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    Cebpg CCAAT/enhancer binding protein (C/EBP), gamma [ Mus musculus (house mouse) ]

    Gene ID: 12611, updated on 31-Jan-2019

    Summary

    Official Symbol
    Cebpgprovided by MGI
    Official Full Name
    CCAAT/enhancer binding protein (C/EBP), gammaprovided by MGI
    Primary source
    MGI:MGI:104982
    See related
    Ensembl:ENSMUSG00000056216
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gpe1bp; Ig/EBP; GPE1-BP; C/EBP[g]; C/EBPgamma
    Expression
    Ubiquitous expression in liver E18 (RPKM 10.2), CNS E11.5 (RPKM 8.7) and 28 other tissues See more
    Orthologs

    Genomic context

    See Cebpg in Genome Data Viewer
    Location:
    7; 7 B2
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 7 NC_000073.6 (35046422..35056566, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (35831441..35841585, complement)

    Chromosome 7 - NC_000073.6Genomic Context describing neighboring genes Neighboring gene peptidase D Neighboring gene predicted gene, 35534 Neighboring gene predicted gene, 35484 Neighboring gene predicted gene, 35611 Neighboring gene CCAAT/enhancer binding protein (C/EBP), alpha

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    • Tuberculosis, organism-specific biosystem (from KEGG)
      Tuberculosis, organism-specific biosystemTuberculosis, or TB, is an infectious disease caused by Mycobacterium tuberculosis. One third of the world's population is thought to be infected with TB. About 90% of those infected result in latent...
    • Tuberculosis, conserved biosystem (from KEGG)
      Tuberculosis, conserved biosystemTuberculosis, or TB, is an infectious disease caused by Mycobacterium tuberculosis. One third of the world's population is thought to be infected with TB. About 90% of those infected result in latent...

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    DNA-binding transcription activator activity, RNA polymerase II-specific ISO
    Inferred from Sequence Orthology
    more info
     
    NOT DNA-binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    RNA polymerase II proximal promoter sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    RNA polymerase II proximal promoter sequence-specific DNA binding, bending ISO
    Inferred from Sequence Orthology
    more info
     
    double-stranded DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein heterodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    protein homodimerization activity NAS
    Non-traceable Author Statement
    more info
    PubMed 
    sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    transcription factor binding ISO
    Inferred from Sequence Orthology
    more info
     
    transcription factor binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Process Evidence Code Pubs
    B cell differentiation IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    chromatin remodeling TAS
    Traceable Author Statement
    more info
    PubMed 
    enucleate erythrocyte differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    immune response IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mRNA metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    natural killer cell mediated cytotoxicity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of DNA-binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleosome disassembly TAS
    Traceable Author Statement
    more info
    PubMed 
    positive regulation of DNA repair ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    positive regulation of interferon-gamma biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    NOT regulation of transcription, DNA-templated IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    CCAAT/enhancer-binding protein gamma
    Names
    G-CSF promoter element 1 binding protein
    GPE1-BP (C/EBP gamma)
    GPE1-binding protein
    IG/EBP-1
    c/EBP gamma
    granulocyte colony-stimulating factor promoter element 1-binding protein
    immunoglobulin enhancer-binding protein 1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009884.3NP_034014.1  CCAAT/enhancer-binding protein gamma

      See identical proteins and their annotated locations for NP_034014.1

      Status: VALIDATED

      Source sequence(s)
      AC149058, AK159544, BE987706, CJ092456
      Consensus CDS
      CCDS21144.1
      UniProtKB/Swiss-Prot
      P53568
      UniProtKB/TrEMBL
      Q54AJ1
      Related
      ENSMUSP00000118588.1, ENSMUST00000130491.2
      Conserved Domains (1) summary
      cd14713
      Location:60120
      bZIP_CEBPG; Basic leucine zipper (bZIP) domain of CCAAT/enhancer-binding protein gamma (CEBPG): a DNA-binding and dimerization domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000073.6 Reference GRCm38.p4 C57BL/6J

      Range
      35046422..35056566 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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