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    Cebpz CCAAT/enhancer binding protein zeta [ Mus musculus (house mouse) ]

    Gene ID: 12607, updated on 23-Jun-2021

    Summary

    Official Symbol
    Cebpzprovided by MGI
    Official Full Name
    CCAAT/enhancer binding protein zetaprovided by MGI
    Primary source
    MGI:MGI:109386
    See related
    Ensembl:ENSMUSG00000024081
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Cbf; CBF2; Cebpa; AI848081; Cebpa-rs1
    Expression
    Broad expression in CNS E11.5 (RPKM 12.2), placenta adult (RPKM 6.5) and 23 other tissues See more
    Orthologs
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    Genomic context

    See Cebpz in Genome Data Viewer
    Location:
    17; 17 E3
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (79226432..79244499, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (78919003..78937070, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (79318343..79336410, complement)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 2-alpha kinase 2 Neighboring gene eukaryotic translation elongation factor 1 alpha 1 pseudogene Neighboring gene predicted gene, 26637 Neighboring gene sulfotransferase family, cytosolic, 6B, member 1 Neighboring gene CCAAT/enhancer binding protein (C/EBP), zeta, opposite strand Neighboring gene NADH:ubiquinone oxidoreductase complex assembly factor 7 Neighboring gene protein kinase D3 Neighboring gene predicted gene, 41622

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 
    • Chemically induced (ENU) (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC36087

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables transcription coactivator activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of CCAAT-binding factor complex ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    CCAAT/enhancer-binding protein zeta
    Names
    CCAAT-binding factor
    CCAAT-box-binding transcription factor
    CCAAT/enhancer binding protein alpha (C/EBP) related sequence 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024806.2NP_001019977.1  CCAAT/enhancer-binding protein zeta

      See identical proteins and their annotated locations for NP_001019977.1

      Status: VALIDATED

      Source sequence(s)
      AI848081, AK017537, AK158771, BY077658
      Consensus CDS
      CCDS28981.1
      UniProtKB/Swiss-Prot
      P53569
      UniProtKB/TrEMBL
      A0A0R4J046
      Related
      ENSMUSP00000024885.9, ENSMUST00000024885.10
      Conserved Domains (3) summary
      COG5593
      Location:179987
      COG5593; Nucleic-acid-binding protein possibly involved in ribosomal biogenesis [Translation, ribosomal structure and biogenesis]
      pfam03914
      Location:523732
      CBF; CBF/Mak21 family
      cl17018
      Location:273436
      FANC; Fanconi anemia ID complex proteins FANCI and FANCD2

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      79226432..79244499 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006523558.5XP_006523621.1  CCAAT/enhancer-binding protein zeta isoform X1

      Conserved Domains (2) summary
      pfam03914
      Location:1181
      CBF; CBF/Mak21 family
      pfam04147
      Location:275435
      Nop14; Nop14-like family

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_009882.2: Suppressed sequence

      Description
      NM_009882.2: This RefSeq was permanently suppressed because it is a nonsense-mediated decay (NMD) candidate.
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