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    Atp6v0d1 ATPase, H+ transporting, lysosomal V0 subunit D1 [ Mus musculus (house mouse) ]

    Gene ID: 11972, updated on 31-Jan-2019

    Summary

    Official Symbol
    Atp6v0d1provided by MGI
    Official Full Name
    ATPase, H+ transporting, lysosomal V0 subunit D1provided by MGI
    Primary source
    MGI:MGI:1201778
    See related
    Ensembl:ENSMUSG00000013160
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    P39; Ac39; VATX; Vma6; Atp6d; AI267038
    Expression
    Ubiquitous expression in cortex adult (RPKM 82.2), cerebellum adult (RPKM 80.8) and 28 other tissues See more
    Orthologs

    Genomic context

    See Atp6v0d1 in Genome Data Viewer
    Location:
    8; 8 D3
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 8 NC_000074.6 (105524470..105566040, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (108048370..108089940, complement)

    Chromosome 8 - NC_000074.6Genomic Context describing neighboring genes Neighboring gene ferritin light chain 1 pseudogene Neighboring gene hydroxysteroid 11-beta dehydrogenase 2 Neighboring gene predicted gene, 38250 Neighboring gene agouti related neuropeptide Neighboring gene 40S ribosomal protein S2 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (1) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    protein-containing complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    proton transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    proton-exporting ATPase activity, phosphorylative mechanism IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    proton-exporting ATPase activity, phosphorylative mechanism IDA
    Inferred from Direct Assay
    more info
    PubMed 
    proton-transporting ATPase activity, rotational mechanism IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    ATP hydrolysis coupled proton transport IEA
    Inferred from Electronic Annotation
    more info
     
    cell projection organization IEA
    Inferred from Electronic Annotation
    more info
     
    cellular iron ion homeostasis ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to increased oxygen levels ISO
    Inferred from Sequence Orthology
    more info
     
    ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    vacuolar acidification IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    vacuolar transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    apical plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    axon terminus ISO
    Inferred from Sequence Orthology
    more info
     
    colocalizes_with centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    early endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    early endosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    lysosomal membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    membrane ISO
    Inferred from Sequence Orthology
    more info
     
    neuron projection ISO
    Inferred from Sequence Orthology
    more info
     
    plasma membrane proton-transporting V-type ATPase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     
    proton-transporting V-type ATPase, V0 domain IEA
    Inferred from Electronic Annotation
    more info
     
    synaptic vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    vacuolar proton-transporting V-type ATPase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    vacuolar proton-transporting V-type ATPase complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    V-type proton ATPase subunit d 1
    Names
    ATPase, H+ transporting, V0 subunit D
    ATPase, H+ transporting, lysosomal (vacuolar proton pump), 42 kDa
    ATPase, H+ transporting, lysosomal 38kDa, V0 subunit D
    V-ATPase 40 kDa accessory protein
    V-ATPase AC39 subunit
    V-ATPase subunit d 1
    lysosomal 38kDa
    physophilin
    vacuolar proton pump subunit d 1
    NP_038505.2

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_013477.4NP_038505.2  V-type proton ATPase subunit d 1

      See identical proteins and their annotated locations for NP_038505.2

      Status: VALIDATED

      Source sequence(s)
      AC151573, AK083372, CD776853
      Consensus CDS
      CCDS22604.1
      UniProtKB/Swiss-Prot
      P51863
      Related
      ENSMUSP00000013304.6, ENSMUST00000013304.7
      Conserved Domains (1) summary
      pfam01992
      Location:16344
      vATP-synt_AC39; ATP synthase (C/AC39) subunit

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000074.6 Reference GRCm38.p4 C57BL/6J

      Range
      105524470..105566040 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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