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    Atp5b ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit [ Mus musculus (house mouse) ]

    Gene ID: 11947, updated on 31-Jan-2019

    Summary

    Official Symbol
    Atp5bprovided by MGI
    Official Full Name
    ATP synthase, H+ transporting mitochondrial F1 complex, beta subunitprovided by MGI
    Primary source
    MGI:MGI:107801
    See related
    Ensembl:ENSMUSG00000025393
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Atp5f1b
    Expression
    Ubiquitous expression in heart adult (RPKM 1957.4), kidney adult (RPKM 1315.7) and 28 other tissues See more
    Orthologs

    Genomic context

    See Atp5b in Genome Data Viewer
    Location:
    10; 10 D3
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 10 NC_000076.6 (128083307..128090388)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (127520363..127527444)

    Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene nascent polypeptide-associated complex alpha polypeptide Neighboring gene prostaglandin E synthase 3 Neighboring gene microRNA 677 Neighboring gene bromodomain adjacent to zinc finger domain, 2A Neighboring gene RNA binding motif, single stranded interacting protein 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ADP binding ISO
    Inferred from Sequence Orthology
    more info
     
    ATP binding ISO
    Inferred from Sequence Orthology
    more info
     
    ATPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    contributes_to ATPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    MHC class I protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    angiostatin binding ISO
    Inferred from Sequence Orthology
    more info
     
    calcium ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    lipoprotein particle receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    proton-transporting ATP synthase activity, rotational mechanism ISO
    Inferred from Sequence Orthology
    more info
     
    proton-transporting ATPase activity, rotational mechanism ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    ATP biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    ATP metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    ATP synthesis coupled proton transport IEA
    Inferred from Electronic Annotation
    more info
     
    angiogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to interleukin-7 IDA
    Inferred from Direct Assay
    more info
    PubMed 
    ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    lipid metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of cell adhesion involved in substrate-bound cell migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of blood vessel endothelial cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    proton transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    receptor-mediated endocytosis ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of intracellular pH ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cell surface ISO
    Inferred from Sequence Orthology
    more info
     
    membrane ISO
    Inferred from Sequence Orthology
    more info
     
    membrane raft ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrial inner membrane HDA PubMed 
    mitochondrial inner membrane ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrial membrane ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrial nucleoid ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrial proton-transporting ATP synthase complex ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrion HDA PubMed 
    mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    myelin sheath HDA PubMed 
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    proton-transporting ATP synthase complex ISO
    Inferred from Sequence Orthology
    more info
     
    proton-transporting ATP synthase complex, catalytic core F(1) ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    ATP synthase subunit beta, mitochondrial
    Names
    ATP synthase F1 subunit beta
    ATP synthase, H+ transporting mitochondrial F1 complex, alpha subunit
    mitochondrial ATP synthase, H+ transporting F1 complex beta subunit
    NP_058054.2

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_016774.3NP_058054.2  ATP synthase subunit beta, mitochondrial precursor

      See identical proteins and their annotated locations for NP_058054.2

      Status: VALIDATED

      Source sequence(s)
      AC131120
      Consensus CDS
      CCDS24259.1
      UniProtKB/Swiss-Prot
      P56480
      Related
      ENSMUSP00000026459.5, ENSMUST00000026459.5
      Conserved Domains (1) summary
      PRK09280
      Location:58524
      PRK09280; F0F1 ATP synthase subunit beta; Validated

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000076.6 Reference GRCm38.p4 C57BL/6J

      Range
      128083307..128090388
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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