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    Bnip3l BCL2/adenovirus E1B interacting protein 3-like [ Mus musculus (house mouse) ]

    Gene ID: 12177, updated on 5-Feb-2019

    Summary

    Official Symbol
    Bnip3lprovided by MGI
    Official Full Name
    BCL2/adenovirus E1B interacting protein 3-likeprovided by MGI
    Primary source
    MGI:MGI:1332659
    See related
    Ensembl:ENSMUSG00000022051
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Nix; Nip3L; C86132; D14Ertd719e
    Expression
    Ubiquitous expression in liver E14 (RPKM 35.8), liver E14.5 (RPKM 29.8) and 26 other tissues See more
    Orthologs

    Genomic context

    See Bnip3l in Genome Data Viewer
    Location:
    14 D1; 14 34.6 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 14 NC_000080.6 (66985238..67008877, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (67604077..67627714, complement)

    Chromosome 14 - NC_000080.6Genomic Context describing neighboring genes Neighboring gene dihydropyrimidinase-like 2 Neighboring gene paraneoplastic antigen MA2 Neighboring gene cold shock domain containing E1, RNA binding pseudogene Neighboring gene protein phosphatase 2, regulatory subunit B, alpha Neighboring gene predicted gene, 30438

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    lamin binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein heterodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    protein homodimerization activity IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    apoptotic process IEA
    Inferred from Electronic Annotation
    more info
     
    cellular response to hypoxia ISO
    Inferred from Sequence Orthology
    more info
     
    defense response to virus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    defense response to virus ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrial outer membrane permeabilization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mitochondrial protein catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of cell death ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of mitochondrial membrane potential ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of apoptotic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of macroautophagy ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of mitochondrial membrane permeability ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of autophagy of mitochondrion IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    regulation of protein targeting to mitochondrion IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    mitochondrial envelope IEA
    Inferred from Electronic Annotation
    more info
     
    mitochondrial outer membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mitochondrial outer membrane ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrion HDA PubMed 
    mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear envelope IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nuclear envelope ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear speck ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like
    Names
    BCL2/adenovirus E1B 19 kDa-interacting protein 3-like
    BCL2/adenovirus E1B 19kDa-interacting protein 3-like
    NIP3-like protein X

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009761.3NP_033891.1  BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like

      See identical proteins and their annotated locations for NP_033891.1

      Status: VALIDATED

      Source sequence(s)
      AK004667, AK018668, BU560379
      Consensus CDS
      CCDS27227.1
      UniProtKB/Swiss-Prot
      Q9Z2F7
      Related
      ENSMUSP00000022634.8, ENSMUST00000022634.8
      Conserved Domains (1) summary
      pfam06553
      Location:22217
      BNIP3; BNIP3

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000080.6 Reference GRCm38.p4 C57BL/6J

      Range
      66985238..67008877 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017315807.1XP_017171296.1  BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like isoform X1

      Conserved Domains (1) summary
      pfam06553
      Location:17178
      BNIP3; BNIP3
    2. XM_006518471.2XP_006518534.1  BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like isoform X1

      Conserved Domains (1) summary
      pfam06553
      Location:17178
      BNIP3; BNIP3
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