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    Bax BCL2-associated X protein [ Mus musculus (house mouse) ]

    Gene ID: 12028, updated on 12-Sep-2021

    Summary

    Official Symbol
    Baxprovided by MGI
    Official Full Name
    BCL2-associated X proteinprovided by MGI
    Primary source
    MGI:MGI:99702
    See related
    Ensembl:ENSMUSG00000003873
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Expression
    Ubiquitous expression in ovary adult (RPKM 20.8), placenta adult (RPKM 19.6) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Bax in Genome Data Viewer
    Location:
    7 B3; 7 29.32 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (45111119..45116344, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (45461695..45466903, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (52717065..52722268, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene RuvB-like protein 2 Neighboring gene glycogen synthase 1, muscle Neighboring gene ferritin light polypeptide 1 Neighboring gene dihydrodiol dehydrogenase (dimeric) Neighboring gene tubby-like protein 2 Neighboring gene nucleobindin 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables BH domain binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables BH3 domain binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables Hsp70 protein binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables channel activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables chaperone binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables chaperone binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables heat shock protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables lipid binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein heterodimerization activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables protein heterodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein homodimerization activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein-containing complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within B cell apoptotic process IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in B cell apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within B cell homeostasis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within B cell homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within B cell homeostatic proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within B cell negative selection IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in B cell receptor apoptotic signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within Sertoli cell proliferation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within T cell homeostatic proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in activation of cysteine-type endopeptidase activity involved in apoptotic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within activation of cysteine-type endopeptidase activity involved in apoptotic process IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within activation of cysteine-type endopeptidase activity involved in apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in activation of cysteine-type endopeptidase activity involved in apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within apoptotic mitochondrial changes IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in apoptotic mitochondrial changes ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within apoptotic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within apoptotic process involved in blood vessel morphogenesis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within apoptotic process involved in embryonic digit morphogenesis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within apoptotic signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in apoptotic signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within blood vessel remodeling IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within cell population proliferation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within cell population proliferation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in cellular respiration ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within cellular response to DNA damage stimulus IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within cellular response to UV IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within cellular response to organic substance IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in cellular response to virus ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within cerebral cortex development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within development of secondary sexual characteristics IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within ectopic germ cell programmed cell death IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within ectopic germ cell programmed cell death IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in establishment or maintenance of transmembrane electrochemical gradient ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in extrinsic apoptotic signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in extrinsic apoptotic signaling pathway in absence of ligand IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within extrinsic apoptotic signaling pathway in absence of ligand IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within extrinsic apoptotic signaling pathway via death domain receptors IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within fertilization IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within germ cell development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within glycosphingolipid metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within homeostasis of number of cells IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within homeostasis of number of cells IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within homeostasis of number of cells within a tissue IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within hypothalamus development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in inner mitochondrial membrane organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in intrinsic apoptotic signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within intrinsic apoptotic signaling pathway by p53 class mediator IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in intrinsic apoptotic signaling pathway in response to DNA damage IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within intrinsic apoptotic signaling pathway in response to DNA damage IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within intrinsic apoptotic signaling pathway in response to DNA damage IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within kidney development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within leukocyte homeostasis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within limb morphogenesis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within male gonad development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within male gonad development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in mitochondrial fragmentation involved in apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mitochondrial fusion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within mitochondrial fusion IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in mitochondrial fusion ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within mitochondrion morphogenesis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within myeloid cell homeostasis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within negative regulation of apoptotic signaling pathway IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within negative regulation of cell population proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within negative regulation of endoplasmic reticulum calcium ion concentration IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within negative regulation of fibroblast proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of mitochondrial membrane potential ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within negative regulation of neuron apoptotic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within negative regulation of peptidyl-serine phosphorylation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in negative regulation of protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within nervous system development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within neuron apoptotic process IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within neuron apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within neuron migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within odontogenesis of dentin-containing tooth IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in outer mitochondrial membrane organization ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within ovarian follicle development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within ovarian follicle development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within positive regulation of B cell apoptotic process IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in positive regulation of apoptotic DNA fragmentation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of apoptotic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within positive regulation of apoptotic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within positive regulation of apoptotic process IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within positive regulation of apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within positive regulation of apoptotic process involved in mammary gland involution IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within positive regulation of calcium ion transport into cytosol IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within positive regulation of developmental pigmentation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in positive regulation of endoplasmic reticulum unfolded protein response ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within positive regulation of extrinsic apoptotic signaling pathway in absence of ligand IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within positive regulation of intrinsic apoptotic signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of intrinsic apoptotic signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within positive regulation of mitochondrial membrane permeability involved in apoptotic process IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within positive regulation of neuron apoptotic process IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within positive regulation of neuron apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of neuron apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of neuron apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of protein-containing complex assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of release of cytochrome c from mitochondria ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within positive regulation of release of sequestered calcium ion into cytosol IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within post-embryonic camera-type eye morphogenesis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within post-embryonic development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within protein insertion into mitochondrial membrane involved in apoptotic signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within regulation of cell cycle IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within regulation of cysteine-type endopeptidase activity involved in apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within regulation of mammary gland epithelial cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within regulation of mitochondrial membrane permeability involved in apoptotic process IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within regulation of mitochondrial membrane permeability involved in programmed necrotic cell death IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    NOT acts_upstream_of_or_within regulation of mitochondrial membrane potential IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within regulation of neuron apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within regulation of nitrogen utilization IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in release of cytochrome c from mitochondria IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within release of cytochrome c from mitochondria IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within release of cytochrome c from mitochondria IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in release of cytochrome c from mitochondria ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in release of matrix enzymes from mitochondria ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within response to axon injury IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within response to gamma radiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within response to ionizing radiation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within response to ionizing radiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within response to salt stress IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within response to toxic substance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in response to toxic substance ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within response to wounding IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within retina development in camera-type eye IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within retinal cell programmed cell death IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within sex differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within spermatid differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within spermatogenesis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within spermatogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in supramolecular fiber organization ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within thymocyte apoptotic process IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within vagina development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within viral process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of BAK complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of BAX complex IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    part_of BAX complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of Bcl-2 family protein complex ISO
    Inferred from Sequence Orthology
    more info
     
