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    Capza2 capping protein (actin filament) muscle Z-line, alpha 2 [ Mus musculus (house mouse) ]

    Gene ID: 12343, updated on 31-Jan-2019

    Summary

    Official Symbol
    Capza2provided by MGI
    Official Full Name
    capping protein (actin filament) muscle Z-line, alpha 2provided by MGI
    Primary source
    MGI:MGI:106222
    See related
    Ensembl:ENSMUSG00000015733
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Cappa2; AW208808; 1110053K06Rik
    Expression
    Broad expression in bladder adult (RPKM 63.7), frontal lobe adult (RPKM 46.4) and 23 other tissues See more
    Orthologs

    Genomic context

    See Capza2 in Genome Data Viewer
    Location:
    6 A2; 6 7.96 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 6 NC_000072.6 (17637098..17666534)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (17587098..17616534)

    Chromosome 6 - NC_000072.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 46953 Neighboring gene met proto-oncogene Neighboring gene four and a half LIM domains 3 pseudogene Neighboring gene metal response element binding transcription factor 2 pseudogene Neighboring gene suppression of tumorigenicity 7

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    actin binding IEA
    Inferred from Electronic Annotation
    more info
     
    actin filament binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    actin cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    actin filament capping IEA
    Inferred from Electronic Annotation
    more info
     
    barbed-end actin filament capping IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    F-actin capping protein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    F-actin capping protein complex IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    actin cortical patch IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    brush border IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cortical cytoskeleton IDA
    Inferred from Direct Assay
    more info
    PubMed 
    membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    F-actin-capping protein subunit alpha-2
    Names
    capZ alpha-2
    capping protein alpha 2

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_007604.3NP_031630.1  F-actin-capping protein subunit alpha-2

      See identical proteins and their annotated locations for NP_031630.1

      Status: VALIDATED

      Source sequence(s)
      BC082589, BM204346, BY232398, CX734558
      Consensus CDS
      CCDS19926.1
      UniProtKB/Swiss-Prot
      P47754
      UniProtKB/TrEMBL
      Q5DQJ3
      Related
      ENSMUSP00000015877.7, ENSMUST00000015877.13
      Conserved Domains (1) summary
      pfam01267
      Location:17283
      F-actin_cap_A; F-actin capping protein alpha subunit

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000072.6 Reference GRCm38.p4 C57BL/6J

      Range
      17637098..17666534
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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