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    Cit citron [ Mus musculus (house mouse) ]

    Gene ID: 12704, updated on 5-Sep-2021

    Summary

    Official Symbol
    Citprovided by MGI
    Official Full Name
    citronprovided by MGI
    Primary source
    MGI:MGI:105313
    See related
    Ensembl:ENSMUSG00000029516
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    CRIK; Cit-; Cit-k; CRIK-SK; C030025P15Rik
    Expression
    Broad expression in cortex adult (RPKM 9.3), frontal lobe adult (RPKM 8.3) and 24 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Cit in Genome Data Viewer
    Location:
    5; 5 F
    Exon count:
    53
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (115983284..116147012)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (115845224..116008953)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (116295665..116456352)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene BICD family like cargo adaptor 1 Neighboring gene ribosomal protein L29 Neighboring gene predicted gene, 42008 Neighboring gene predicted gene, 36185 Neighboring gene protein kinase, AMP-activated, beta 1 non-catalytic subunit Neighboring gene predicted gene 13842

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables PDZ domain binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables SH3 domain binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein serine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables protein serine/threonine kinase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein serine/threonine kinase activity TAS
    Traceable Author Statement
    more info
     
    enables protein serine/threonine kinase inhibitor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables scaffold protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables transcription coactivator binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in actomyosin structure organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cell division IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cytokinesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within dendrite development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in generation of neurons IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within metaphase/anaphase transition of mitotic cell cycle IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in mitotic cell cycle IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in mitotic cytokinesis ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within mitotic sister chromatid segregation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within negative regulation of dendrite morphogenesis IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in negative regulation of hippo signaling ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within negative regulation of neuron differentiation ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    acts_upstream_of_or_within nervous system development IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in neuron apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in peptidyl-threonine phosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of cytokinesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within spermatogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in actin cytoskeleton IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol TAS
    Traceable Author Statement
    more info
     
    located_in ruffle IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in vacuole IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    citron Rho-interacting kinase
    Names
    citron kinase
    citron-N
    rho-interacting, serine/threonine-protein kinase 21
    NP_031734.3
    XP_006530193.1
    XP_006530194.1
    XP_006530195.1
    XP_006530196.1
    XP_006530197.1
    XP_006530198.1
    XP_006530199.1
    XP_006530200.1
    XP_006530201.1
    XP_006530202.1
    XP_006530203.1
    XP_006530204.1
    XP_006530205.1
    XP_006530206.1
    XP_006530208.1
    XP_006530209.1
    XP_006530210.1
    XP_006530212.1
    XP_006530213.1
    XP_006530214.1
    XP_006530215.1
    XP_006530216.1
    XP_011246465.1
    XP_017176130.1
    XP_017176132.1
    XP_017176133.1
    XP_017176134.1
    XP_017176135.1
    XP_030109958.1
    XP_030109959.1
    XP_030109960.1
    XP_036020657.1
    XP_036020658.1
    XP_036020659.1
    XP_036020660.1
    XP_036020661.1
    XP_036020662.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_007708.3NP_031734.3  citron Rho-interacting kinase

      See identical proteins and their annotated locations for NP_031734.3

      Status: VALIDATED

      Source sequence(s)
      AC115795, AC162461
      Consensus CDS
      CCDS19597.1
      UniProtKB/TrEMBL
      E9QL53
      Related
      ENSMUSP00000062049.9, ENSMUST00000051704.15
      Conserved Domains (5) summary
      smart00036
      Location:16191915
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      smart00233
      Location:14701589
      PH; Pleckstrin homology domain
      COG1196
      Location:4731319
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00029
      Location:13891437
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd05601
      Location:96421
      STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      115983284..116147012
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006530131.3XP_006530194.1  citron Rho-interacting kinase isoform X1

      See identical proteins and their annotated locations for XP_006530194.1

      Conserved Domains (5) summary
      smart00036
      Location:16871983
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      smart00233
      Location:15231642
      PH; Pleckstrin homology domain
      COG1196
      Location:4731372
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00029
      Location:14421490
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd05601
      Location:96421
      STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
    2. XM_030254099.2XP_030109959.1  citron Rho-interacting kinase isoform X8

      Conserved Domains (5) summary
      smart00036
      Location:16581954
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      smart00233
      Location:14941613
      PH; Pleckstrin homology domain
      COG1196
      Location:4731343
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00029
      Location:14131461
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd05601
      Location:96421
      STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
    3. XM_006530146.4XP_006530209.1  citron Rho-interacting kinase isoform X17