    colocalizes_with cell periphery ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in integral component of membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    located_in intracellular anatomical structure IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrial membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in mitochondrial membrane ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in mitochondrial outer membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in mitochondrial outer membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in mitochondrial outer membrane ISO
    Inferred from Sequence Orthology
    more info
     
    part_of mitochondrial permeability transition pore complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear envelope ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in perinuclear region of cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    part_of pore complex ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_007527.3NP_031553.1  apoptosis regulator BAX

      See identical proteins and their annotated locations for NP_031553.1

      Status: VALIDATED

      Source sequence(s)
      AK013298, AV355155, CJ078904
      Consensus CDS
      CCDS21246.1
      UniProtKB/Swiss-Prot
      Q07813
      UniProtKB/TrEMBL
      Q544Z6
      Related
      ENSMUSP00000033093.9, ENSMUST00000033093.10
      Conserved Domains (1) summary
      TIGR00865
      Location:5192
      bcl-2; apoptosis regulator

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      45111119..45116344 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006540584.5XP_006540647.1  apoptosis regulator BAX isoform X1

      UniProtKB/TrEMBL
      A0A1B0GT81
      Related
      ENSMUSP00000148240.2, ENSMUST00000211365.2
      Conserved Domains (1) summary
      TIGR00865
      Location:5158
      bcl-2; apoptosis regulator
    2. XM_011250780.4XP_011249082.1  apoptosis regulator BAX isoform X2

      Conserved Domains (1) summary
      TIGR00865
      Location:5158
      bcl-2; apoptosis regulator
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