-Mar-2024

    Summary

    Official Symbol
    GOLT1Aprovided by HGNC
    Official Full Name
    golgi transport 1Aprovided by HGNC
    Primary source
    HGNC:HGNC:24766
    See related
    Ensembl:ENSG00000174567 MIM:620633; AllianceGenome:HGNC:24766
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    GOT1; GOT1B; hGOT1b; CGI-141; YMR292W; HMFN1187
    Summary
    Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Located in Golgi apparatus subcompartment; endoplasmic reticulum; and nuclear envelope. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in liver (RPKM 34.0), duodenum (RPKM 16.2) and 5 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See GOLT1A in Genome Data Viewer
    Location:
    1q32.1
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (204198163..204213988, complement)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (203462758..203478572, complement)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (204167291..204183116, complement)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene REN promoter and enhancer region Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:204147944-204148444 Neighboring gene renin Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2359 Neighboring gene tripartite motif containing 60 pseudogene Neighboring gene KiSS-1 metastasis suppressor Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:204182987-204183643 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:204191229-204191730 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:204191731-204192230 Neighboring gene pleckstrin homology domain containing A6 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:204222775-204223276 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:204223277-204223776 Neighboring gene HNF1 motif-containing MPRA enhancer 91/92 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:204244227-204245062 Neighboring gene ReSE screen-validated silencer GRCh37_chr1:204251843-204252046 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:204252631-204253132 Neighboring gene H3K27ac hESC enhancer GRCh37_chr1:204253133-204253632 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:204264456-204265347 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:204273055-204273675 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:204291013-204291512 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr1:204305671-204306454 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:204307239-204308022 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:204309736-204310344 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:204317722-204318460 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:204326340-204327267 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:204327268-204328194 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:204328310-204328945 Neighboring gene ribosomal protein L21 pseudogene 19 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:204331933-204332486 Neighboring gene long intergenic non-protein coding RNA 628

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • FLJ42654, MGC62027

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in retrograde transport, endosome to Golgi IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in Golgi cis cisterna IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nuclear envelope IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in trans-Golgi network IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    vesicle transport protein GOT1A

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_198447.2NP_940849.1  vesicle transport protein GOT1A

      See identical proteins and their annotated locations for NP_940849.1

      Status: VALIDATED

      Source sequence(s)
      AK124645
      Consensus CDS
      CCDS1443.1
      UniProtKB/Swiss-Prot
      Q6ZVE7
      Related
      ENSP00000308535.3, ENST00000308302.4
      Conserved Domains (1) summary
      cl02130
      Location:4109
      Got1; Got1/Sft2-like family

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

      Range
      204198163..204213988 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017000314.2XP_016855803.1  vesicle transport protein GOT1A isoform X1

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060925.1 Alternate T2T-CHM13v2.0

      Range
      203462758..203478572 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054334405.1XP_054190380.1  vesicle transport protein GOT1A isoform X1