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    Arpc1b actin related protein 2/3 complex, subunit 1B [ Mus musculus (house mouse) ]

    Gene ID: 11867, updated on 31-Jan-2019

    Summary

    Official Symbol
    Arpc1bprovided by MGI
    Official Full Name
    actin related protein 2/3 complex, subunit 1Bprovided by MGI
    Primary source
    MGI:MGI:1343142
    See related
    Ensembl:ENSMUSG00000029622
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    L72; 41kDa; SOP2Hs; p41-ARC; AA408064; AA408534; AA571392; AF007010; AW208418
    Expression
    Broad expression in colon adult (RPKM 219.0), ovary adult (RPKM 201.5) and 23 other tissues See more
    Orthologs

    Genomic context

    See Arpc1b in Genome Data Viewer
    Location:
    5; 5 G2
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 5 NC_000071.6 (145114256..145128186)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (145875125..145889055)

    Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1700018F24 gene Neighboring gene actin related protein 2/3 complex, subunit 1A Neighboring gene PDGFA associated protein 1 Neighboring gene BUD31 homolog Neighboring gene pentatricopeptide repeat domain 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC102425

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    actin binding IEA
    Inferred from Electronic Annotation
    more info
     
    actin filament binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    contributes_to actin filament binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein-containing complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    structural constituent of cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    Arp2/3 complex-mediated actin nucleation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Arp2/3 complex-mediated actin nucleation ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of actin filament polymerization IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    Arp2/3 protein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Arp2/3 protein complex ISO
    Inferred from Sequence Orthology
    more info
     
    Arp2/3 protein complex TAS
    Traceable Author Statement
    more info
    PubMed 
    actin cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    tubulobulbar complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    actin-related protein 2/3 complex subunit 1B
    Names
    arp2/3 complex 41 kDa subunit

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_023142.2NP_075631.2  actin-related protein 2/3 complex subunit 1B

      See identical proteins and their annotated locations for NP_075631.2

      Status: VALIDATED

      Source sequence(s)
      AK153510, AK159371, BF660612
      Consensus CDS
      CCDS19856.1
      UniProtKB/Swiss-Prot
      Q9WV32
      Related
      ENSMUSP00000082822.6, ENSMUST00000085679.12
      Conserved Domains (2) summary
      sd00039
      Location:1150
      7WD40; WD40 repeat [structural motif]
      cl25539
      Location:45264
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000071.6 Reference GRCm38.p4 C57BL/6J

      Range
      145114256..145128186
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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