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    Cct8 chaperonin containing Tcp1, subunit 8 (theta) [ Mus musculus (house mouse) ]

    Gene ID: 12469, updated on 31-Jan-2019

    Summary

    Official Symbol
    Cct8provided by MGI
    Official Full Name
    chaperonin containing Tcp1, subunit 8 (theta)provided by MGI
    Primary source
    MGI:MGI:107183
    See related
    Ensembl:ENSMUSG00000025613
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Cctq; Tcpq; AI132397
    Expression
    Broad expression in CNS E11.5 (RPKM 95.8), placenta adult (RPKM 88.4) and 25 other tissues See more
    Orthologs

    Genomic context

    See Cct8 in Genome Data Viewer
    Location:
    16; 16 C3.3
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 16 NC_000082.6 (87483325..87495869, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 16 NC_000082.5 (87483570..87496114, complement)

    Chromosome 16 - NC_000082.6Genomic Context describing neighboring genes Neighboring gene listerin E3 ubiquitin protein ligase 1 Neighboring gene RWD domain containing 2B Neighboring gene ubiquitin specific peptidase 16 Neighboring gene RIKEN cDNA B130034C11 gene Neighboring gene ribosomal protein L31, pseudogene 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    unfolded protein binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    binding of sperm to zona pellucida IDA
    Inferred from Direct Assay
    more info
    PubMed 
    pore complex assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of establishment of protein localization to telomere ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of telomere maintenance via telomerase ISO
    Inferred from Sequence Orthology
    more info
     
    protein folding IEA
    Inferred from Electronic Annotation
    more info
     
    protein stabilization ISO
    Inferred from Sequence Orthology
    more info
     
    toxin transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    cell body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    chaperonin-containing T-complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    chaperonin-containing T-complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    chaperonin-containing T-complex ISO
    Inferred from Sequence Orthology
    more info
     
    cilium IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    intermediate filament cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
     
    microtubule ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    zona pellucida receptor complex IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    T-complex protein 1 subunit theta
    Names
    CCT-theta
    TCP-1-theta
    chaperonin subunit 8 (theta)

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009840.3NP_033970.3  T-complex protein 1 subunit theta

      See identical proteins and their annotated locations for NP_033970.3

      Status: VALIDATED

      Source sequence(s)
      AK075711, AK075880, AK147038, AV335786
      Consensus CDS
      CCDS37384.1
      UniProtKB/Swiss-Prot
      P42932
      UniProtKB/TrEMBL
      Q3UL22, Q8BVY8
      Related
      ENSMUSP00000026704.7, ENSMUST00000026704.13
      Conserved Domains (2) summary
      TIGR02346
      Location:10539
      chap_CCT_theta; T-complex protein 1, theta subunit
      pfam00118
      Location:39528
      Cpn60_TCP1; TCP-1/cpn60 chaperonin family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000082.6 Reference GRCm38.p4 C57BL/6J

      Range
      87483325..87495869 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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