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    Cct4 chaperonin containing Tcp1, subunit 4 (delta) [ Mus musculus (house mouse) ]

    Gene ID: 12464, updated on 31-Jan-2019

    Summary

    Official Symbol
    Cct4provided by MGI
    Official Full Name
    chaperonin containing Tcp1, subunit 4 (delta)provided by MGI
    Primary source
    MGI:MGI:104689
    See related
    Ensembl:ENSMUSG00000007739
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    A45; Cctd; C78323; 2610204B21Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 82.4), placenta adult (RPKM 69.7) and 28 other tissues See more
    Orthologs

    Genomic context

    See Cct4 in Genome Data Viewer
    Location:
    11 A3.2; 11 14.25 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 11 NC_000077.6 (22990593..23003336)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (22890593..22903336)

    Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108167890 Neighboring gene COMM domain containing 1 Neighboring gene zinc finger (CCCH type), RNA binding motif and serine/arginine rich 1 Neighboring gene family with sequence similarity 161, member A Neighboring gene predicted gene 12059

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    unfolded protein binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    binding of sperm to zona pellucida IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of establishment of protein localization to telomere ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of telomerase RNA localization to Cajal body ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of telomerase activity ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of telomere maintenance via telomerase ISO
    Inferred from Sequence Orthology
    more info
     
    protein folding IEA
    Inferred from Electronic Annotation
    more info
     
    protein stabilization ISO
    Inferred from Sequence Orthology
    more info
     
    scaRNA localization to Cajal body ISO
    Inferred from Sequence Orthology
    more info
     
    toxin transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    cell body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    chaperonin-containing T-complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    chaperonin-containing T-complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    chaperonin-containing T-complex ISO
    Inferred from Sequence Orthology
    more info
     
    cilium IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    microtubule ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    zona pellucida receptor complex IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    T-complex protein 1 subunit delta
    Names
    CCT-delta
    T complex protein 1, delta
    TCP-1-delta
    chaperonin subunit 4 (delta)

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009837.1NP_033967.1  T-complex protein 1 subunit delta

      See identical proteins and their annotated locations for NP_033967.1

      Status: VALIDATED

      Source sequence(s)
      Z31554
      Consensus CDS
      CCDS24474.1
      UniProtKB/Swiss-Prot
      P80315
      UniProtKB/TrEMBL
      Q564F4
      Related
      ENSMUSP00000133523.1, ENSMUST00000173867.7
      Conserved Domains (2) summary
      cd03338
      Location:25538
      TCP1_delta; TCP-1 (CTT or eukaryotic type II) chaperonin family, delta subunit. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings. In contrast to bacterial group I chaperonins ...
      pfam00118
      Location:44539
      Cpn60_TCP1; TCP-1/cpn60 chaperonin family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000077.6 Reference GRCm38.p4 C57BL/6J

      Range
      22990593..23003336
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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