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    Cdyl chromodomain protein, Y chromosome-like [ Mus musculus (house mouse) ]

    Gene ID: 12593, updated on 31-Jan-2019

    Summary

    Official Symbol
    Cdylprovided by MGI
    Official Full Name
    chromodomain protein, Y chromosome-likeprovided by MGI
    Primary source
    MGI:MGI:1339956
    See related
    Ensembl:ENSMUSG00000059288
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AI325931
    Expression
    Biased expression in testis adult (RPKM 40.9), limb E14.5 (RPKM 5.9) and 13 other tissues See more
    Orthologs

    Genomic context

    See Cdyl in Genome Data Viewer
    Location:
    13 A3.3; 13 14.39 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 13 NC_000079.6 (35659810..35874064)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (35751731..35965933)

    Chromosome 13 - NC_000079.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1700011B04 gene Neighboring gene RIKEN cDNA 1700019C18 gene Neighboring gene ribonuclease P 40 subunit Neighboring gene protein phosphatase 1, regulatory subunit 3G Neighboring gene predicted gene, 30127

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (1)  1 citation
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    catalytic activity IEA
    Inferred from Electronic Annotation
    more info
     
    chromatin binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    crotonyl-CoA hydratase activity ISO
    Inferred from Sequence Orthology
    more info
     
    histone acetyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    lyase activity IEA
    Inferred from Electronic Annotation
    more info
     
    NOT methylated histone binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding, bridging ISO
    Inferred from Sequence Orthology
    more info
     
    transcription corepressor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    transcription corepressor activity ISO
    Inferred from Sequence Orthology
    more info
     
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    transferase activity, transferring acyl groups IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of peptidyl-lysine crotonylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    negative regulation of peptidyl-lysine crotonylation ISO
    Inferred from Sequence Orthology
    more info
     
    random inactivation of X chromosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    spermatid development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    spermatogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    chromosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nuclear speck ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    chromodomain Y-like protein
    Names
    CDY-like
    crotonyl-CoA hydratase
    putative histone acetyltransferase Cdyl
    NP_001116858.1
    NP_034011.1
    XP_006516599.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001123386.1NP_001116858.1  chromodomain Y-like protein isoform 2

      See identical proteins and their annotated locations for NP_001116858.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks several 5' exons but has an alternate 5' exon, as compared to variant 1. The resulting isoform (2) has a different and shorter N-terminus, as compared to isoform 1.
      Source sequence(s)
      AK028162, BC062123, BG229669
      Consensus CDS
      CCDS49236.1
      UniProtKB/Swiss-Prot
      Q9WTK2
      Related
      ENSMUSP00000131784.2, ENSMUST00000163595.2
      Conserved Domains (2) summary
      cd06558
      Location:290486
      crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...
      smart00298
      Location:760
      CHROMO; Chromatin organization modifier domain
    2. NM_009881.3NP_034011.1  chromodomain Y-like protein isoform 1

      See identical proteins and their annotated locations for NP_034011.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (1).
      Source sequence(s)
      AK028162, BC055103, BG229669, BY090531
      Consensus CDS
      CCDS49235.1
      UniProtKB/Swiss-Prot
      Q9WTK2
      Related
      ENSMUSP00000074707.6, ENSMUST00000075220.13
      Conserved Domains (2) summary
      cd06558
      Location:339535
      crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...
      smart00298
      Location:55109
      CHROMO; Chromatin organization modifier domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000079.6 Reference GRCm38.p4 C57BL/6J

      Range
      35659810..35874064
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006516536.2XP_006516599.1  chromodomain Y-like protein isoform X1

      Conserved Domains (2) summary
      cd06558
      Location:315511
      crotonase-like; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. ...
      smart00298
      Location:3185
      CHROMO; Chromatin organization modifier domain

    RNA

    1. XR_382045.3 RNA Sequence

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