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    Cct7 chaperonin containing Tcp1, subunit 7 (eta) [ Mus musculus (house mouse) ]

    Gene ID: 12468, updated on 31-Jan-2019

    Summary

    Official Symbol
    Cct7provided by MGI
    Official Full Name
    chaperonin containing Tcp1, subunit 7 (eta)provided by MGI
    Primary source
    MGI:MGI:107184
    See related
    Ensembl:ENSMUSG00000030007
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ccth; Cctz; AA408524; AL022769
    Expression
    Ubiquitous expression in testis adult (RPKM 177.0), CNS E11.5 (RPKM 113.9) and 28 other tissues See more
    Orthologs

    Genomic context

    See Cct7 in Genome Data Viewer
    Location:
    6; 6 C3
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 6 NC_000072.6 (85451505..85468477)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (85401499..85418471)

    Chromosome 6 - NC_000072.6Genomic Context describing neighboring genes Neighboring gene notochord homeobox Neighboring gene SET and MYND domain containing 5 Neighboring gene protease-associated domain containing 1 Neighboring gene F-box protein 41 Neighboring gene early growth response 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    identical protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    unfolded protein binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    binding of sperm to zona pellucida IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of establishment of protein localization to telomere ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of telomere maintenance via telomerase ISO
    Inferred from Sequence Orthology
    more info
     
    protein folding IEA
    Inferred from Electronic Annotation
    more info
     
    protein stabilization ISO
    Inferred from Sequence Orthology
    more info
     
    toxin transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    cell body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    chaperonin-containing T-complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    chaperonin-containing T-complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    chaperonin-containing T-complex ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    microtubule ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrion HDA PubMed 
    zona pellucida receptor complex IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    T-complex protein 1 subunit eta
    Names
    CCT-eta
    TCP-1-eta
    chaperonin containing t-complex subunit eta
    chaperonin subunit 7 (eta)

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_007638.4NP_031664.3  T-complex protein 1 subunit eta

      See identical proteins and their annotated locations for NP_031664.3

      Status: VALIDATED

      Source sequence(s)
      AC155728, AK146902, AK150160, BQ951185
      Consensus CDS
      CCDS20295.1
      UniProtKB/Swiss-Prot
      P80313
      UniProtKB/TrEMBL
      Q3TIJ7, Q3UDB1, Q3UIJ0
      Related
      ENSMUSP00000032078.6, ENSMUST00000032078.8
      Conserved Domains (2) summary
      cd03340
      Location:5525
      TCP1_eta; TCP-1 (CTT or eukaryotic type II) chaperonin family, eta subunit. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings. In contrast to bacterial group I chaperonins (GroEL), ...
      TIGR02345
      Location:3525
      chap_CCT_eta; T-complex protein 1, eta subunit

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000072.6 Reference GRCm38.p4 C57BL/6J

      Range
      85451505..85468477
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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