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    Cab39 calcium binding protein 39 [ Mus musculus (house mouse) ]

    Gene ID: 12283, updated on 26-Sep-2022

    Summary

    Official Symbol
    Cab39provided by MGI
    Official Full Name
    calcium binding protein 39provided by MGI
    Primary source
    MGI:MGI:107438
    See related
    Ensembl:ENSMUSG00000036707 AllianceGenome:MGI:107438
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    MO25; MO25alpha
    Summary
    Predicted to enable calcium ion binding activity; kinase binding activity; and protein serine/threonine kinase activator activity. Acts upstream of or within activation of protein kinase activity. Predicted to be located in cytosol and membrane. Predicted to be part of protein-containing complex. Predicted to colocalize with Z disc. Is expressed in several structures, including clavicle; cranial ganglion; dorsal root ganglion; neural retina; and secondary oocyte. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Orthologous to human CAB39 (calcium binding protein 39). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in bladder adult (RPKM 37.9), colon adult (RPKM 29.2) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Cab39 in Genome Data Viewer
    Location:
    1; 1 C5
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (85721148..85779298)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (85793441..85851577)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene microRNA 8096 Neighboring gene RIKEN cDNA 9930111H07 gene Neighboring gene integral membrane protein 2C Neighboring gene predicted gene, 32302 Neighboring gene predicted gene, 51745

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables calcium ion binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    enables kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein kinase activator activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein serine/threonine kinase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables protein serine/threonine kinase activator activity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    colocalizes_with Z disc ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IC
    Inferred by Curator
    more info
    PubMed 
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
     
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of serine/threonine protein kinase complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    calcium-binding protein 39
    Names
    calcium binding protein, 39 kDa

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001355046.1NP_001341975.1  calcium-binding protein 39

      Status: VALIDATED

      Source sequence(s)
      AC107707, AC161342
      Consensus CDS
      CCDS15112.1
      UniProtKB/Swiss-Prot
      Q8VDZ8
      UniProtKB/TrEMBL
      A0A6P5PRA7, A0A8C6MPY0
      Conserved Domains (1) summary
      pfam08569
      Location:5334
      Mo25; Mo25-like
    2. NM_001355047.1NP_001341976.1  calcium-binding protein 39

      Status: VALIDATED

      Source sequence(s)
      AC107707, AC161342
      Consensus CDS
      CCDS15112.1
      UniProtKB/Swiss-Prot
      Q8VDZ8
      UniProtKB/TrEMBL
      A0A6P5PRA7, A0A8C6MPY0
      Conserved Domains (1) summary
      pfam08569
      Location:5334
      Mo25; Mo25-like
    3. NM_133781.5NP_598542.3  calcium-binding protein 39

      See identical proteins and their annotated locations for NP_598542.3

      Status: VALIDATED

      Source sequence(s)
      AA989839, AC107707, AC161342, AI604828, AK005226, BG065985, BU053240, BX525012, CB524885
      Consensus CDS
      CCDS15112.1
      UniProtKB/Swiss-Prot
      Q06138, Q8VDZ8
      UniProtKB/TrEMBL
      A0A6P5PRA7, A0A8C6MPY0
      Related
      ENSMUSP00000108987.2, ENSMUST00000113360.8
      Conserved Domains (1) summary
      pfam08569
      Location:5334
      Mo25; Mo25-like

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      85721148..85779298
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036155674.1XP_036011567.1  calcium-binding protein 39 isoform X1

      UniProtKB/Swiss-Prot
      Q8VDZ8
      UniProtKB/TrEMBL
      A0A6P5PRA7, A0A8C6MPY0
      Conserved Domains (1) summary
      pfam08569
      Location:5334
      Mo25; Mo25-like
    2. XM_036155658.1XP_036011551.1  calcium-binding protein 39 isoform X1

      UniProtKB/Swiss-Prot
      Q8VDZ8
      UniProtKB/TrEMBL
      A0A6P5PRA7, A0A8C6MPY0
      Conserved Domains (1) summary
      pfam08569
      Location:5334
      Mo25; Mo25-like
    3. XM_011247907.4XP_011246209.1  calcium-binding protein 39 isoform X1

      See identical proteins and their annotated locations for XP_011246209.1

      UniProtKB/Swiss-Prot
      Q06138, Q8VDZ8
      UniProtKB/TrEMBL
      A0A6P5PRA7, A0A8C6MPY0
      Conserved Domains (1) summary
      pfam08569
      Location:5334
      Mo25; Mo25-like
    4. XM_030243907.2XP_030099767.1  calcium-binding protein 39 isoform X1

      UniProtKB/Swiss-Prot
      Q8VDZ8
      UniProtKB/TrEMBL
      A0A6P5PRA7, A0A8C6MPY0
      Conserved Domains (1) summary
      pfam08569
      Location:5334
      Mo25; Mo25-like
    5. XM_006529091.4XP_006529154.1  calcium-binding protein 39 isoform X1

      See identical proteins and their annotated locations for XP_006529154.1

      UniProtKB/Swiss-Prot
      Q06138, Q8VDZ8
      UniProtKB/TrEMBL
      A0A6P5PRA7, A0A8C6MPY0
      Related
      ENSMUSP00000095270.3, ENSMUST00000097666.4
      Conserved Domains (1) summary
      pfam08569
      Location:5334
      Mo25; Mo25-like