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    Cebpg CCAAT/enhancer binding protein (C/EBP), gamma [ Mus musculus (house mouse) ]

    Gene ID: 12611, updated on 23-Jun-2021

    Summary

    Official Symbol
    Cebpgprovided by MGI
    Official Full Name
    CCAAT/enhancer binding protein (C/EBP), gammaprovided by MGI
    Primary source
    MGI:MGI:104982
    See related
    Ensembl:ENSMUSG00000056216
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gpe1; Ig/E; GPE1-; Gpe1bp; Ig/EBP; C/EBPga; GPE1-BP; C/EBP[g]; C/EBPgamma
    Expression
    Ubiquitous expression in liver E18 (RPKM 10.2), CNS E11.5 (RPKM 8.7) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Cebpg in Genome Data Viewer
    Location:
    7; 7 B2
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (34745847..34755991, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (35046422..35056566, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (35831441..35841585, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene peptidase D Neighboring gene predicted gene, 25922 Neighboring gene predicted gene, 35534 Neighboring gene predicted gene 45095 Neighboring gene predicted gene, 35611 Neighboring gene CCAAT/enhancer binding protein (C/EBP), alpha

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables DNA-binding transcription activator activity, RNA polymerase II-specific ISO
    Inferred from Sequence Orthology
    more info
     
    NOT enables DNA-binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding, bending ISO
    Inferred from Sequence Orthology
    more info
     
    enables double-stranded DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein-containing complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables sequence-specific double-stranded DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables transcription factor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables transcription factor binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within B cell differentiation IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in chromatin remodeling TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in enucleate erythrocyte differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in immune response IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within mRNA metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in natural killer cell mediated cytotoxicity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of DNA-binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in nucleosome disassembly TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in positive regulation of DNA repair ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    involved_in positive regulation of interferon-gamma production IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    NOT acts_upstream_of_or_within regulation of transcription, DNA-templated IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    CCAAT/enhancer-binding protein gamma
    Names
    G-CSF promoter element 1 binding protein
    GPE1-BP (C/EBP gamma)
    GPE1-binding protein
    IG/EBP-1
    c/EBP gamma
    granulocyte colony-stimulating factor promoter element 1-binding protein
    immunoglobulin enhancer-binding protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009884.3NP_034014.1  CCAAT/enhancer-binding protein gamma

      See identical proteins and their annotated locations for NP_034014.1

      Status: VALIDATED

      Source sequence(s)
      AC149058, AK159544, BE987706, CJ092456
      Consensus CDS
      CCDS21144.1
      UniProtKB/Swiss-Prot
      P53568
      UniProtKB/TrEMBL
      Q54AJ1
      Related
      ENSMUSP00000118588.2, ENSMUST00000130491.3
      Conserved Domains (1) summary
      cd14713
      Location:60120
      bZIP_CEBPG; Basic leucine zipper (bZIP) domain of CCAAT/enhancer-binding protein gamma (CEBPG): a DNA-binding and dimerization domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      34745847..34755991 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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