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    Cirbp cold inducible RNA binding protein [ Mus musculus (house mouse) ]

    Gene ID: 12696, updated on 24-Jul-2021

    Summary

    Official Symbol
    Cirbpprovided by MGI
    Official Full Name
    cold inducible RNA binding proteinprovided by MGI
    Primary source
    MGI:MGI:893588
    See related
    Ensembl:ENSMUSG00000045193
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C; Cirp; R74941
    Expression
    Ubiquitous expression in CNS E14 (RPKM 77.5), whole brain E14.5 (RPKM 68.5) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Cirbp in Genome Data Viewer
    Location:
    10 C1; 10 39.72 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (80001824..80008620)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (80165990..80172786)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (79630586..79634398)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene calcium channel, voltage-dependent, beta subunit associated regulatory protein Neighboring gene ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit Neighboring gene midnolin Neighboring gene family with sequence similarity 174, member C Neighboring gene ephrin A2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables mRNA 3'-UTR binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables poly(U) RNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables small ribosomal subunit rRNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables translation repressor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasmic stress granule IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    part_of spliceosomal complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    cold-inducible RNA-binding protein
    Names
    A18 hnRNP
    glycine-rich RNA-binding protein CIRP

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001379421.1NP_001366350.1  cold-inducible RNA-binding protein isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC159999
      Conserved Domains (1) summary
      cd12449
      Location:685
      RRM_CIRBP_RBM3; RNA recognition motif (RRM) found in cold inducible RNA binding protein (CIRBP), RNA binding motif protein 3 (RBM3) and similar proteins
    2. NM_001379422.1NP_001366351.1  cold-inducible RNA-binding protein isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC159999
      Conserved Domains (1) summary
      cd12449
      Location:685
      RRM_CIRBP_RBM3; RNA recognition motif (RRM) found in cold inducible RNA binding protein (CIRBP), RNA binding motif protein 3 (RBM3) and similar proteins
    3. NM_001379423.1NP_001366352.1  cold-inducible RNA-binding protein isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC159999
      Conserved Domains (1) summary
      cd12449
      Location:685
      RRM_CIRBP_RBM3; RNA recognition motif (RRM) found in cold inducible RNA binding protein (CIRBP), RNA binding motif protein 3 (RBM3) and similar proteins
    4. NM_001379424.1NP_001366353.1  cold-inducible RNA-binding protein isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC159999
      Conserved Domains (1) summary
      cd12449
      Location:685
      RRM_CIRBP_RBM3; RNA recognition motif (RRM) found in cold inducible RNA binding protein (CIRBP), RNA binding motif protein 3 (RBM3) and similar proteins
    5. NM_001379425.1NP_001366354.1  cold-inducible RNA-binding protein isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC159999
      Conserved Domains (1) summary
      cd12449
      Location:685
      RRM_CIRBP_RBM3; RNA recognition motif (RRM) found in cold inducible RNA binding protein (CIRBP), RNA binding motif protein 3 (RBM3) and similar proteins
    6. NM_007705.3NP_031731.1  cold-inducible RNA-binding protein isoform 1

      See identical proteins and their annotated locations for NP_031731.1

      Status: VALIDATED

      Source sequence(s)
      AI841072, AK132584
      Consensus CDS
      CCDS35975.1
      UniProtKB/Swiss-Prot
      P60824
      Related
      ENSMUSP00000101004.3, ENSMUST00000105365.9
      Conserved Domains (1) summary
      cd12449
      Location:685
      RRM_CIRBP_RBM3; RNA recognition motif (RRM) found in cold inducible RNA binding protein (CIRBP), RNA binding motif protein 3 (RBM3) and similar proteins

    RNA

    1. NR_152857.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC159999, BC075699, BE985260, BQ445205, CJ046415
      Related
      ENSMUST00000054666.7

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      80001824..80008620
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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