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    Cmas cytidine monophospho-N-acetylneuraminic acid synthetase [ Mus musculus (house mouse) ]

    Gene ID: 12764, updated on 5-Aug-2018

    Summary

    Official Symbol
    Cmasprovided by MGI
    Official Full Name
    cytidine monophospho-N-acetylneuraminic acid synthetaseprovided by MGI
    Primary source
    MGI:MGI:1337124
    See related
    Ensembl:ENSMUSG00000030282 Vega:OTTMUSG00000023787
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AW208911; CMPNeu5Ac; D6Bwg0250e
    Expression
    Ubiquitous expression in liver E14 (RPKM 52.8), liver E14.5 (RPKM 43.2) and 28 other tissues See more
    Orthologs

    Genomic context

    See Cmas in Genome Data Viewer
    Location:
    6 G2; 6 74.66 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 6 NC_000072.6 (142756686..142775714)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (142705206..142724234)

    Chromosome 6 - NC_000072.6Genomic Context describing neighboring genes Neighboring gene potassium inwardly-rectifying channel, subfamily J, member 8 Neighboring gene RIKEN cDNA 5330439B14 gene Neighboring gene ATP-binding cassette, sub-family C (CFTR/MRP), member 9 Neighboring gene predicted gene, 46980 Neighboring gene predicted gene, 46981 Neighboring gene sulfotransferase family 6B, member 2 Neighboring gene predicted gene 7457 Neighboring gene ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    N-acylneuraminate cytidylyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    N-acylneuraminate cytidylyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    nucleotidyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    CMP-N-acetylneuraminate biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Component Evidence Code Pubs
    nucleus ISO
    Inferred from Sequence Orthology
    more info
    PubMed 

    General protein information

    Preferred Names
    N-acylneuraminate cytidylyltransferase
    Names
    CMP-N-acetylneuraminic acid synthase
    CMP-N-acetylneuraminic acid synthetase
    CMP-Neu5Ac synthase
    CMP-NeuNAc synthase
    CMP-NeuNAc synthetase
    CMP-sialic acid synthetase
    NP_034038.2

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009908.2NP_034038.2  N-acylneuraminate cytidylyltransferase

      See identical proteins and their annotated locations for NP_034038.2

      Status: VALIDATED

      Source sequence(s)
      AK155730, BQ033546, CJ161865
      Consensus CDS
      CCDS20687.1
      UniProtKB/Swiss-Prot
      Q99KK2
      UniProtKB/TrEMBL
      A0A0R4J0B4
      Related
      ENSMUSP00000032419.8, OTTMUSP00000028116, ENSMUST00000032419.8, OTTMUST00000058121
      Conserved Domains (2) summary
      cd02513
      Location:42257
      CMP-NeuAc_Synthase; CMP-NeuAc_Synthase activates N-acetylneuraminic acid by adding CMP moiety
      cl21460
      Location:268419
      HAD_like; Haloacid Dehalogenase-like Hydrolases

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000072.6 Reference GRCm38.p4 C57BL/6J

      Range
      142756686..142775714
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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