Format

Send to:

Choose Destination
    • Showing Current items.

    Capns1 calpain, small subunit 1 [ Mus musculus (house mouse) ]

    Gene ID: 12336, updated on 23-Jun-2021

    Summary

    Official Symbol
    Capns1provided by MGI
    Official Full Name
    calpain, small subunit 1provided by MGI
    Primary source
    MGI:MGI:88266
    See related
    Ensembl:ENSMUSG00000001794
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ca; Cap; Cdps; Css1; Capa4; Capn4; Capa-4; D7Ertd146; D7Ertd146e
    Expression
    Ubiquitous expression in adrenal adult (RPKM 274.2), mammary gland adult (RPKM 214.7) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Capns1 in Genome Data Viewer
    Location:
    7 B1; 7 17.31 cM
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (29886359..29898308, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (30186934..30198883, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (30971961..30980067, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene predicted gene 5113 Neighboring gene predicted gene, 53356 Neighboring gene cytochrome c oxidase subunit 7A1 Neighboring gene tubulin folding cofactor B Neighboring gene polymerase (RNA) II (DNA directed) polypeptide I Neighboring gene ovo like zinc finger 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables calcium-dependent cysteine-type endopeptidase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane TAS
    Traceable Author Statement
    more info
     

    General protein information

    Preferred Names
    calpain small subunit 1
    Names
    CANP small subunit
    calcium-activated neutral proteinase small subunit
    calcium-dependent protease small subunit 1
    calpain 4
    calpain regulatory subunit
    NP_033925.2
    XP_006539551.1
    XP_011248722.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009795.4NP_033925.2  calpain small subunit 1

      See identical proteins and their annotated locations for NP_033925.2

      Status: VALIDATED

      Source sequence(s)
      BC090988, BU700497, BY133208, BY296628
      Consensus CDS
      CCDS21082.1
      UniProtKB/Swiss-Prot
      O88456
      UniProtKB/TrEMBL
      A0A0R4IZW8
      Related
      ENSMUSP00000117951.3, ENSMUST00000126116.3
      Conserved Domains (1) summary
      cd16188
      Location:100268
      EFh_PEF_CPNS1_2; Penta-EF hand, calcium binding motifs, found in calcium-dependent protease small subunit CAPNS1 and CAPNS2

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      29886359..29898308 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006539488.3XP_006539551.1  calpain small subunit 1 isoform X1

      See identical proteins and their annotated locations for XP_006539551.1

      UniProtKB/Swiss-Prot
      O88456
      UniProtKB/TrEMBL
      A0A0R4IZW8
      Related
      ENSMUSP00000001845.6, ENSMUST00000001845.13
      Conserved Domains (1) summary
      cd16188
      Location:100268
      EFh_PEF_CPNS1_2; Penta-EF hand, calcium binding motifs, found in calcium-dependent protease small subunit CAPNS1 and CAPNS2
    2. XM_011250420.1XP_011248722.1  calpain small subunit 1 isoform X2

      Conserved Domains (1) summary
      cd16188
      Location:1156
      EFh_PEF_CPNS1_2; Penta-EF hand, calcium binding motifs, found in calcium-dependent protease small subunit CAPNS1 and CAPNS2
    Support Center