Format

Send to:

Choose Destination
    • Showing Current items.

    Atf1 activating transcription factor 1 [ Mus musculus (house mouse) ]

    Gene ID: 11908, updated on 31-Jan-2019

    Summary

    Official Symbol
    Atf1provided by MGI
    Official Full Name
    activating transcription factor 1provided by MGI
    Primary source
    MGI:MGI:1298366
    See related
    Ensembl:ENSMUSG00000023027
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Expression
    Ubiquitous expression in testis adult (RPKM 24.0), liver E14 (RPKM 14.5) and 28 other tissues See more
    Orthologs

    Genomic context

    See Atf1 in Genome Data Viewer
    Location:
    15; 15 F1
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 15 NC_000081.6 (100227859..100261248)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (100058290..100091679)

    Chromosome 15 - NC_000081.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 2310068J16 gene Neighboring gene La ribonucleoprotein domain family, member 4 Neighboring gene disco interacting protein 2 homolog B Neighboring gene transmembrane (C-terminal) protease, serine 12 Neighboring gene predicted gene, 33666

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    DNA-binding transcription activator activity, RNA polymerase II-specific ISO
    Inferred from Sequence Orthology
    more info
     
    DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    DNA-binding transcription factor activity, RNA polymerase II-specific ISO
    Inferred from Sequence Orthology
    more info
     
    RNA polymerase II regulatory region sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein heterodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    protein-containing complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    cellular protein-containing complex assembly ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of DNA replication ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of neuron projection development ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    ATF1-ATF4 transcription factor complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    ATF1-ATF4 transcription factor complex ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    transcription factor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    transcription factor complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    transcription factor complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    cyclic AMP-dependent transcription factor ATF-1
    Names
    TCR-ATF1
    cAMP-dependent transcription factor ATF-1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_007497.3NP_031523.3  cyclic AMP-dependent transcription factor ATF-1

      See identical proteins and their annotated locations for NP_031523.3

      Status: VALIDATED

      Source sequence(s)
      AC124479, AK010428, BY733806
      Consensus CDS
      CCDS27832.1
      UniProtKB/Swiss-Prot
      P81269
      UniProtKB/TrEMBL
      Q9CWS2
      Related
      ENSMUSP00000023769.4, ENSMUST00000023769.10
      Conserved Domains (2) summary
      cd14690
      Location:213267
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:4882
      pKID; pKID domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000081.6 Reference GRCm38.p4 C57BL/6J

      Range
      100227859..100261248
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006520351.3XP_006520414.1  cyclic AMP-dependent transcription factor ATF-1 isoform X1

      See identical proteins and their annotated locations for XP_006520414.1

      UniProtKB/Swiss-Prot
      P81269
      Conserved Domains (2) summary
      cd14690
      Location:213267
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:4882
      pKID; pKID domain
    2. XM_006520352.3XP_006520415.1  cyclic AMP-dependent transcription factor ATF-1 isoform X1

      See identical proteins and their annotated locations for XP_006520415.1

      UniProtKB/Swiss-Prot
      P81269
      Conserved Domains (2) summary
      cd14690
      Location:213267
      bZIP_CREB1; Basic leucine zipper (bZIP) domain of Cyclic AMP-responsive element-binding protein 1 (CREB1) and similar proteins: a DNA-binding and dimerization domain
      pfam02173
      Location:4882
      pKID; pKID domain
    Support Center