      Conserved Domains (5) summary
      smart00233
      Location:15231642
      PH; Pleckstrin homology domain
      COG1196
      Location:4731372
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00029
      Location:14421490
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd05601
      Location:96421
      STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
      cl02434
      Location:16871743
      CNH; CNH domain
    4. XM_036164765.1XP_036020658.1  citron Rho-interacting kinase isoform X18

      Conserved Domains (5) summary
      COG1196
      Location:4731357
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd05601
      Location:96421
      STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
      pfam00169
      Location:15081627
      PH; PH domain
      cd20814
      Location:14231478
      CRIK; protein kinase C conserved region 1 (C1 domain) found in citron Rho-interacting kinase (CRIK) and similar proteins
      cl02434
      Location:16721728
      CNH; CNH domain
    5. XM_006530130.5XP_006530193.1  citron Rho-interacting kinase isoform X1

      See identical proteins and their annotated locations for XP_006530193.1

      Conserved Domains (5) summary
      smart00036
      Location:16871983
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      smart00233
      Location:15231642
      PH; Pleckstrin homology domain
      COG1196
      Location:4731372
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00029
      Location:14421490
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd05601
      Location:96421
      STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
    6. XM_006530134.5XP_006530197.1  citron Rho-interacting kinase isoform X2

      Conserved Domains (5) summary
      smart00036
      Location:16871983
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      smart00233
      Location:15231642
      PH; Pleckstrin homology domain
      COG1196
      Location:4731372
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00029
      Location:14421490
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd05601
      Location:96421
      STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
    7. XM_006530137.5XP_006530200.1  citron Rho-interacting kinase isoform X5

      Conserved Domains (5) summary
      smart00036
      Location:16721968
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      smart00233
      Location:15231642
      PH; Pleckstrin homology domain
      COG1196
      Location:4731372
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00029
      Location:14421490
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd05601
      Location:96421
      STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
    8. XM_036164764.1XP_036020657.1  citron Rho-interacting kinase isoform X6

      Conserved Domains (5) summary
      smart00036
      Location:16721968
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      COG1196
      Location:4731372
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd05601
      Location:96421
      STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
      pfam00169
      Location:15231642
      PH; PH domain
      cd20814
      Location:14381493
      CRIK; protein kinase C conserved region 1 (C1 domain) found in citron Rho-interacting kinase (CRIK) and similar proteins
    9. XM_006530136.5XP_006530199.1  citron Rho-interacting kinase isoform X4

      Conserved Domains (5) summary
      smart00036
      Location:16721968
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      smart00233
      Location:15081627
      PH; Pleckstrin homology domain
      COG1196
      Location:4731357
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00029
      Location:14271475
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd05601
      Location:96421
      STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
    10. XM_030254100.2XP_030109960.1  citron Rho-interacting kinase isoform X9

      Conserved Domains (5) summary
      smart00036
      Location:16571953
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      smart00233
      Location:15081627
      PH; Pleckstrin homology domain
      COG1196
      Location:4731357
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00029
      Location:14271475
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd05601
      Location:96421
      STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
    11. XM_006530135.5XP_006530198.1  citron Rho-interacting kinase isoform X3

      Conserved Domains (5) summary
      smart00036
      Location:16781974
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      smart00233
      Location:15141633
      PH; Pleckstrin homology domain
      COG1196
      Location:4731363
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00029
      Location:14331481
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd05601
      Location:96421
      STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
    12. XM_030254098.1XP_030109958.1  citron Rho-interacting kinase isoform X7

      Conserved Domains (5) summary
      smart00036
      Location:16631959
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      smart00233
      Location:14991618
      PH; Pleckstrin homology domain
      COG1196
      Location:4731348
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00029
      Location:14181466
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd05601
      Location:96421
      STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
    13. XM_006530139.5XP_006530202.1  citron Rho-interacting kinase isoform X10

      Conserved Domains (5) summary
      smart00036
      Location:16451941
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      smart00233
      Location:14811600
      PH; Pleckstrin homology domain
      COG1196
      Location:5551330
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00029
      Location:14001448
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd05601
      Location:96421
      STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
    14. XM_006530138.5XP_006530201.1  citron Rho-interacting kinase isoform X8

      Conserved Domains (5) summary
      smart00036
      Location:16581954
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      smart00233
      Location:14941613
      PH; Pleckstrin homology domain
      COG1196
      Location:4731343
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00029
      Location:14131461
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd05601
      Location:96421
      STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
    15. XM_006530140.4XP_006530203.1  citron Rho-interacting kinase isoform X11

