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    OR1M1 olfactory receptor family 1 subfamily M member 1 [ Homo sapiens (human) ]

    Gene ID: 125963, updated on 17-Jun-2024

    Summary

    Official Symbol
    OR1M1provided by HGNC
    Official Full Name
    olfactory receptor family 1 subfamily M member 1provided by HGNC
    Primary source
    HGNC:HGNC:8220
    See related
    Ensembl:ENSG00000170929 AllianceGenome:HGNC:8220
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    OR19-5; OR19-6
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
    Orthologs
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    Genomic context

    See OR1M1 in Genome Data Viewer
    Location:
    19p13.2
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (9087061..9095669)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (9213236..9221832)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (9197737..9206345)

    Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene mucin 16, cell surface associated Neighboring gene MED14-independent group 3 enhancer GRCh37_chr19:9150106-9151305 Neighboring gene tRNA-Gln (anticodon TTG) 8-1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:9160639-9161138 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr19:9165241-9165920 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr19:9180050-9180984 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr19:9180985-9181918 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr19:9184777-9185664 Neighboring gene olfactory receptor family 1 subfamily M member 4 pseudogene Neighboring gene olfactory receptor family 7 subfamily G member 2 Neighboring gene olfactory receptor family 7 subfamily G member 1

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in detection of chemical stimulus involved in sensory perception of smell IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    olfactory receptor 1M1
    Names
    olfactory receptor 19-6
    olfactory receptor OR19-5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001004456.2NP_001004456.1  olfactory receptor 1M1

      See identical proteins and their annotated locations for NP_001004456.1

      Status: VALIDATED

      Source sequence(s)
      AC011464
      Consensus CDS
      CCDS32896.1
      UniProtKB/Swiss-Prot
      B9EHA6, Q6IFJ3, Q8NGA1, Q96R91
      UniProtKB/TrEMBL
      A0A126GVI5
      Related
      ENSP00000493107.1, ENST00000641627.1
      Conserved Domains (1) summary
      cd15918
      Location:25294
      7tmA_OR1_7-like; olfactory receptor families 1, 7, and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

      Range
      9087061..9095669
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060943.1 Alternate T2T-CHM13v2.0

      Range
      9213236..9221832
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)