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    Calm3 calmodulin 3 [ Mus musculus (house mouse) ]

    Gene ID: 12315, updated on 23-Jun-2021

    Summary

    Official Symbol
    Calm3provided by MGI
    Official Full Name
    calmodulin 3provided by MGI
    Primary source
    MGI:MGI:103249
    See related
    Ensembl:ENSMUSG00000019370
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    CaMA; Cam3; Camc; R75142
    Expression
    Ubiquitous expression in cortex adult (RPKM 496.4), frontal lobe adult (RPKM 463.0) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Calm3 in Genome Data Viewer
    Location:
    7 A2; 7 9.15 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (16649304..16657957, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (16915379..16924032, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (17500728..17509381, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene guanine nucleotide binding protein (G protein), gamma 8 Neighboring gene prostaglandin I receptor (IP) Neighboring gene predicted gene, 45972 Neighboring gene predicted gene, 32630 Neighboring gene PNMA family member 8B

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables N-terminal myristoylation domain binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables adenylate cyclase activator activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables adenylate cyclase binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables calcium channel inhibitor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables calcium ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables calcium ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables calcium ion binding TAS
    Traceable Author Statement
    more info
    PubMed 
    enables calcium-dependent protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables disordered domain specific binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables enzyme regulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables nitric-oxide synthase binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables nitric-oxide synthase regulator activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables phosphatidylinositol 3-kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein N-terminus binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein domain specific binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein phosphatase activator activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables titin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables transmembrane transporter binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables type 3 metabotropic glutamate receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within G2/M transition of mitotic cell cycle IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in activation of adenylate cyclase activity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in calcium-mediated signaling ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in detection of calcium ion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in establishment of protein localization to membrane ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in establishment of protein localization to mitochondrial membrane ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of ryanodine-sensitive calcium-release channel activity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of cyclic-nucleotide phosphodiesterase activity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of nitric-oxide synthase activity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of phosphoprotein phosphatase activity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of protein dephosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of ryanodine-sensitive calcium-release channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in positive regulation of ryanodine-sensitive calcium-release channel activity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of cardiac muscle contraction ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of cytokinesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of heart rate ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of high voltage-gated calcium channel activity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of ryanodine-sensitive calcium-release channel activity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of synaptic vesicle endocytosis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of synaptic vesicle exocytosis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in response to calcium ion ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of calcium channel complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of catalytic complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in growth cone ISO
    Inferred from Sequence Orthology
    more info
     
    colocalizes_with mitochondrial membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in myelin sheath IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in myelin sheath ISO
    Inferred from Sequence Orthology
    more info
     
    located_in neuron projection ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in sarcomere ISO
    Inferred from Sequence Orthology
    more info
     
    located_in spindle microtubule ISO
    Inferred from Sequence Orthology
    more info
     
    located_in spindle pole ISO
    Inferred from Sequence Orthology
    more info
     
    colocalizes_with synaptic vesicle membrane ISO
    Inferred from Sequence Orthology
    more info
     
    part_of voltage-gated potassium channel complex IGI
    Inferred from Genetic Interaction
    more info
    PubMed 

    General protein information

    Preferred Names
    calmodulin-3
    Names
    caM
    NP_031616.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_007590.3NP_031616.1  calmodulin-3

      See identical proteins and their annotated locations for NP_031616.1

      Status: VALIDATED

      Source sequence(s)
      BC050926, BE853985
      Consensus CDS
      CCDS39789.1
      UniProtKB/Swiss-Prot
      P0DP26, P0DP27, P0DP28
      Related
      ENSMUSP00000019514.10, ENSMUST00000019514.10
      Conserved Domains (1) summary
      PTZ00184
      Location:1149
      PTZ00184; calmodulin; Provisional

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      16649304..16657957 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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