      UniProtKB/TrEMBL
      D3YU89
      Related
      ENSMUSP00000099620.4, ENSMUST00000102560.7
      Conserved Domains (5) summary
      smart00036
      Location:16341930
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      smart00233
      Location:14851604
      PH; Pleckstrin homology domain
      COG1196
      Location:4731334
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00029
      Location:14041452
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd05601
      Location:96421
      STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
    16. XM_006530141.4XP_006530204.1  citron Rho-interacting kinase isoform X12

      See identical proteins and their annotated locations for XP_006530204.1

      UniProtKB/TrEMBL
      E9QL53
      Conserved Domains (5) summary
      smart00036
      Location:16191915
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      smart00233
      Location:14701589
      PH; Pleckstrin homology domain
      COG1196
      Location:4731319
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00029
      Location:13891437
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd05601
      Location:96421
      STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
    17. XM_006530143.4XP_006530206.1  citron Rho-interacting kinase isoform X14

      UniProtKB/TrEMBL
      D3Z1U0
      Related
      ENSMUSP00000107639.3, ENSMUST00000112008.9
      Conserved Domains (5) summary
      smart00036
      Location:15921888
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      smart00233
      Location:14431562
      PH; Pleckstrin homology domain
      COG1196
      Location:4551292
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00029
      Location:13621410
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd05601
      Location:96421
      STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
    18. XM_006530145.4XP_006530208.1  citron Rho-interacting kinase isoform X15

      UniProtKB/TrEMBL
      F6SBR5
      Related
      ENSMUSP00000115802.3, ENSMUST00000141101.5
      Conserved Domains (5) summary
      smart00036
      Location:15771873
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      smart00233
      Location:14281547
      PH; Pleckstrin homology domain
      COG1196
      Location:4801282
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00029
      Location:13471395
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd05601
      Location:96421
      STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
    19. XM_011248163.3XP_011246465.1  citron Rho-interacting kinase isoform X16

      Conserved Domains (5) summary
      smart00036
      Location:15771873
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      smart00233
      Location:14281547
      PH; Pleckstrin homology domain
      COG1196
      Location:4801282
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00029
      Location:13471395
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd05601
      Location:96421
      STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
    20. XM_006530142.4XP_006530205.1  citron Rho-interacting kinase isoform X13

      Conserved Domains (5) summary
      smart00036
      Location:16871983
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      smart00233
      Location:15231642
      PH; Pleckstrin homology domain
      COG1196
      Location:4731372
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00029
      Location:14421490
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd05601
      Location:96421
      STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
    21. XM_006530133.4XP_006530196.1  citron Rho-interacting kinase isoform X1

      See identical proteins and their annotated locations for XP_006530196.1

      Conserved Domains (5) summary
      smart00036
      Location:16871983
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      smart00233
      Location:15231642
      PH; Pleckstrin homology domain
      COG1196
      Location:4731372
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00029
      Location:14421490
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd05601
      Location:96421
      STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
    22. XM_036164766.1XP_036020659.1  citron Rho-interacting kinase isoform X19

      Conserved Domains (5) summary
      PTZ00449
      Location:15541645
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      smart00036
      Location:12421538
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      COG1196
      Location:28927
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam00169
      Location:10781197
      PH; PH domain
      cd20814
      Location:9931048
      CRIK; protein kinase C conserved region 1 (C1 domain) found in citron Rho-interacting kinase (CRIK) and similar proteins
    23. XM_006530132.5XP_006530195.1  citron Rho-interacting kinase isoform X1

      See identical proteins and their annotated locations for XP_006530195.1

      Conserved Domains (5) summary
      smart00036
      Location:16871983
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      smart00233
      Location:15231642
      PH; Pleckstrin homology domain
      COG1196
      Location:4731372
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00029
      Location:14421490
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      cd05601
      Location:96421
      STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
    24. XM_006530150.5XP_006530213.1  citron Rho-interacting kinase isoform X22

      Conserved Domains (5) summary
      PTZ00449
      Location:15331624
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      smart00036
      Location:12211517
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      smart00233
      Location:10571176
      PH; Pleckstrin homology domain
      COG1196
      Location:7906
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00029
      Location:9761024
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    25. XM_036164768.1XP_036020661.1  citron Rho-interacting kinase isoform X24

      Conserved Domains (5) summary
      PTZ00449
      Location:15041595
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      smart00036
      Location:11921488
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      COG1196
      Location:7877
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam00169
      Location:10281147
      PH; PH domain
      cd20814
      Location:943998
      CRIK; protein kinase C conserved region 1 (C1 domain) found in citron Rho-interacting kinase (CRIK) and similar proteins
    26. XM_006530149.5XP_006530212.1  citron Rho-interacting kinase isoform X21

