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    Ate1 arginyltransferase 1 [ Mus musculus (house mouse) ]

    Gene ID: 11907, updated on 19-Mar-2019

    Summary

    Official Symbol
    Ate1provided by MGI
    Official Full Name
    arginyltransferase 1provided by MGI
    Primary source
    MGI:MGI:1333870
    See related
    Ensembl:ENSMUSG00000030850
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AI225793; AW547406
    Expression
    Ubiquitous expression in placenta adult (RPKM 5.0), CNS E18 (RPKM 4.1) and 28 other tissues See more
    Orthologs

    Genomic context

    See Ate1 in Genome Data Viewer
    Location:
    7; 7 F3
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 7 NC_000073.6 (130391493..130521274, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (137535007..137663475, complement)

    Chromosome 7 - NC_000073.6Genomic Context describing neighboring genes Neighboring gene ring finger and WD repeat domain 3 pseudogene Neighboring gene predicted gene, 33771 Neighboring gene predicted gene 4275 Neighboring gene NSE4 homolog A, SMC5-SMC6 complex component Neighboring gene transforming, acidic coiled-coil containing protein 2 Neighboring gene predicted gene, 34365

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    arginyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    arginyltransferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    transferase activity, transferring acyl groups IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    proteasomal protein catabolic process ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    protein arginylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein arginylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    arginyl-tRNA--protein transferase 1
    Names
    R-transferase 1
    arginine-tRNA--protein transferase 1
    NP_001025066.1
    NP_001129526.1
    NP_001258272.1
    NP_038827.2
    XP_006507327.1
    XP_006507328.1
    XP_006507330.1
    XP_011239961.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001029895.3NP_001025066.1  arginyl-tRNA--protein transferase 1 isoform 3

      See identical proteins and their annotated locations for NP_001025066.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) uses an alternate 5' structure, compared to variant 1. This difference causes translation initiation at an upstream AUG and results in an isoform (3) that has a distinct N-terminus and is shorter, compared to isoform 1.
      Source sequence(s)
      AK077471, AK158613, BC050948
      Consensus CDS
      CCDS21901.1
      UniProtKB/TrEMBL
      Q4FCQ7, Q80YP1, Q8BP95
      Related
      ENSMUSP00000091556.3, ENSMUST00000094017.4
      Conserved Domains (2) summary
      pfam04376
      Location:1685
      ATE_N; Arginine-tRNA-protein transferase, N terminus
      pfam04377
      Location:281422
      ATE_C; Arginine-tRNA-protein transferase, C terminus
    2. NM_001136054.2NP_001129526.1  arginyl-tRNA--protein transferase 1 isoform 4

      See identical proteins and their annotated locations for NP_001129526.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) uses an alternate in-frame exon in the coding region, compared to variant 1. It encodes isoform 4.
      Source sequence(s)
      BC050948, BY123375
      Consensus CDS
      CCDS52414.1
      UniProtKB/TrEMBL
      Q80YP1
      Related
      ENSMUSP00000043365.7, ENSMUST00000035458.14
      Conserved Domains (2) summary
      pfam04376
      Location:2092
      ATE_N; Arginine-tRNA-protein transferase, N terminus
      pfam04377
      Location:288429
      ATE_C; Arginine-tRNA-protein transferase, C terminus
    3. NM_001271343.1NP_001258272.1  arginyl-tRNA--protein transferase 1 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate 5' structure and an alternate in-frame exon in the coding region, compared to variant 1. These differences cause translation initiation at an upstream AUG and result in an isoform (2) that has a distinct N-terminus and is shorter, compared to isoform 1.
      Source sequence(s)
      AK158613, BC050948, DQ093640
      Consensus CDS
      CCDS72051.1
      UniProtKB/TrEMBL
      J3QNU1, Q4FCQ6, Q80YP1
      Related
      ENSMUSP00000136956.1, ENSMUST00000178534.7
      Conserved Domains (2) summary
      pfam04376
      Location:1685
      ATE_N; Arginine-tRNA-protein transferase, N terminus
      pfam04377
      Location:281422
      ATE_C; Arginine-tRNA-protein transferase, C terminus
    4. NM_013799.3NP_038827.2  arginyl-tRNA--protein transferase 1 isoform 1

      See identical proteins and their annotated locations for NP_038827.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes isoform 1.
      Source sequence(s)
      BC042601, BY123375
      Consensus CDS
      CCDS21902.1
      UniProtKB/Swiss-Prot
      Q9Z2A5
      Related
      ENSMUSP00000033139.7, ENSMUST00000033139.14
      Conserved Domains (2) summary
      pfam04376
      Location:2092
      ATE_N; Arginine-tRNA-protein transferase, N terminus
      pfam04377
      Location:288429
      ATE_C; Arginine-tRNA-protein transferase, C terminus

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000073.6 Reference GRCm38.p4 C57BL/6J

      Range
      130391493..130521274 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006507264.2XP_006507327.1  arginyl-tRNA--protein transferase 1 isoform X1

      UniProtKB/TrEMBL
      A0A1L1SQ41
      Related
      ENSMUSP00000148888.1, ENSMUST00000216011.1
      Conserved Domains (2) summary
      pfam04376
      Location:2092
      ATE_N; Arginine-tRNA-protein transferase, N terminus
      pfam04377
      Location:331472
      ATE_C; Arginine-tRNA-protein transferase, C terminus
    2. XM_006507265.3XP_006507328.1  arginyl-tRNA--protein transferase 1 isoform X2

      Conserved Domains (2) summary
      pfam04376
      Location:1685
      ATE_N; Arginine-tRNA-protein transferase, N terminus
      pfam04377
      Location:324465
      ATE_C; Arginine-tRNA-protein transferase, C terminus
    3. XM_011241659.1XP_011239961.1  arginyl-tRNA--protein transferase 1 isoform X3

      Conserved Domains (2) summary
      pfam04376
      Location:2092
      ATE_N; Arginine-tRNA-protein transferase, N terminus
      pfam04377
      Location:331460
      ATE_C; Arginine-tRNA-protein transferase, C terminus
    4. XM_006507267.3XP_006507330.1  arginyl-tRNA--protein transferase 1 isoform X4

      Conserved Domains (1) summary
      pfam04376
      Location:2092
      ATE_N; Arginine-tRNA-protein transferase, N terminus
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