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    Commd3 COMM domain containing 3 [ Mus musculus (house mouse) ]

    Gene ID: 12238, updated on 8-Feb-2024


    Official Symbol
    Commd3provided by MGI
    Official Full Name
    COMM domain containing 3provided by MGI
    Primary source
    See related
    Ensembl:ENSMUSG00000051154 AllianceGenome:MGI:88218
    Gene type
    protein coding
    RefSeq status
    Mus musculus
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Bup; D2Ertd542e
    Predicted to act upstream of or within sodium ion transport. Predicted to be located in cytoplasm and nucleus. Is expressed in alimentary system and genitourinary system. Orthologous to human COMMD3 (COMM domain containing 3). [provided by Alliance of Genome Resources, Apr 2022]
    Ubiquitous expression in adrenal adult (RPKM 46.7), CNS E14 (RPKM 37.4) and 28 other tissues See more
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    Genomic context

    See Commd3 in Genome Data Viewer
    2 A3; 2 12.9 cM
    Exon count:
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (18677246..18681042)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (18672435..18676231)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene aminoadipate-semialdehyde dehydrogenase pseudogene Neighboring gene predicted gene, 50498 Neighboring gene ATP synthase subunit f, mitochondrial pseudogene Neighboring gene STARR-seq mESC enhancer starr_03812 Neighboring gene Bmi1 polycomb ring finger oncogene Neighboring gene predicted gene, 46725

    Genomic regions, transcripts, and products


    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a



    Alleles of this type are documented at Mouse Genome Informatics  (MGI)


    Products Interactant Other Gene Complex Source Pubs Description

    General gene information


    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    acts_upstream_of_or_within monoatomic ion transport IEA
    Inferred from Electronic Annotation
    more info
    acts_upstream_of_or_within sodium ion transport IEA
    Inferred from Electronic Annotation
    more info
    involved_in sodium ion transport IEA
    Inferred from Electronic Annotation
    more info
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info

    General protein information

    Preferred Names
    COMM domain-containing protein 3
    Bmi1 upstream
    bmi-1 upstream gene protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_147778.4NP_680087.1  COMM domain-containing protein 3

      See identical proteins and their annotated locations for NP_680087.1

      Status: VALIDATED

      Source sequence(s)
      AK041634, AK145999, BE950806
      Consensus CDS
      A2ASR4, Q3UKI1, Q63829, Q8C9P5
      ENSMUSP00000049882.5, ENSMUST00000061158.5
      Conserved Domains (1) summary
      Commd3; COMM_Domain containing protein 3. The COMM Domain is found at the C-terminus of a variety of proteins; presumably all COMM_Domain containing proteins are located in the nucleus and the COMM domain plays a role in protein-protein interactions. Several ...

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J


    1. NC_000068.8 Reference GRCm39 C57BL/6J

      GenBank, FASTA, Sequence Viewer (Graphics)