      Conserved Domains (5) summary
      PTZ00449
      Location:15411632
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      smart00036
      Location:12291525
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      smart00233
      Location:10651184
      PH; Pleckstrin homology domain
      COG1196
      Location:15914
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00029
      Location:9841032
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    27. XM_017320644.3XP_017176133.1  citron Rho-interacting kinase isoform X26

      Conserved Domains (5) summary
      PTZ00449
      Location:14991590
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      smart00036
      Location:11871483
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      smart00233
      Location:10231142
      PH; Pleckstrin homology domain
      COG1196
      Location:97872
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00029
      Location:942990
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    28. XM_017320645.3XP_017176134.1  citron Rho-interacting kinase isoform X27

      Conserved Domains (5) summary
      PTZ00449
      Location:14901581
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      smart00036
      Location:11781474
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      smart00233
      Location:10141133
      PH; Pleckstrin homology domain
      COG1196
      Location:5863
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00029
      Location:933981
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    29. XM_017320641.3XP_017176130.1  citron Rho-interacting kinase isoform X23

      Conserved Domains (5) summary
      PTZ00449
      Location:15121603
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      smart00036
      Location:12001496
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      smart00233
      Location:10361155
      PH; Pleckstrin homology domain
      COG1196
      Location:15885
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00029
      Location:9551003
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    30. XM_036164769.1XP_036020662.1  citron Rho-interacting kinase isoform X29

      Conserved Domains (5) summary
      PTZ00449
      Location:14821573
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      smart00036
      Location:11701466
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      COG1196
      Location:15870
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam00169
      Location:10211140
      PH; PH domain
      cd20814
      Location:936991
      CRIK; protein kinase C conserved region 1 (C1 domain) found in citron Rho-interacting kinase (CRIK) and similar proteins
    31. XM_017320643.3XP_017176132.1  citron Rho-interacting kinase isoform X25

      Conserved Domains (5) summary
      PTZ00449
      Location:15031594
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      smart00036
      Location:11911487
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      smart00233
      Location:10271146
      PH; Pleckstrin homology domain
      COG1196
      Location:15876
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00029
      Location:946994
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    32. XM_017320646.3XP_017176135.1  citron Rho-interacting kinase isoform X28

      Conserved Domains (5) summary
      PTZ00449
      Location:14881579
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      smart00036
      Location:11761472
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      smart00233
      Location:10121131
      PH; Pleckstrin homology domain
      COG1196
      Location:15861
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00029
      Location:931979
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    33. XM_006530151.5XP_006530214.1  citron Rho-interacting kinase isoform X30

      See identical proteins and their annotated locations for XP_006530214.1

      UniProtKB/Swiss-Prot
      P49025
      Conserved Domains (5) summary
      PTZ00449
      Location:14731564
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      smart00036
      Location:11611457
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      smart00233
      Location:10121131
      PH; Pleckstrin homology domain
      COG1196
      Location:15861
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00029
      Location:931979
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    34. XM_006530147.2XP_006530210.1  citron Rho-interacting kinase isoform X19

      See identical proteins and their annotated locations for XP_006530210.1

      Conserved Domains (5) summary
      PTZ00449
      Location:15541645
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      smart00036
      Location:12421538
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      COG1196
      Location:28927
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam00169
      Location:10781197
      PH; PH domain
      cd20814
      Location:9931048
      CRIK; protein kinase C conserved region 1 (C1 domain) found in citron Rho-interacting kinase (CRIK) and similar proteins
    35. XM_036164767.1XP_036020660.1  citron Rho-interacting kinase isoform X20

      Conserved Domains (5) summary
      PTZ00449
      Location:15451636
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      smart00036
      Location:12331529
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      COG1196
      Location:28918
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam00169
      Location:10691188
      PH; PH domain
      cd20814
      Location:9841039
      CRIK; protein kinase C conserved region 1 (C1 domain) found in citron Rho-interacting kinase (CRIK) and similar proteins
    36. XM_006530152.2XP_006530215.1  citron Rho-interacting kinase isoform X31

      Conserved Domains (5) summary
      PTZ00449
      Location:11851276
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      smart00036
      Location:8731169
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      smart00233
      Location:709828
      PH; Pleckstrin homology domain
      COG1196
      Location:2580
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00029
      Location:628676
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    37. XM_006530153.1XP_006530216.1  citron Rho-interacting kinase isoform X32

      Related
      ENSMUST00000122877.8
      Conserved Domains (4) summary
      smart00036
      Location:8491145
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      smart00233
      Location:700819
      PH; Pleckstrin homology domain
      COG1196
      Location:2571
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00029
      Location:619667
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
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