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    Ccnb2 cyclin B2 [ Mus musculus (house mouse) ]

    Gene ID: 12442, updated on 31-Jan-2019

    Summary

    Official Symbol
    Ccnb2provided by MGI
    Official Full Name
    cyclin B2provided by MGI
    Primary source
    MGI:MGI:88311
    See related
    Ensembl:ENSMUSG00000032218
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    CycB2
    Expression
    Broad expression in liver E14.5 (RPKM 72.5), liver E14 (RPKM 70.4) and 15 other tissues See more
    Orthologs

    Genomic context

    See Ccnb2 in Genome Data Viewer
    Location:
    9; 9 D
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 9 NC_000075.6 (70407689..70421554, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (70255496..70269361, complement)

    Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene myosin IE Neighboring gene predicted gene, 18017 Neighboring gene microRNA 5626 Neighboring gene ring finger 111 Neighboring gene SAFB-like, transcription modulator

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    cyclin-dependent protein serine/threonine kinase regulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    contributes_to protein kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein kinase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    T cell homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    cell division IEA
    Inferred from Electronic Annotation
    more info
     
    in utero embryonic development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    mitotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    positive regulation of cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    positive regulation of cell proliferation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of cyclin-dependent protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of growth IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of mitotic nuclear division IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    thymus development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    cyclin-dependent protein kinase holoenzyme complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    microtubule cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    G2/mitotic-specific cyclin-B2

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_007630.2NP_031656.2  G2/mitotic-specific cyclin-B2

      See identical proteins and their annotated locations for NP_031656.2

      Status: VALIDATED

      Source sequence(s)
      AA033463, AK076122, BY300844
      Consensus CDS
      CCDS23320.1
      UniProtKB/Swiss-Prot
      P30276
      Related
      ENSMUSP00000034742.6, ENSMUST00000034742.7
      Conserved Domains (2) summary
      pfam00134
      Location:137262
      Cyclin_N; Cyclin, N-terminal domain
      pfam02984
      Location:264382
      Cyclin_C; Cyclin, C-terminal domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000075.6 Reference GRCm38.p4 C57BL/6J

      Range
      70407689..70421554 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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