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    Cfl2 cofilin 2, muscle [ Mus musculus (house mouse) ]

    Gene ID: 12632, updated on 5-Sep-2021

    Summary

    Official Symbol
    Cfl2provided by MGI
    Official Full Name
    cofilin 2, muscleprovided by MGI
    Primary source
    MGI:MGI:101763
    See related
    Ensembl:ENSMUSG00000062929
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Expression
    Broad expression in heart adult (RPKM 32.0), bladder adult (RPKM 27.8) and 24 other tissues See more
    Orthologs
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    Genomic context

    See Cfl2 in Genome Data Viewer
    Location:
    12; 12 C1
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (54905602..54910065, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (54858815..54862877, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 12 NC_000078.5 (55959804..55963864, complement)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 22317 Neighboring gene sorting nexin 6 Neighboring gene bromodomain adjacent to zinc finger domain 1A Neighboring gene predicted gene, 51983 Neighboring gene predicted gene, 24296

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables actin filament binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables actin filament binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in I band ISO
    Inferred from Sequence Orthology
    more info
     
    located_in Z disc ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in actin cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_007688.2NP_031714.1  cofilin-2

      See identical proteins and their annotated locations for NP_031714.1

      Status: VALIDATED

      Source sequence(s)
      AC154732
      Consensus CDS
      CCDS36448.1
      UniProtKB/Swiss-Prot
      P45591
      UniProtKB/TrEMBL
      Q3UHW9
      Related
      ENSMUSP00000077262.8, ENSMUST00000078124.8
      Conserved Domains (1) summary
      cd11286
      Location:3153
      ADF_cofilin_like; Cofilin, Destrin, and related actin depolymerizing factors

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      54905602..54910065 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006515452.4XP_006515515.1  cofilin-2 isoform X1

      See identical proteins and their annotated locations for XP_006515515.1

      Conserved Domains (1) summary
      cd11286
      Location:10136
      ADF_cofilin_like; Cofilin, Destrin, and related actin depolymerizing factors
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