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    Bcl7c B cell CLL/lymphoma 7C [ Mus musculus (house mouse) ]

    Gene ID: 12055, updated on 26-Sep-2022

    Summary

    Official Symbol
    Bcl7cprovided by MGI
    Official Full Name
    B cell CLL/lymphoma 7Cprovided by MGI
    Primary source
    MGI:MGI:1332237
    See related
    Ensembl:ENSMUSG00000030814 AllianceGenome:MGI:1332237
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C230096E12Rik
    Summary
    Predicted to act upstream of or within apoptotic process. Is expressed in embryo. Orthologous to human BCL7C (BAF chromatin remodeling complex subunit BCL7C). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in whole brain E14.5 (RPKM 8.6), CNS E18 (RPKM 7.8) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Bcl7c in Genome Data Viewer
    Location:
    7; 7 F3
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (127260626..127307938, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (127661454..127708766, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 51458 Neighboring gene predicted gene, 53373 Neighboring gene predicted gene, 39090 Neighboring gene microRNA 762 Neighboring gene cardiotrophin 1 Neighboring gene cardiotrophin 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    part_of GBAF complex IC
    Inferred by Curator
    more info
    PubMed 
    part_of SWI/SNF complex IC
    Inferred by Curator
    more info
    PubMed 
    part_of SWI/SNF complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of SWI/SNF complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in chromatin IC
    Inferred by Curator
    more info
    PubMed 

    General protein information

    Preferred Names
    B-cell CLL/lymphoma 7 protein family member C
    Names
    B-cell chronic lymphocytic leukemia/lymphoma 7C protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001347652.1NP_001334581.1  B-cell CLL/lymphoma 7 protein family member C isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AC124507
      Consensus CDS
      CCDS85422.1
      UniProtKB/TrEMBL
      A0A0U1RNX8
      Related
      ENSMUSP00000145743.2, ENSMUST00000205977.2
    2. NM_009746.2NP_033876.1  B-cell CLL/lymphoma 7 protein family member C isoform 2

      See identical proteins and their annotated locations for NP_033876.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus compared to isoform 1.
      Source sequence(s)
      BC005673
      Consensus CDS
      CCDS21874.1
      UniProtKB/Swiss-Prot
      O08664, Q99LS2
      UniProtKB/TrEMBL
      A0A8C6I0N8
      Related
      ENSMUSP00000057937.9, ENSMUST00000061468.9
      Conserved Domains (2) summary
      PHA03249
      Location:93177
      PHA03249; DNA packaging tegument protein UL25; Provisional
      pfam04714
      Location:450
      BCL_N; BCL7, N-terminal conserver region

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      127260626..127307938 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)