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    PRR20A proline rich 20A [ Homo sapiens (human) ]

    Gene ID: 122183, updated on 10-Oct-2023

    Summary

    Official Symbol
    PRR20Aprovided by HGNC
    Official Full Name
    proline rich 20Aprovided by HGNC
    Primary source
    HGNC:HGNC:24754
    See related
    Ensembl:ENSG00000204919 AllianceGenome:HGNC:24754
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    PRR20; PRR20B; PRR20C; PRR20D; PRR20E
    Summary
    This gene is one of five identical loci in a cluster on chromosome 13q21.1. The predicted protein is proline-rich and contains several dopamine D4 receptor signatures and PRINTS domains. [provided by RefSeq, Oct 2008]
    Annotation information
    Note: This gene is one of five identical loci in a cluster on chromosome 13q21.1. Similar gene clusters are suggested in rhesus, mouse, rabbit, dog, cow, platypus, and armadillo genomic sequences. [22 Jul 2008]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

    See PRR20A in Genome Data Viewer
    Location:
    13q21.1
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 13 NC_000013.11 (57140918..57143939)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 13 NC_060937.1 (56357788..56360807)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 13 NC_000013.10 (57715052..57718073)

    Chromosome 13 - NC_000013.11Genomic Context describing neighboring genes Neighboring gene RN7SK pseudogene 6 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr13:57549287-57549788 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr13:57549789-57550288 Neighboring gene uncharacterized LOC124903235 Neighboring gene Sharpr-MPRA regulatory region 3887 Neighboring gene proline rich 20B Neighboring gene proline rich 20C

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    proline-rich protein 20A
    Names
    Proline-rich protein 20B
    Proline-rich protein 20C
    Proline-rich protein 20D
    Proline-rich protein 20E
    proline rich 20
    proline-rich protein 20

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_198441.2NP_940843.1  proline-rich protein 20A

      See identical proteins and their annotated locations for NP_940843.1

      Status: VALIDATED

      Source sequence(s)
      AL353652
      Consensus CDS
      CCDS31981.1
      UniProtKB/Swiss-Prot
      P86478, P86479, P86480, P86481, P86496, Q8N7V5
      Related
      ENSP00000367164.1, ENST00000377931.1
      Conserved Domains (1) summary
      pfam15708
      Location:1221
      PRR20; Proline-rich protein family 20

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000013.11 Reference GRCh38.p14 Primary Assembly

      Range
      57140918..57143939
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060937.1 Alternate T2T-CHM13v2.0

      Range
      56357788..56360807
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)